Pulm- FC Flashcards
Where is nocireceptor for delivering pain in embolism
parietal pleura
: intercoastal nerves and phrenic nerves innervated parietal pleura
- There is NO visceral nerve innervation in visceral pleura
Histologic finding of Kulchitsky cells: What lung cancer is this?
small cell lung cancer
*Kulchitsky cells is another term for neuroendocrine cells
What is value of I/E in spirometry? How is this value affected in COPD?
I/E: Inspiration time/ Expiration time
I/E value goes down in COPD due to increased expiration time
What happens to type 1 and type 2 pneumocytes in ARDS?
destructed due to inflammatory infiltrates
What happens to ventilation, perfusion, diffusion in ARDS?
decreased ventilation: collapsed alveoli
~normal perfusion:
decreased diffusion: alveolar hyaline thickness
- think perfusion as air spreading out through alveoli
Anti-histamine overdose effect on skin?
Dry and flushing
Antihistamine overdose -> anti-muscarinic effect
-> decreased sweating (sympathetic innervation releases Ach on muscarinic receptor on sweat gland: this is one of few exceptions of sympathetic innervation)
-> flushing (no way to get the heat out, usually heat is dissipated by sweating) and dryness
Explain why addition of inhaled glucorcorticoid in pre-existing albuterol therapy is helpful for asthma
inhaled glucorcoticoid
-> more beta receptors: more B2 agonist effect by albuterol
- like cortisol, glucorcoticoid can increase B agonist sensitivity
Which portion of airway is affected in bronchiectasis?
bronchi
- I thought it is respiratroy bronchioles, but remember bronchiectasis is huge. So it must happen exclusively at brochi
Which portion of airway is affected in asthma?
bronchi
- Rule of thumb: All COPD affects ONLY BRONCHI except emphysema (which affects alveoli)
From which cranial nerve is reccurent laryngeal branched off?
Vagus
