Pulm Flashcards
3 subjective findings in ARDS (As)
Acute dyspnea
Anxiety/agitation
Air Hunger
patho phys of ARDS
alveoli damage
increased permeability to alveolar/cap membrane
cytokine increase
surfactant/compliance decrease
3 clues on CXR for ARDS
bilateral infiltrates
no clear diaphragmatic borders
white out
ARDS BERLIN diagnostic & range
Dx ARDS
Pa02/FiO2
200-300 mild
100-200 moderate
<100 severe
Tx of ARDS with mechanical ventilation
FiO2 <65%
lower TV for PIP <30
avoiding high PEEP
WHAT TYPE OF RESP FAILURE
PaO2 =/< 60mmHg
Inability to adequately oxygenate blood
oxygenation defect
Hypoxemic
acute lung injury, pulm edema, pneumonia, and R to L shunt without oxygen is a cause of what
hypoxemic resp failure
WHAT TYPE OF RESP FAILURE
PCO2 >50mmHg
inability to clear CO2
Ventilation defect
Hypercapnic Respiratory failure
obstructive disease, neuromuscular disease, central respiratory drive failure are all causes of what?
Hypercapnic respiratory failure
WHAT TYPE OF RESP FAILURE
hypoxemic (<50) and hypercapnic (>60)
mixed respiratory failure
what vent management helps with ventilation
Respiratory rate and tidall volume for CO2 removal
what vent management helps with oxygenation
FiO2 and PEEP
removal of CO2
ventilation
delivery of oxygen to tissue
oxygenation
how much pressure to hold alveoli open
PEEP
total pressure required to overcome airway resistance of elastic properties of chest/wall
peak pressure
pressure required to over come elastic recoil of lungs
plateau pressure
Peak pressures should be ______
Plateau pressures should be _____
PIP 35-40
Plateau: <30
helps overcome resistance of vent circuit/tubes
pressure support
Increasing what 2 vent measures will decrease CO2
TV and RR
indications for intubation
airway protection
resp failure
increased WOB
need for sedation/paralysis
decreased FEV1/FVC ratio =
obstructive
reduced FVC with normal FEV1/FVC ratio =
restrictive
easy tool for seeing if obstructive vs restrictive
plain spirometry
lungs have difficulty EXPANDING; decrease in lung volumes (problem getting in)
Restrictive
difficulty in air flowing OUT of lungs; decrease air flow & cant get out
Obstructive
amount of air remaining in lungs after MAX expiration
residual volume (RV)
total air exhaled quickly after inhaling max volume
forced vital capacity (fvc)
amount of air expired during forced vital capacity (FVC) portion of the test but measured in seconds
forced expiratory volume (fev1)
after spirometry with bronchodilator; what result will you see with asthma
full return to normal FEV1
partial improvement with bronchodilator spirometry may indicated
COPD; bronchiolitis
CAP is typically in regular community (adeno, corona)
what are some bacterias?
