Pulmonary HTN Flashcards
1
Q
How do you define pHTN
A
mPAP > 20 mmHg in > 3 month old at sea level
2
Q
How do you define pre-capillary pHTN?
A
mPAP > 20 and PCWP < 15
3
Q
How do you define post-capillary pHTN
A
mPAP > 20 and PCWP > 15
4
Q
What two gene mutations are associated with heritable pHTN?
A
TBX4 and BMPR2
5
Q
What combination of physiologic states is associated with early and aggressive PVD?
A
High flow state and high pressure state leading to sheer stress and wall tension
6
Q
A
7
Q
Describe the diagnostic algorithm for pHTN per the AHA/ATS guidelines
A
Echo > PFTs and sleep study > V/Q scan > cath
8
Q
Describe the treatment algorithm for pHTN per the AHA/ATS guidelines
A
Needs cath prior:
If AVT + -> CCB
If AVT -
– Low risk : Endothelin receptor antagonist or PGE5i
– High risk: Triple therapy with prostacyclin analog
9
Q
A
