Public Heath Flashcards

1
Q

Causes of associations

A

Bias
Chance
Confounding
Reverse causality
True association

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2
Q

Define bias?
Selection bias?
Types of information bias? (4)
Publication bias?

A

Definition: A systematic error that results in a deviation from the true effect of an exposure on an outcome
Selection bias- Selection of study population eg. Non response of certain groups, loss to follow up of certain groups
Allocation bias e.g. different participants in the groups

Information bias (MORR) -
Measurement bias (different equipment measures things differently)
Observer bias- Observer’s expectations influence reporting
Recall bias- Past events not remembered or recalled correctly
Reporting bias- Respondent doesn’t report the truth because they feel ashamed/judged

Publication bias- Trials with negative results less likely to be published
Drug trials more likely to be published if sponsored by drug company

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3
Q

What are the brad ford hill criteria for causation ?

A

STD R Crap

Strength - very high relative risk (Relative Risk of 21)

Temporality - most important - exposure occurs before outcome (people smoke before developing lung cancer

Dose-response - more risk of outcome with more exposure (the more you smoke the higher the risk of lung cancer)

Reversibility - if you take away the exposure then the risk of disease decreases or is eliminated (stop smoking and you have a decreased risk of lung cancer after 10 years or so)

Consistency - the association is seen in different geographical areas, using different study designs, in different subjects (smoking is associated with lung cancer in dogs, mice and people, all over the world)

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4
Q

2 pros and 2 cons of RCT ? What is it/>

A

😍 Low risk of bias and confounding
😍 Can infer causality
😒 Time consuming and expensive
😒 Unrepresentative study population

Similar participant are randomly assigned to an intervention or control group

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5
Q

Case control basics? 2 pros 2 cons?

A

Observational study looking at cause of a disease. Compares similar participants with disease and controls without.
Looks retrospectively for exposure/cause
😍 Quick (as outcome has already happened)
😍 Good for rare outcomes (e.g. cancer)
😒 Difficult finding appropriately matched controls
😒 Prone to selection and information bias

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6
Q

Cross sectional basics? 2 pros / cons?

A

Observational study collecting data from a population and a specific point in time.
A snapshot of a group e.g. census or patient survey
😍 Large sample size
😍 Provides data on prevalence
😒 Risk of reverse causality- which came first?

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7
Q

What is reverse causality?

A

Outcome may have caused the exposure
Eg survey on whether depressed people are obese -which caused which

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8
Q

Cohort basics? Pros? Cons?

A

Longitudinal study in similar groups but with different risk factors/treatments. Follows them up over time
E.g. Framingham Heart Study or smoking doctors vs non-smoking doctors
😍 Can follow up rare exposure e.g. natural disaster
😍 Allow identification of risk factors (exposure causing outcome)
😒 Takes a long time, people drop out
§

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9
Q

Over a ten year period, there were 50 cases of lung cancer in Crookes (a population of 1,000 people).

What is the incidence (risk) of lung cancer per year?

A

(50/1000)/10 = 0.5%/ year

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10
Q

In Crookes (a population of 1000 people), 300 of them smoke. Of those who do smoke, 45 of them developed lung cancer. 5 of the non-smokers developed lung cancer.
What is the relative risk of lung cancer in smokers?

A

Risk in exposed = 45/300 = 15%

Risk in unexposed = 5/700 = 0.7%

Relative risk (risk ratio) = 15/0.7 = 21.4 times more likely to develop lung cancer if you smoke compared to non smokers

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11
Q

In Crookes (a population of 1000 people), 300 of them smoke. Of those who do smoke, 45 of them developed lung cancer. 5 of the non-smokers developed lung cancer.
What is the risk of lung cancer that is attributable to smoking?

A

Risk of lung ca in exposed = 45/300 = 15%
Risk of lung ca in unexposed = 5/700 = 0.7%

Attributable risk = (15/100)- (0.7/100) = 14.3

Attributable risk is the number of cases that are due to smoking so you take away the naturally occurring cases (“that would happen anyway”)

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12
Q

In Crookes (a population of 1000 people), 300 of them smoke. Of those who do smoke, 45 of them developed lung cancer. 5 of the non-smokers developed lung cancer.
How many people would have to give up smoking to prevent one death from lung cancer?

A

Attributable risk = (15/100)-(0.7/100) = 0.143

NNT = 1/AR

= 1/0.143 = 6.99

So if 7 people stopped smoking you would prevent 1 death due to lung cancer in this population

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13
Q

Define sensitivity? Specificity ? PPV? NPV? And how to work out?

