Pulmonary Function Testing Flashcards

1
Q

What are the effort dependent tests?

A

Forced expiratory volumes
Flow rates
Spirometry

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2
Q

What are the effort independent tests?

A
Relaxed vital capacity (spirometry)
Helium/ Nitrogen washout for static lung volumes 
Whole body plethysmography
Impulse oscillometry
Exhaled breath nitric oxide
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3
Q

What are the gas diffusion tests?

A

CO transfer factor (TLCO)
ABGs
SaO2 during exercise

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4
Q

What is a forced expiratory manovre?

A

From total lung capacity to residual volume

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5
Q

What can you get from a flow volume curve?

A

Peak expiratory flow rate

Forced expiratory flow rate at a percentage of FVC

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6
Q

On a flow volume curve, what disease will show volume dependent airway closure and why?

A

Asthma and chronic bronchitis

Due to mucosal oedema

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7
Q

On a flow volume curve, what disease will show pressure dependent airway closure and why?

A

Emphysema

Due to loss of alveolar support

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8
Q

What does bronchial challenge testing measure?

A

Airway hyper responsiveness

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9
Q

A decreases SaO2 during exercise suggests which disease?

A

DPLD

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10
Q

Decreased FEV1 or PEF post exercise suggests which disease?

A

Asthma

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11
Q

What is being measured in a TLCO test?

A

The CO diffusion across the alveolar/arteriolar barrier

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12
Q

When would you see a decreased TLCO?

A
Anaemia 
Emphysema 
DPLD
Pulmonary oedema 
Pulmonary emboli 
Bronchiectasis
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13
Q

What is TLCO used for in DPLD patients?

A

Monitoring response to treatment

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14
Q

How is airway resistance measured?

A

Whole body plethysmography or with impulse oscillometry. Can be used in children who struggle with forced expiratory manovres

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15
Q

What is the exhaled breath condensate?

A

Exhaled nitric oxide measured at a flow of 50ml/s

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16
Q

What is the exhaled breath condensate used for and why is it not useful in COPD?

A

Used as a marker of eosinophilic inflammation in asthma. High levels of NO- >35ppb show uncontrolled inflammation
Not useful in COPD as NO is suppressed by smoking