Pulmonary infections Flashcards
common cold bugs
***rhino virus
corona, adeno, echo, coxa/b, flu, paraflu, rsv, mycoplas pneu, human metapneu
common cold keys
usually no fever, present in winter months
summer gripe bugs
coxA/B, echo, enteroviruses
summer gripe keys
cold-like febrile illness in summer
summer gripe presentation
non-specific febrile illness w malaise and headache. Sx 3-4 days
viral acute rhinosinu bugs
rhino, parainflu, RSV adeno
viral acute rhinosinu keys
Sx resolve in 5-7 days
viral acute rhinosinu presentation
do i really need to describe this??
bacterial acute rhinosinu bugs
**S pneumoniae, non typable H flu
also
anaerobes
g-
s aureus, moraxella, pyogenes
bacterial acute rhinosinu keys
adult w mod symptoms >7d, or severe sx develop (facial swelling/tooth pain)
child w mod sx >10-14d or severe (>102, facial swelling, AMS)
bacterial acute rhinosinu presentation
mucosal inflammation
sneezing, rhinorrhea, pressue and headache etc
usually follows viral
rhinocerebral mucormycosis bugs
***rhizopus, rhizomucor
also mucor, mycocladus, cunninghamella
rhinocerebral mucormycosis keys
black eschar of palate
very rare
rhinocerebral mucormycosis presentation
rhinosinusitis w bloody nasal discharge, dusky turbinates, AMS
black eschar, abscesses, decreased ocular motion
viral pharyngitis bugs
adeno, HSV, EBV, CoxAB
viral pharyngitis keys
conjunctivitis, cough, coryza, discrete ulcerative lesions, anterior stomatitis
viral pharyngitis presentation
fever, sore throat, edema, hyperemia of the tonsils
bacterial pharyngitis bugs
strep pyogenes
bacterial pharyngitis keys
complications if untreated– abscess, mastoiditis, cervical lympadenitis
acute glomerulonephritis, rheumatic fever
bacterial pharyngitis presentation
fever, sore throat, hyperemia of the tonsils
pyogenes: fever and severe pain, tonsilopharyngeal erthema w or w/o exudate, lymphadenitis. petechiae, scarlet rash, swollen uvula
kids- N/V, abd pain
lemierre’s (post-anginal septicemia) bugs
fusobacterium nerophorum
lemierre’s (post-anginal septicemia) presentation
sore throat progressing to thrombophlebitis of IJV w pain, dysphagia, neck swelling, stiffness. sepsis in 3-10d after sore throat. can spread to lungs
diphtheria bugs
corynebacterium diphtheriae
diphtheria keys
pseudomembrane, bleeding upon removal, cervical lymphadenopathy, difficulty swallowing
diphtheria presentation
pharyngeal pain, pseudomembrane, bull neck, fetid breath.
airway obstruction and toxemia can occur
viral acute pharyngitis bugs
so many bugs: parainflu, flu AB, adeno, RSV, HSV, rhino, coxAB, echo
viral acute pharyngitis keys
clinical s/s
viral acute pharyngitis presentation
begins as URTI, followed by hoarseness and reduced vocal pitch
odynophagia, odynophonia, congestion, fatigue, malaise,
laryngeal edema and vascular engorgement of vocal folds
bacterial acute pharyngitis bugs
pyogenes
bacterial acute pharyngitis keys
+ bacterial culture
bacterial acute pharyngitis
same as viral, less common
begins as URTI, followed by hoarseness and reduced vocal pitch
odynophagia, odynophonia, congestion, fatigue, malaise,
laryngeal edema and vascular engorgement of vocal folds
viral croup/ laryngotracheobonchitis bugs
parainfluenza type 1
also parainflu2, fluAB, adeno, RSV, HSV, rhino, CoxAB, echo
viral croup/ laryngotracheobonchitis key
barking cough, inspiratory stridor and retractions
less air hunger after racemic epi or humid air (no effect on bact epiglotitis)
steeple sign
normal swallow
viral croup/ laryngotracheobonchitis presentation
higher fever than laryngitis, restlessness, air hunger
starts with mild URTI 2-3 d
followed by barking cough, stridor at night
normal lungs, maybe mild expiratory wheeze
nasal flaring, lethargy,
if severe, tachypnea, tachycardia, hypoxemia, hypotonia, cyanosis
s/s peak 3-5d, resolve 4-7d
bacterial epiglottitis and supraglottitis bugs
H flu B
bacterial epiglottitis and supraglottitis keys
difficult swallow
distressed, toxic looking
thumb sign
no response to racemic epi or humid air
epiglottitis triad= sore throat with dysphagia, hoarse voice, generally unwell/dehydrated
bacterial epiglottitis and supraglottitis presentation
acute onset fever, sore throat, cough suprasternal notch retraction and stridor inflamed throat beefy red epiglottis
progresses rapidly= severe dyspnea, cyanosis, toxicity
four Ds= dysphagia, dysphonia, drooling, distress
acute bronchitis bugs
flu AB, paraflu, adeno, RSV, HSV, rhino, CoxAB, echo
mycoplas pneumoniae
chlamydophilia pneumoniae