A

Sens - % correctly identified with disease (associated with increased false positives) a/(a+c)

Spec - %correctly excluded as not having the disease (low causes unnecessary follow ups) d/(b+d)

Positive predictive value= % of those with a positive test that actually have the disease a/(a+b)

Negative predictive value= % of those with a negative test who are actually disease free d/(c+d)

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14
Q

What is the Wilson screening criteria

A

INASEP

Important disease
Natural history of the disease must be understood e.g. detectable risk factors, disease marker
Simple, safe, precise and validated test
Acceptable to the population
Effective treatment from early detection with better outcomes than late detection
Policy of who should receive treatment

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15
Q

Disadvantages of screening

A

Over detection of sub clinical disease
Needless worry if the screening result comes back positive and/or exposure to harmful diagnostic tests e.g. colonoscopy after faecal occult blood.
Is this higher in low sensitivity of low specificity? Answer= low specificity!
Over-identification and treatment of sub-clinical and harmless disease.
Harm from the screening test or subsequent treatment e.g. antibiotic resistance in GBS pregnant women

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16
Q

lead time vs length time bias ?

A

Lead time bias= Early identification doesn’t alter outcome but appears to increase survival
e.g. patient knows they have the disease for longer
Length time bias= Disease that progress more slowly is more likely to be picked up by screening (i.e. symptom free and around for longer), which makes it appear that screening prolongs life.

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17
Q

Mnemonic for health inequality ?

A

PROGRESS
Place of Residence (rural, urban, etc.)
Race or ethnicity
Occupation
Gender
Religion
Education
Socioeconomic status
Social capital or resources

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18
Q

Definition of health
Key articles of human rights act of 1998

A

Definition of health: a state of complete physical, mental and social wellbeing. No merely the absence of disease or infirmity

Article 2 – right to life
Article 3- right to freedom from inhuman and degrading treatment
Article 8- right to respect for privacy and family life
Article 12- right to marry and found a family
Article 14- right to freedom from discrimination

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19
Q

Causes of errors

A

Sloth error – being lazy, not bothering to check results/ information for accuracy. There is incomplete evaluation.- improved by paying attention to detail, and checking information

Lack of skill – lack of appropirate skills teaching or practice- improved by being properly trained in your role and PPD!

Communication breakdown – unclear instructions or plans and not listening to others- improved by being approachable and listening.
System failure
Human factors
Judgement failure
Neglect
Poor performance
Misconduct

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20
Q

4 parts of negligence ? What is bolam ? Bolitho?

A

Was there a duty of care?
Was there a breach in that duty?
Was the patient harmed?
Was the harm due to the breach in care?

Bolam - Would a group of reasonable doctors do the same?
Bolitho - Would that be reasonable?

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21
Q

What are the 3 domains of public health?

A

Health improvement
Social interventions and preventing disease, promoting health and reducing inequalities

Health protection
Measures to control infectious disease risk and environmental hazards

Improving services
Organization and delivery of safe high quality services

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22
Q

What is the health needs assessment?

A

Is a way of systematically reviewing health issues to find a list of agreed priorities and resource allocations that will improve health and reduce inequalities

Needs assessment -> planning -> implementation -> evaluation -> repeat

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23
Q

What is the Bradshaw taxonomy of need? (4 types of need)

A

Felt need- individual perceptions
Feeling back pain

Expressed need- individual seeks help (demand)
Going to the Dr with back pain

Normative need- professional defines intervention
GP decides you need a physio

Comparative need- comparison
Compare all the referrals from GP X to physio to GP Y

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24
Q

What are the 3 approaches to HNA?

A

Epidemiological
Defines the problem and looks at the size of it using routine and primary data

Comparative
Looks at services received and compares with a similar area – may compare health outcomes

Corporate
Asks the local population and health profs what the needs are using focus groups etc

