Pulmonary Anatomy and Physiology Flashcards
4 functions of respiratory system
- Ventilation and perfusion
- Respiration
- Transport of O2 and CO2
- Diffusion of O2 and CO2
It is the act of moving air in and out of lungs
Ventilation
Law of Physics for ventilation
Boyle’s Law
inhale = air goes in our lungs; exhale = air goes outside our lungs
It is referred to as the pulmonary blood flow
Perfusion
Where is the greates perfusion?
Base of the lungs d/t gravity
What is the normal ventilation to perfusion?
V/Q ratio: 0.8 or 80%
Fev1/ FVC ratio: 0.8 or 80%
referred as gas exchange
respiration
External respiration happens between ____ and ____;
Internal respiration happens between ___ and ____
External: alveoli and capillaries
Internal: capillaries and tissues
It is referred to as the inhalataion and exhalation
transport of O2 and CO2
from high to low concentration (a passive process)
Diffusion of O2 and CO2
3 components of URT
upper respiratory tract
- Nose/Nasal cavity
- Pharynx or Throat
- Larynx or voice box
Define NOSE and its function
Definition: large, mucosal (moist) surface area
Function: filters and warms/ humidify air
Describe PHARYNX and what are the 3 divisions of pharynx
aka throat
under respiratory and gastrointestinal system
1. Nasopharynx
2. Oropharynx
3. Laryngopharynx
Function of Larynx aka voice box
a. Voice/sound production
b. Ensures that air will pass through the trachea
the guardians of the airways prevent foreign object pass through the trachea, leaflet structure
Epiglottis
other name for the Lower respiratory tract and how many generations are there?
Tracheobronchial Tree
23 generations
What are the generations of LRT (10)
T, MB, LB, SB, Tb, Rb, AD, AS, A, C
- Trachea (windpipe)
- Mainstem bronchi (R/L)
- Lobar bronchi
- Segmental bronchi
- Terminal bronchioles
- Respiratory bronchioles
- Alveolar ducts
- Alveolar sacs
- Alveoli (structural unit of the lungs) (300M)
- Capillaries
- Most common site of intubation = Trachea
- Tracheostomy – procedure of opening trachea
Passageway of air only; no ga exchange occurs
Conducting zone
Trachea up to terminal bronchioles
functional unit of the lungs
Acinus
Level of division or bifurcation of L/R bronchi
Carina
common resting place for large aspirated objects and reason why
R main Bronchus: shorter, wider and more vertical in orientation
Which lung is common for occurrence of aspiration pneumonia
Right lung
structural unit of lungs
Alveoli
membrae covering the lungs including the fissure lines
Visceral pleura
membrane that covers the thoracic wall
Parietal pleura
Space found between the visceral and parietal
pleural space
Normal pleural space pressure
-4 mmHg
2 function of pleural fluid
lubricate pleurae and shock absorption
What is type I cells
flat cells lining the alveoli
What is type II cells
Synthesizes or secretes “Surfactant”
Surfactant: reduce surface tension of lungs to prevent to collapse
Condition where surfactant is decrease in newborns leading to collapse of small alveoli
Respiratory Distress Syndrome
other name: Hyaline Membrane Disease
Anterior Boundary of lungs
Sternum
aka dagger bone
Posterior boundary of lungs
thoracic vertebrae (12)
Lateral boundary of lungs
how many pairs?
What are their divisions?
Ribs
12 pairs = 24 total
True ribs: pair 1-7 - attached to sternum
False ribs: pair 8-10 - attached to 7th rib
Floating ribs: Pair 11-12 - attached to T11/T12
Muscles involved during
RELAXED INSPIRATION
Diaphragm (Primary)
External Intercostals (Assist)
Muscles involved during Forced Inspiration
Accessory mm of respiration
Sternocleidomastoid (SCM)
Upper trapezius
Pectoralis major/minor
Ant/mid/post scalenes
Serratus Ant/Post. Superior
Boxer’s muscle = Serratus
Muscles involved during relaxed expiration
None. Only elastic or passive recoil od lungs and thorax
Muscles involved during Forced Expiration
Abdominals
Serratus post Inf
Internal intercostals
Arterial Blood Gas (ABG)
pH
7.35 - 7.45
Arterial Blood Gas (ABG)
PACO2
*Partial pressure of CO2
35-45 mmHg
Arterial Blood Gas (ABG)
PAO2
Partial pressure of O2
80-100mmHg
Arterial Blood Gas (ABG)
HCO3
Bicarbonate
22-26 mEq/L
Arterial Blood Gas (ABG)
SAO2
Oxygen Saturation
95-100%
inversely or directly
pH is ____ related to PACO2
*Respiratory
Inversely
inversely or directly
pH is ____ related to HCO3
Metabolic
Directly
RESPIRATORY: Alkalosis or Acidosis?
increase pH = decreased PACO2
Alkalosis
RESPIRATORY: Alkalosis or Acidosis?
decreased ph = incresed PACO2
Acidosis
Metabolic: Alkalosis or Acidosis?
decreased ph = decreased HCO3
Acidosis
Metabolic: Alkalosis or Acidosis?
increased pH = increased HCO3
Alkalosis
Identify cause of Respiratory Acidosis
*Cayetano Jingle
COPD
Atelectasis
Respiratory failure
Pneumonia
Asthma
CARPA CARPA CARPA RESPI ACI – ACIDOSIS!
Causes of Metabolic Acidosis
- Don’t stop the music song
DM- Ketoacidosis
Diarrhea
Renal Failure
D, D RENAL FAILURE (2X)
D, D, RENAL (3X)
KETOACIDOSIS MAC MAC
Causes of Metabolic Alkalosis
*Voltes 5 theme
Vomiting
Antacids
Nasogastric suction
Diuretics
Excessive bicarbonate ingestion
Causes of Respiratory Alkalosis
- Binibirocha
Hypoxemia
Hyperventilation
Ventilator
Pain
HYPOXCEMIA, HYPERVEN, VENTILATOR TSAKA PAIN.
CAUSES NG RAL SYA (2x)
amt of air that can be contained inside the lungs after a maximal inspiration
TLC
total lung capacity: 6000mL
amt of air that can be maximally expired after a maximal inspiration
VC
Vital capacity: 4500mL
amt of air left/remained inside the lungs after a max or forceful expiration
RV
Residual volume: 1500mL
amt of air that can be maximally inspired in after a Normal expiration
IC
Inspiratory Capacity: 3500mL
amt or remain of air inside lungs after Normal expiration
FRC
Functional Residual Capacity: 2500mL
Amt. of air that can still be expired after N expiration
ERV
Expiratory reserve volume: 1000mL
amount or volume of air amount or volume of air inspired or expired with each normal breath
TV
Tidal volume
amount or volume of air amount or volume of air inspired or expired with each normal breath
TV
Tidal volume: 500mL
amt or vol of air that can still be inspired in after Normal inspiration
IRV
Inspiratory reserve volume: 3000mL
Lung volumes and capacity that cannot be measured using a Spirometer
RV
FRC
TLC
Devise used to measure RV, FRC, TLC
Helium/Nitrogen wash out
Body Plethysmography