Puberty Flashcards
1
Q
Changes during normal puberty
A
Increase in LH from pituitary from increase in GnH from the hypothalamus at night
Pulses stimulate a rise in estradiol levels
2
Q
Precocious puberty
A
Appearance of secondary sex characteristics before the age of 8 in girls
3
Q
Gonadotrophin-dependent puberty
A
HPG axis activated
May be idiopathic
Can be caused by CNS tumour and malformations
4
Q
Gonatadtrophin-independent puberty
A
Presence of pubertal sex steroids
Disorders of the gonads or adrenals
Ingestion of estrogens
Should be managed by paediatric endocrinologist
5
Q
Timing of puberty in girls
A
Between SEs 8.5-13
Average age 12.8
6
Q
Incidence of precocious puberty
A
1:5-10,000
7
Q
History points for precocious puberty
A
Age of onset Details and rate of progression of secondary sex characteristics Family history Neurological symptoms Exogenous steroid administration
8
Q
Examination points for precocious puberty
A
Anthropometric measurements Tanner staging Skin lesions Neurological signs Signs of virilisation