acute bronchitis keys
clinical s/s
CXR
acute bronchitis presentation
non productive cough, substernal pain, fever. rhonchi, moist crackles
several hours bf cough= malaise, headache, coryza, sore throat
bronchiolitis bugs
RSV
bronchiolitis keys
observe s/s, Ag testing in nasal washings
CXR= hyperinflation, patchy infiltrate, air trapping, flat diaphragm, peribronchial cuffing
bronchiolitis presentation
rhinorrhea, cough, low fever
can lead to paroxysmal cough and dyspnea
tachypnea, tachycardia, fever, wheezing, grunting, vomiting, cyanosis
influenza bugs
flu AB
influenza keys
high fever, acute onset, lab confirmation
influenza presentation
abrupt onset of fever, chills, rigor, headache, prostration, nonproductive cough, V/D in kids
fever abates in 3-4d, cough and malaise persist for 2w
can lead to pneumonia w secondary bacteria ie aureus, hflu, strep pneumo, pyogenes
pertussis bugs
bordetella pertussis
pertussis key
whoop is pathognomonic
NP aspirates on bordet gengou medium
ELISA, IFS
Elevate WBC, lymphocytosis in kids
pertussis presentation
catarrhal phase 1-2w: coryza, sneezing, low fever, mild cough
paroxysmal phase 2-4 weeks: inspiratory whoop with posttussis vom
typical pneumonia bugs
***strep pneumoniae
klebsiella, pseudomonas, g-rods
typical pneumonia keys
sudden, rigors, toxic looking, productive cough, bloody/purulent sputum, high fever,
neutrophils, WBC>15K w L shift
purulent vs mucoid sputum
purulent=typical, mucoid=atypical
rust vs green sputum
rust = strep pneumo
green =pseudomonas or H flu
klebsiella pneumonia
currant jelly
bowing fissure w UL consolidation
can cause necrosis
pseudomonas pneumonia
microabscesses which can coalesce
staph aureus pneumonia
bilateral nodular infiltrates w cavitation
in kids = pneumatoceles, bronchopleural fistulas, empyema
typical pneumonia presentation
develop within 24-48 hours high fever shaking chills dyspnea tachycardia flu like symptoms
EXCEPTION: neonate afebrile chlamydia trachomatis pneumonia
typical pneumonia in CF
pseudomonas or s aureus
typical pneumonia in alcohol
klebsiella or oral anaerobe from aspiration
typical pneumonia in nursing home
enteric gram neg (enterobacter, klebsiella, e coli)
typical pneumonia in copd
H flu, klebsiella
typical pneumonia in IV drug user
staph aureus
typical pneumonia in elderly or w recent flu
staph aureus
typical pneumonia in military, dorm, young people
neisseria meningitidis
atypical pneumonia bugs
mycoplasma pneumoniae
atypical pneumonia keys
gradual onset, well looking, nonproductive cough, mucoid sputum, low fever, rare pleurisy, rare consolidation
sputum: rare mononuclear cells, WBC>15K
interstitial infiltrate
atypical pneumonia presentation
subacute onset, 1 week to develop symptoms, paroxysmal cough w mucoid/no sputum
afebrile pneumonia
neonates, chlamydia trachomatis
atypical pneumonia IC
pneumocystis jiroveci
aspiration pneumonia presentation
like typical pneumonia, except with recurrent chills
consolidations in dependent lung segments
50% have foul sputum
increased minute ventilation
TB
mycobact tb
insidious onset, night sweats, low fever, wt loss, productive purulent cough, dyspnea, coin lesions
chronic pneumonia- histoplasmosis bugs
histoplasma capsulatum
chronic pneumonia- histoplasmosis presentation
erythema nodosum and hilar adenopathy, fungal pneumonia
chronic pneumonia- histoplasmosis keys
yeast cells in PMNs or monocytes
when grown in vitro at RT= hyphae and tuberculate macroconidia
captains wheel
chronic pneumonia coccidioidmycosis bugs
coccidiodes immitis
chronic pneumonia coccidioidmycosis presentation
erythema nodosum and hilar adenopathy, fungal pneumonia
chronic pneumonia coccidioidmycosis keys
spherule seen in lung material (round with many speckles inside)
chronic pneumonia blastomycosis bug
blastomyes dermatitidis
chronic pneumonia blastomycosis presentation
fungal pneumonia which may also show verrucous skin lesions
chronic pneumonia blastomycosis keys
broad based budding yeast
psittacosis bug
chlamydophilia psittaci
psittacosis presentation
pneumonia with bradycardia, epistaxis, horder spots (rose spots), low leukocyte count
caretakers of birds
Q fever bug
coxiella burnetii
q fever presentation
pneumonia w bradycardia, hepatomegaly, endocarditis, abnl LFT.
farmers with recently birthed livestock
legionnaire’s disease bug
legionella pneumophilia
legionnaire’s disease presentation
pneumonia with bradycardia, abd pain, V/D, hematuria, confusion, abl LFT/renal fxn tests, increase CPK