pulmonary dx Flashcards
COPD stages according to this class
- Bronchitis (Stage I COPD)
- Emphysema (Stage II COPD)
lung anatomy
#lobes?
3 in R, 2 in L
airway path
trachea>primary bronchus>secondary bronchus>tertiary bronchi> respiratory bronchioles> alveoli
asthma
Chronic inflammatory airway disorder
* Airway hyper-responsiveness to stimuli
* Bronchial edema
* Narrowing of the airways i.e., obstruction
asthma airway events
smooth mm contraction and increased mucus
normal vs asthmatic airway
asthma signs and symptoms
Recurrent, reversible episodes of:
*Dyspnea (shortness of breath)
*Wheezing
*Coughing
*Tightness of chest
Which of the following is a “true”
asthma symptom?
*Dyspnea (shortness of breath)
*Wheezing
*Coughing
*Tightness of chest
chest tightness
asthma aggrivating and complicating factors
● Smoking
● Air pollutants (quality)
- urban
- industrial
stages of asthma
- Controlled
- Partially Controlled
- Uncontrolled
controlled asthma
partially controlled asthma
uncontrolled asthma
types of asthma
- Extrinsic
- Exercise Induced
- Intrinsic
- Drug Induced
extrinsic asthma
* common?
* demo?
* family history?
* Triggered by?
* Exaggerated host response?
- Most common
- Children and young adults
- Typical positive family history
- Triggered by allergens (pollen, dust, house
mites, animal dander, mold etc.) - Exaggerated inflammatory response
extrinsic asthma pathway
Allergen→ T Helper Lymphocyte Type 2 (Th2)
→ antibody production of high levels of IgE → activation of mast cells, basophils and eosinophils → bradykinin, histamine, leukotrienes → bronchoconstriction
exercise induced asthma
* Unknown?
* demo?
* Triggered by?
* Cold air role?
- Unknown pathogenesis
- Children and young adults
- Triggered by exercise and thermal changes
- Cold air irritates mucosa resulting in airway
hyperactivity
exercise induced asthma pathway
Allergen→ T Helper Lymphocyte Type 2 (Th2)
→ antibody production of high levels of IgE
→ activation of mast cells, basophils and eosinophils
→ bradykinin, histamine, leukotrienes
→ bronchoconstriction
same as extrinsic
intrinsic asthma
* common?
* demo?
* Triggered by?
* Infrequently associated with?
- Second most common
- Middle-aged individuals
- Triggered by respiratory irritants (tobacco, air
pollution, emotional stress, gastroesophageal reflux
disease (GERD) - Infrequently associated with family history
how is intrinsic asthma pathway dif from the others?
normal IgE levels
drug indcued asthma
subset of?
demo?
- Subset of intrinsic
- Affects children, young adults & middle-aged adults
common drugs of drug induced asthma
➢NSAIDs, ASA
➢β-blockers
➢ACEi
➢Anticholinergic drugs (?)
➢Food dye
➢Metabisulfites in food and in local anesthetics with
epinephrine
asthma tx
inhaled B2 agonists
SABA
LABA
inhlaed b2 agonists
bind to ẞ2 receptors in lungs
smooth muscle relaxation
i.e., bronchodilation
SABA
are single use (rescue) medications used alone
LABA
used in combination with steroids on a scheduled protocol used alone leads to CVD complications ( arrythmias, etc)
side effects asthma tx
Tremors
tachycardia
Increases blood sugar
Cough
K decrease
common SABA
albuterol
LABA often used with what asthma stage
uncontrolled
anticholergenics used for asthma
atrovent and spiriva
methyxanthine used for asthma
theophylline
mast cell stabilizer for asthma
cromolyn
corticosteroids for asthma
used with LABA
demethasone, fludrocotisone, methylprednisolone, predinosone
LT receptor antag for asthma name
singulair
combo inhalers names
advair diskus and symbicort
asthma oral signs
- Mouth breather (high palatal vault, overjet, crossbite, greater facial height)
- Dry mouth
- Candida
- Enamel defects and caries
- Gingivitis/periodontitis
- Enamel erosion possible with GERD
uncontrolled Asthma
Dental Treatment Considerations
- Dental treatment should be limited to urgent care
only - Treatment of acute pain, bleeding, or infection