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25
Pros / cons of epidemiological approach to HNA
pros Uses existing data Provides incidence mortality and morbidity data Can evaluate services by trends over time Cons Quality of data is vsriable Data collected might not be the data required Doesn’t consider the felt needs or opinions of those its looking at
26
Pros / cons of comparative approach to HNA
Comparative Pros Quick and cheap if data available Indicates whether services are better or worse in comparable areas Cons Difficult to find a comparable
27
Pros / cons of corporate approach to HNA
Corporate Pros Based on felt and expressed needs Recognises the knowledge and experiances of those working in the population Takes into account a wide range of views Cons Difficult to establish need from demand Groups may have vested interests May be influences by political agendas
28
3 types of health behaviour
Health behaviour Prevent disease E.g go for a run, wear sun screen etc Illness behaviour Going to the DR Sick role behaviour Taking medications
29
3 types of behaviour change
Transtheorectical model- Pre contemplation- not ready yet Contemplation Preparation Action Maintenance / relapse Nudge – nudge the environment for positive change – fruit near the checkouts Theory of planned behaviours – best predictor of change is intention Persons attitude to the behaviour (smoking is bad) Subjective norms- percieved social pressures/norms (GP wants me to give up) Perceived behaviours – how well the person thinks they can do it (I can do it!!)
30
What 3 principles is resource allocation based on?
Egalitarian Based on the idea that the NHS was founded on the requirement to provide all care that is necessary and required to everyone Equal for everyone Maximising Maximise public utlity/ profits? – an act is evaluated soley in terms of its consequences – will it be beneficial? Give to those who it is most likely to benefit the most Libertarian Each is responsible for their own health The german health incentive scheme – change health behaviours and get bonuses for partipating
31
What are never events? What do they lead to? Egs?
Serious, largely preventable patient safety incidents that should not occur if the available preventative measures have been implemented Financial penalties, affect trust reputation, CQC visits Surgical - wrong site / retained foreign object Psych - escape of a transfer pt Medical - wrong route of chemo administration / opioid overdose
32
A group of patients with lung cancer and a group of age matched controls are compared by looking at pack life history to assess the impact of smoking on lung cancer. What type of study is this? Give an example of a covariate? What type of bias may interfere with results?
Retrospective case-control E.g. work exposure, gender, type of tobacco, level of passive smoking Selection bias e.g allocation bias (inappropriately matched controls) and information bias e.g. recall and reporting bias
33
3 benefits of cohort studies
Identify causation Ethical assessment of RF (if exposure was thought to be dangerous would not be fair to do a RCT ) Allows assessment of multiple risk factors
34
A new diagnostic test is being developed: 100 people known to have the disease are tested as are 200 disease-free controls. Ninety of the cases yield positive tests, as do 30 of the controls. What is the specificity of the test? What is the positive predictive value? What do these mean?
85% 75% 85% specific means 85% of people without the disease were correctly excluded. 75% PPV means of those who had a positive result, 75% actually had the disease.
35
Why do you notify public health
So HPA can take control measures You may be the only one to tell them Duty of registered medical practitioners
36
Role of the consultant in communicable disease control
Surveillance - Notification / lab data to monitor diseases Prevention - Eg vaccination Control
37
Basics of outbreak management
Clarify problem - make a diagnosis Decide if its an outbreak - 2 or more related cases Gain help - microbiologist, consultant in infectious disease, health visitors Call an outbreak meeting Identify cause Control measures
38
4 causes of homelessness
Relationship breakdown Domestic abuse Dispute with parents Bereavement
39
Health problems faced by homeless
Infectious disease Foot and teeth health Resp problems Violence / rape Sexual health Mental illness Nutrition Addiction
40
Barriers to healthcare for travellers
Reluctance of GPs to register them Illiteracy Communication difficulties Lack of permanent site Mistrust of professionals
41
Barriers to healthcare with homeless
Access -Location / discrimination Lack of integration between primary care and other agencies -housing, social services, criminal justice Other things on mind -don’t prioritise health May not know where to find help
42
What is an asylum seeker, refugee, humanitarian protection?
AS- someone who has made application for refugee status R- granted asylum - usually lasts 5 years HP - failed to get asylum but serious threat if returned - usually lasts 3 years
43
Asylum seekers get?
Vouchers to live off NASS support package Access to NHS Not allowed to work No choice where they go
44
Physical / mental health with asylum seekers ?
Common illnesses / those specific to country Injuries from war / travelling Lack of health screening / immunisations Malnutrition Abuse Untreated chronic disease Communicable disease Mental -PTSD Depression Psychosis Self harm
