Pulmo interstitial lung disease Flashcards
Finding:
spontenous pneumothorax
PLCH
tuberous sclerosis
LAM
neurofibromatosis
Finding elevated aCE
sarcoidosis
Finding:
substernal discomfort
sarcoidosis
Finding:
wheezing
Chronic eosinophilic pneumonia
Churg strauss syndrome
reapiratory bronchitis
sarcoidosis
Familial lung fibrosis gene mutations
- surfactant protein C gene
- surfactant protein A2 gene
- ATP binding casette transporter A3 gene
Bronchoalveolar lavage finding:
Sarcoidosis
Lymphocytosis
CD4:CD8 ratio >3.5 most specific
Bronchoalveolar lavage finding
HYPErSENSITy Pneumonitis
Marked lymphocytosis> 50%
Bronchoalveolar lavage finding
ORGANIZING PNEUMONIA
foamy macrophages
mixed cells
Cd4 cd8 ratio decreased
Bronchoalveolar lavage finding
EOSINOPHILIC LUNG DISEASE
eo > 25
Bronchoalveolar lavage finding
PULMONARY LANGERHANS CELLS HISTIOCYTOSIS
increased cD1 positive langerhands cells
EM: birbeck granules in lavaged macrophage
Bronchoalveolar lavage finding
ASBESTOS RELATED PULMO DSE
Dust particles
ferruginous bodies
Bronchoalveolar lavage finding
beryllosis
(+) lymphocyte transformation test to beryllium
First described in coal miners, found in patients with silicosis
(+) seropositive rheumatoid arthritis with characteristic pneumoconiotic nodules
Caplan’s syndrome