Pulmonary Embolism Flashcards

1
Q

When will you suspect PE?

A
  • sudden collapse 1-2 weeks after surgery
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2
Q

What is the Px of PE?

A
  1. DVT develops in veins
  2. Embolise through veneous system into the right side of heart
  3. Travel to pulmonary arteries
  4. Block blood flow to lung tissue
  5. Create strain on right heart
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3
Q

Which veins do DVT commonly occur?

A
  • External iliac
  • Femoral
  • Popliteal
  • Posterior tibial
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4
Q

What are the 5 fates of a thrombus?

A
  • resolution
  • propagation
  • embolisation
  • organisation
  • recanulisation
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5
Q

What are the RF for PE?

A
  • Immobility
  • Recent surgery
  • Long haul flights
  • Pregnancy
  • Hormone therapy with oestrogen
  • Malignancy
  • Polycythaemia
  • SLE
  • Thrombophilia
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6
Q

What are the sx of PE?

A
  • dyspnoea
  • pleuritic chest pain - worse on inspiration
  • haemoptysis
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7
Q

What are the clinical signs of PE?

A
  • Hypotension
  • Reduced air entry
  • tachycardic
  • Tachypnea
  • loud P2
  • cyanosis
  • pleural rub
  • DVT signs
    • leg swelling
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8
Q
A
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9
Q

What scoring system will you use for PE?

A
  • Well’s criteria
  • Likely > perform CTPA
  • Unlikely > perform d-dimers. If + then CTPA
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10
Q

What is the definitive Ix of PE?

A
  • CTPA
  • V/Q scan
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11
Q

What other Ix would you order for PE?

A
  • Bedside
    • ECG
  • Bloods
    • FBC, U&E, clotting test, d-dimers
    • ABG
  • Imaging
    • CXR
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12
Q

What ECG features would PE show?

A
  • Normal (majority of times)
  • Sinus tachycardic
  • R Ventricular strain
    • inverted T wave (v1-v4)
  • S1Q3T3
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13
Q

What are the CXR features of PE?

A
  • Normal (majority of times)
  • small pleura effusion
  • enlarged pulmonary artery
  • atelactasis
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14
Q

How would you initially mx PE?

A
  • Oxygen - 10-15L/min
  • Morphine 5-10mg + antiemetic
  • Bolus fluid
  • First line:
    • Apixaban or rivaroxaban
  • If not suitable
    • LMWH
  • If massive PE/hemodynamically unstable
    • Thrombolytics
      • streptokinase, alteplase
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15
Q

How would you mx PE long term?

A
  • Warfarin
  • DOAC
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16
Q

What is the target INR for warfarin?

A
  • 2-3
17
Q

What must the patient be on when switching to warfarin?

A
  • LMWH 5 days
18
Q

Which anticoag is used as first line treatment in pregnancy and cancer longterm thromboembolic prophylaxis?

A
  • LMWH