45
Why is safety compromised in healthcare?
Complexity Resource intense Shared responsibility
46
Error classification based on Intention? Action? Outcome? Context?
I - failure of planned action to achieve desired outcome -skill based -rule based - didn’t follow rules -knowledge based Action -task specific - eg wrong vessel -Generic factors - Eg wrong order / omission Outcome -Near miss / death Context -Interuptions, team factors
47
2 perspectives of error? And cons
Person approach -error due to individual, focuses on the unsafe act -Anticipation of blame -> cover up System -Errors are due to many factors
48
Strategies to reduce errors
Simplification and standardisation of clinical practice Checklists IT Team training Risk management programs
49
Tools of risk identification
Incident reporting Complaints and claims Audits External accreditation Active measurement
50
What is a never event
Preventable patient safety incident which should not occur
51
4 parts of negligence
Is there a duty of car? Is there a breech of this duty Did the patient come to harm Did the breach cause the harm
52
Negligence, why do things go wrong?
System failure Human factors -Personal Teamwork Environment Judgement failure -Analytical / intuitive -defective decision making Neglect Poor performance Repeated small mistake Misconduct
53
Benefits of teaching diversity
Better outcomes for patients -doctors identify their problems more accurately -better patient adherence More satisfying patient encounters -more Effcient time spending -patients more satisfied
54
Benefits and risks of social media
Benefits -Esablish good networks -enagange in debates -improve patient access to services Risks -Loss of personal privacy -potential breaches of confidentiality -risk of posts being reported
55
GMC duties of a doctor
Make the care f your patient your first concern protect and promote the health of the public Provide a good standard of practice and care Treat patients as individuals and respect their dignity Work in partnership with patients Be honest and open and act with integrity
56
Relative risk reduction?
Risk unexposed - risk exposed All over unexposed
57
Name 3 things you can offer a newly presenting drug user
Health check Screening for BBVs Contraception Smear Immunisation Information on drug services Eg needle exchange status
58
Principles of addiction treatment
Harm reduction -Advice on risky behaviour -BBV advice -Testing 0contraception Brief intervention -Explain risks / effects -advice on controlled use -setting limits -cognitive based approaches Team working -referral to sexual health -referral for specialist advice
59
Aims of treatment for drug use
Reduce harm to user, family and society Improve health Stablise lifestyle Reduce crime
60
What is domestic abuse
Any pattern of controlling, threatening, or violence / abuse between those aged 16 and over who may have been family members or intimate partners
61
Domestic abuse impact on health
Trauma Somatic problems - Headche, GI, chronic launch , LBW / premature Psychological / psychosexual -PTSD, suicide, -depression, anxiety, eating disorder -Substance misuse
62
Role of doctor in Domestic abuse
Healthcare records important in court Display helpline and give contact cards Focus on patients safety Ask direct questions Be non judgemental
63
Risk levels and what should you do for DA ?
Standard - evidence does not suggest likelihood of causing serious harm Medium - Identifiable indicators of risk of serious harm -Unlikely to happen without change in circumstance ->Give DA abuse contact details High - Risk of imminent harm -> Refer to -MARAC (multi-agency risk assessment conference) - Identifies risk and provides appropriate services -IDVAS - supports women (a voice for MARAC) -DHR - Domestic homicide review - if death of a persons aged over 16 and related to violence
64
What tool can be used to assess risk in DA
DASH Domestic, abuse, stalking, harassment
65
How do you assess health equity ?
Inequality is assessed and must be explained to decide if its inequitable Equality may not always be equitable
66
Need, demand and supply in terms of HNA
Need - Ability to benefit from an intervention Demand - What people ask for Supply - What is provided
67
What is positive and negative conditioning in relation to addiction
Positive - increased intensity of desire to use Negative - do not quit as poor experiences Eg nausea
68
What are the comps of drug use
Physical Injection complications Overdose BBV Side effects Eg constipation Social Criminal acts Social exclusion Poverty Psychological Guit Cravings
69
Legal level of alcohol to work in NHS / drive
80mg%
70
3 features of Alcohol dependent syndrome
Need 3 features Tolerance Withdrawal Neglect of other activities Spending more time Continued use despite negative effects Failure to control use CANT STOP
71
Triad of wernickes
Ataxia Opthamoplegia Acute mental confusion
72
Drugs for alcohol stopping abuse
Disurfiram Acamprosate - GABA Blocker Naltrexone
73
What 3 parts of evaluations of health servicws
Structure Process Outcome
74
Issues with health outcomes
Time lag Large sample sizes needed Data quality issues
75
Quality of care - maxwell’s dimensions
Effectiveness Efficiency Equity Accessibility Appropriateness Acceptability
76
General framework of evaluation of heath services
