Pulmonary Hypertension Flashcards
1
Q
What is the definition of Pulmonary HTN?
How is this measured non-invasively?
What is the definition in this method?
A
Mean pulmonary aterirla pressure >25mmHg at rest, at sea level
Doppler - Bernoulli equation - HTN >40mmHg
2
Q
What is the most common genetic cause of primary pulmonary hypertension?
Name some common acquired causes…
A
BMPR-2 gene defect
Acquired causes: Congenital heart disease with large L>R shunt, BPD, ILD, OSA, CF, left sided cardiac obstruction eg AS/COA, TAPVD with obstruction, chronic left heart failure, SLE, portal hypertension
3
Q
What are the expected clinical findings in a patient with pulmonary HTN?
A
Cyanosis
RV heave
Narrowly split and loud second heart sound
Gallop rhythm
4
Q
What are some treatment options?
A
Nasal nitric oxide Prostacyclin infusion Sildenafil Calcium channel blockers Heart-lung transplant
