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271- F1 > Pulm 1- SABA/LABA > Flashcards

Pulm 1- SABA/LABA Flashcards

1
Q 
What medication class is albuterol?
Indication? MOA? SE?
A

Class: SABA
Indication: Acute SOB
MOA: Stimulates B2 receptors -> Bronchodilation
SE: tachycardia, HypoK (esp. if continuous)

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2
Q

What medication class is Levalbuterol (Xoponex)? Indication?

A

Class: SABA
Indication: Acute SOB
MOA: Stimulates B2 receptors -> Bronchodilation

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3
Q 
What medication class is Metaproterenol (Alupent®)?
Indication? MOA? SE?
A

Class: SABA
Indication: Acute SOB
MOA: B2 Agonist
SE: Palpitations, Tachycardia, HypoK, Tremor, HA, N

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4
Q 
What medication class is Pirbuterol (Maxair®)?
MOA?
A

Class: SABA
MOA: B2 agonist

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5
Q 
What class is Terbutaline (Brethine®)?
Indication? Contraindication?
A

Class: SABA, Tocolytic

Not for children

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6
Q

What is the most important general consideration when prescribing a LABA?

A

Not for monotherapy

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7
Q

What class is Salmeterol DPI (Serevent Diskus)? MOA? Duration/onset?

A

LABA- B2 partial agonist
Onset 30 min
Duration: 12 hours

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8
Q 
What class is Formoterol DPI (Foradil)?
MOA? Indication? SE?
A

LABA- B2 Agonist
Useful for noc sx
Not for acute bronchospams
Can cause paradoxical bronchospasm

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9
Q 
What class is Arformoterol (Brovana®)?
SE? Contraindications?
A

LABA- B2 agonist
** Paradoxical bronchospasm
More powerful enantiomer of Formoterol
SE: Palp, tachy, tremor, N, HA

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10
Q 
What class is Indacaterol (Arcapta®)
SE? Contraindications?
A

LABA- B2 agonist
** No peds
Similar SE to other LABA

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11
Q 
What class is Olodaterol (Striverdi Respimat®)?
Contraindication?
A

LABA- B2 agonist
DDI: 2C9 substrate
T1/2= 45 hours

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12
Q 
What class is Albuterol + ipratropium bromide (Combivent Respimat)?
MOA?
A

SABA, Corticosteroid
B2 agonist
Muscarinic antagonist-> bronchodilates

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13
Q 
What class is Fluticasone/Salmeterol (Advair®)?
SE?
A

LABA, corticosteroid

Potentiates 3A4 inhibitors: increases salmeterol -> QT prolongation

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14
Q 
What class is Fluticasone/Vilanterol (Breo Ellipta®)?
SE?
A

LABA, corticosteroid

Potentiates 3A4 inhibitors: increases vilanterol -> QT prolongation

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15
Q 
What class is Budesonide/Formoterol (Symbicort®)?
SE?
A

LABA, corticosteroid

SE: Thrush, dysphonia, pharyngitis, HA, tremor, N

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16
Q 
What class is Mometasone/Formoterol (Dulera®)?
SE?
A

LABA, corticosteroid

SE: Similar to others in class

17
Q

What class is Albuterol/Ipratropium (Combivent Respimat®)[Duoneb]
SE?
Contraindication?

A

SABA, anticholinergic
SE: **Paradoxical bronchospasm, palp, tachy, tremor
Contraindicated in pts with soy/peanut allergy

18
Q 
What class is Vilanterol/Umaclidium?
Notes?
A

LABA + Anti-Cholinergic

3A4, 2D6 inducers

19
Q 
What class is Olodaterol/Tiotropium?
Indication?
A

LABA + Anti-Cholinergic
COPD maintenance
Not for asthma

20
Q

What class is Formetorol Furmate/Glycopyrrolate
(Bevespi Aeorosphere)?
T1/2?

A

LABA + Anti-Cholinergic

T1/2 = 53 hours

21
Q 
What class is Indacaterol/Glycopyrrolate
T1/2?
A

LABA + Anti-Cholinergic

33-53 Hours

271- F1 (7 decks)

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