Define the service What are the AIMS of the service Framework - structure, process outcome Methodology - Qual / quantitative Results - recommendations
77
Emotional needs in elderly
[PISAA] Security Attention Autonomy Intimacy Part of wider community
78
Theory of planned behaviour factors?
intention - best predictor of change Persons attitude to the behaviour (smoking is bad) Subjective norms- perceived social pressures/norms (GP wants me to give up) Perceived behaviours – how well the person thinks they can do it (I can do it!!) [perceived behaviours are Subjective to Attitudes and Intention]
79
Define Epigenetics – Allostasis – Allostatic load – Salutogenesis – Emotional intelligence
Epigenetics – expression of genome depends on he environment Allostasis – stability through change, our physiological systems have adapted to react rapidly to environmental stressors. Allostatic load – long term overtaxation of our physiological systems leads to impaired health (stress) Salutogenesis – favourable physiological changes secondary to experiences which promote healing and health. Emotional intelligence – the ability to identify and manage one’s own emotions, as well as those of others
80
Name 3 things primary care is for
Preventing illness promoting health working in a primary health team Shared decision making with pts Managing illness over time
81
Name 3 parts of health improvement
o Inequalities o Education o Housing o Employment o Lifestyles o Family/community o Surveillance and monitoring of specific diseases and risk factors
82
Name 2 parts of health protection
o Infectious diseases
 o Chemicals and poisons
 o Radiation
 o Emergency response
 o Environmental health hazards
83
Name 3 parts of improving services
o Clinical effectiveness o Efficiency
 o Service planning
 o Audit and evaluation o Clinical governance Equity
84
Name 3 types of screening
• Population-based screening programmes • Opportunistic screening • Screening for communicable diseases • Pre-employment and occupational medicals • Commercially provided screening
85
Define screening
A process which sorts out apparently well people who probably have a disease (or precursors or susceptibility to a disease) from those who probably do not.
86
What is the prevention paradox
A preventive measure which brings much benefit to the population often offers little to each participating individual
87
2 approaches to prevention
• Population approach – preventative measure eg. dietary salt reduction through legislation to reduce bp • High risk approach – identify individuals above a chosen cut off and treat – eg. screening for high bp
88
Name 4 criteria for screening
• The condition
 o Important health problem o Latent / preclinical phase o Natural history known • The screening test
 o Suitable (sensitive, specific, inexpensive) o Acceptable • The treatment o Effective o Agreed policy on whom to treat • The organisation and costs o Facilities o Costs of screening should be economically balanced in relation to healthcare spending as a whole o Should be an ongoing process
89
Name 2 bias in screening
Lead time bias: When screening identifies an outcome earlier than it would otherwise have been identified this results in an apparent increase in survival time, even if screening has no effect on outcome. Length time bias: Type of bias resulting from differences in the length of time taken for a condition to progress to severe effects, that may affect the apparent efficacy of a screening method
90
What do you use to describe epidemiology of a disease
• Time • Place • Person [Age Gender Class Ethnicity]
91
Calc for incidence rate
(No.of persons who have become cases in a given time period) / (Total person-time at risk during that period)
92
What is attributable risk
The rate of disease in the exposed that may be attributed to the exposure Incidence in exposed - Unexposed
93
What is relative risk
Ratio of risk of disease in the exposed to the risk in the unexposed Risk in exposed / unexposed [Shows strength of association]
94
what is Relative risk reducion
reduction in rate of the outcome in the intervention group relative to the control group 1-Relative risk
95
What is absolute risk reduction
Risk in unexposed – Risk in exposed
96
What is number needed to treat
number of pts need to treat to prevent 1 outcome 1/ARR
97
Name 2 criticisms of theory of planned behaviour
no temporal element lack of direction / causality
98
What is opportunity cost
to spend resources on ONE activity – means a sacrifice in terms of lost opportunity cost elsewhere
99
What is economic efficiency
achieved when resources are allocated between activities in such a way as to maximize benefit (may not be equal/fair distribution) - May save more lives by trading efficiency with equity (i.e. save more lives, but may not be fair)
100
What is an economic evaluation
comparative study of the costs and benefits of health care interventions.
101
2 ways to measure benefit of interventions
QALY Monetary value – how much someone is going to pay in tax/earn natural units” (BP/pain scoref/number of cases detected)
102
Cost benefit vs cost utility analysis
•Cost-utility analysis: outcomes measured in QALYs •Cost-benefit analysis: outcomes measured in monetary units
103
What do we look at with QALYs
Cost of new treatment Effectiveness of new treatment Dominated = cost is positive, but incremental QALYs negative, Dominant = cost negative but incremental QALY positive