Pulm

Question 1

what is released from hemoglobin during oxygenation of Hb?

Answer 1

H+ ions (will decreased pH); this will help convert HCo3- to make bicarb (which can convert to CO2 and H2O)

Question 2

haldane effect (2 consequences) with binding of O2 to hemoglobin

Answer 2

1. affinity for Co2 decreased, resulting in unloading of CO2 from hemoglobin
2. acidity of hemoglobin in increased; protons are released from hemoglobin binding sites

Question 3

Aspergillus fumigatus is what type of infection? See commonly in what types of patients?

Answer 3

opportunistic fungal infection; seen in asthmatic and cystic fibrosis patients; may cause bronchietasis and eosinophilia

Question 4

even is pathologic conditions (ie pulmonary fibrosis)..what is the difference between CO2 and O2 gas exchange?

Answer 4

CO2 diffusion occurs 20 times faster than O2; capillary and alveolar CO2 pressures fully equilibrate while O2 does not.

O2 diffusion is greatly impaired in pathologic conditions

Question 5

lung abscess formation predominantly mediated by what cell type?

Answer 5

neutrophils

Question 6

exacerbations of COPD are caused by worsening of underlying inflammation and are most often triggered by what type of infections?

Answer 6

viral or bacterial respiratory infections (ie rhinovirus)