pulmonary 3

Question 1

what is sarcoidosis

Answer 1

idiopathic chronic multi systemic inflammatory non-caveating granulomatous disease

Question 2

RF for sarcoidosis

Answer 2

females
black americans
Northern Europeans
20-40 y

Question 3

sx sarcoidosis

Answer 3

50% asx
pulmonary - dry cough, dyspnea, rales, may have chest pain
lymphadenopathy (swelling of lymph nodes)
skin - erythema nodosum (classic), lupus pernio (most specific)
eyes - anterior uveitis, dry eyes, vision loss
cardiac - cardiomyopathy, arrhythmias, heart blocks
rheumatologic - arthralgias, fever, malaise, wt loss
neurologic - cranial nerve palsies esp facial nerve, diabetes insipidus

Question 4

what is Lofgren syndrome

Answer 4

associated w sarcoidosis
triad of erythema nodosum + bilateral hilarity lymphadenopathy + polyarthralgia w fever

Question 5

dx sarcoidosis

Answer 5

CXR
PFTs
Tissue biosy
Labs

Question 6

what will CXR show for sarcoidosis

Answer 6

best initial test
bilateral hilar lymphadenopathy classic

Question 7

what will PFTs show for sarcoidosis

Answer 7

restrictive pattern classic
normal or increased FEV1/FVC
decreased lung volumes - RV, FRC, TLC
decreased DLCO

Question 8

what will tissue bx show for sarcoidosis

Answer 8

noncaseating granulomas

Question 9

what will labs show for sarcoidosis

Answer 9

increased ACE levels
hypercalciuria
hypercalcemia
increased vitamin D

Question 10

tx for sarcoidosis

Answer 10

asx - observation
sx - oral corticosteroids

Question 11

different stages of sarcoidosis (you determine staging from CXR)

Answer 11

stage 1 - b/l hilar adenopathy
2 - b/l hilar adenopathy + interstitial lung disease
3 - interstitial lung disease only
4 - fibrosis (restrictive dz)