TYPICAL
ATYPICAL
Typical: step pna, h. influenzae, moraxella
Atypical: legionella, mycoplasma, chlamydia
CAP treatment for
healthy:
comorbidities:
healthy: macrolide (azithromycin) or doxycycline
comorbidities: levaquin, beta-lactam (augmentin plus azithromycin)
NON ICU management for CAP
change IV beta-lactam to ceftriaxone or ertapenemenand IV/PO fluoroquinolone
ICU management for CAP
IV beta-lactam PLUS azithromycin or fluoroquinolone
Pseudomonos CAP abx
zosyn, cefepime, imipenem, meropenem
MRSA or likely hood for CAP abx
vanc or linezolid
HAP bugs
LARGE causes: staph aureus, strep pneumo, pseudomonas, gram - bacilli
HAP abx coverage
High MRSA: vanc or linezolid
low mortality: zosyn, cefepime, levaquin, imipenem, meropenem
pseudomonas: aztreonam
pseudomonas coverage for PNA
Zosyn, cefepime, imipenem, meropenem
Can add aztreonam
MRSA + PNA abx
vanc or linezolid
HAP & VAP occur when
48 hours after admit/intubation
inflamed/irritated airway that swells and narrows
asthma
asthma is what type of airway disease
restrictive (restricting air from entering)
3 types of asthma
- allergy induced
- occupational exposure
- exercise induced
asthma is highest in what population and economic status in USA
african american / lower socioeconomic status
3 subjective findings of asthma
- dyspnea
- chest tightnesss
- cough/wheeze
reduced air inhalation sounds
expir wheezing
is an example of
asthma
severe asthma exasterbation of asthma could have what.2 exam findings
minimal breath sounds
use of accessory muscles
PFT: reduced FVC with normal/increased FEV1/FVC ratio
ASTHMA
> 12% increase in FEV1 or FVC post bronchodilator therpay is an indicator of
asthma
& bronchodilator responsiveness
symptoms <3days/week and <2 awakenings/month = intermediate asthma
patient just needs a rescue/ SABA
biggest difference mild persistant versus intermediate asthma is
> 2 days/week and >2 days awakening/month
low dose ICS and SABA PRN
when do you intubate an asthmatic patient (3)
no breath sounds; fatigue; AMS
patients at this stage need to see a specalist and consider biologics (xolair)
STEP 5 SEVERE PERSISTANT
systemic miliary TB can cause several multi system organ issues such as
sterile pyuria ( high wBC in urine) meningitis pott disease (lumbar vertebrae) addisons disease hepatitis lymphadenitis in neck
testing for TB includes
PPD (skin test) (exposure at some point)
IGRA (exposure; more specific)
CXR
symptoms of TB
fever
night sweats
weight loss
hemoptysis
Latent TB is treated with
isoniazid
active TB drugs
Rifampin
Isoniazid
Ethambutol
Purazinamide
drug resistant TB strains
MDR-TB
XDR-TB
4 causes of pneumo
spontaneous
trauma
iatrogenic (line placement)
pathology
dx of pneumothorax
no lung markings on XR
line through lung
pneumo management: no treatment guidelines
no SOB & <2cm
follow up CXR
pneumo management: treatment guidelines
SOB / > 2cm
aspiration x 2
then chest drain
trauma to the chest wall that creates a one way valve lets air in and doesnt let air out of pleural space
tension pneumo
WHAT AM I tracheal deviation decreased air entry increased resonance increased hemodynamic instablity (tachy, low BP)
tension pneumo
tension pneumo treatment
insert a large bore cannula into the 2 ICS in the mid clavicular line
- way for air to get out
- dont wait
3 land marks for CT insertion
-triangle of safety-
5th ICS
Mid-Axillary line
Anterior Axillary line
difficulty breathing, fatigue, weakness, chest pain, dizziness, and syncope are initial symptoms of what
PAH
disorders taht may cause PAH
BMPR2 disorder
scleroderma
left to right heart shunts
portal HTN
be sore to do WHAT when your patient has PAH
test for other underlying causes
most common symptom of a PE
shortness of breath
If a PE is suspected it is best to
act quickly
image
anticoagulate (check contradictions)
indefinite anticoagulation should include
patients with unprovoked PE, persistent risk facts, & repeat PEs
pleuritic chest pain, hemoptysis are s/s of what PE
infarction
hypoxemia, hypocpapnia, resp aklalosis s/s of
PE and abnormal gas exchange
RHF symptoms (fatigue, lighthead, SOB) are s/s of what
CV compromise with PE
-IUM are what drugs
LAMA (triotropium/spiriva)
Lowest symptom COPD patients are started on ?
Bronchodilator
Albuterol
-OL ending drugs are
LABAS (sameterol)
Other than bronchodilator, COPD starting drugs are
LAMA
Other than bronchodilator, asthma starting drugs are
ICS
Drugs ending in -ONE
ICS
Medicare home o2 requirements
Pa02 < 60 or Sa02 89% or less