PTSD & OCD Flashcards

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1
Q

What is PTSD?

A
  • Intense, prolonged, delayed reaction following exposure to an exceptionally traumatic event.
  • Post-traumatic stress disorder (PTSD) can develop in people of any age following a traumatic event, for example, a major disaster or childhood sexual abuse. The person must be involved directly or as a witness
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2
Q

What are risk factors for PTSD?

A
  • Exposure to major traumatic event: examples are professions (armed forces, police, fire services, journalist, doctor) and groups (refugees, asylum seekers)
  • Pre-trauma: previous trauma, history of mental illness, females, low socioeconomic background, childhood abuse
  • Peri-trauma: severity of trauma, perceived threat to life, adverse emotional reaction during or immediately after event
  • Post-trauma: concurrent life stressors, absence of social support
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3
Q

What are symptoms of PTSD?

A

PTSD symptoms must occur within 6 months of the event and can be divided into 4 categories

  • Reliving: flashbacks, vivid memories, nightmares, repetitive and distressing intrusive images
  • Avoidance: avoiding people, situations or circumstances resembling or associated with the events. Inability to recall aspects of trauma
  • Hyperarousal: hypervigilance for threat, exaggerated startle response, sleep problems, irritability and difficulty concentrating
  • Emotional numbing: lack of ability to experience feelings, feeling detached from toher people, giving up previously enjoyed activities and negative thoughts about oneself

Other symptoms: depression, drug or alcohol misuse, anger, unexplained physical symptoms

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4
Q

What is the ICD-10 Criteria for PTSD?

A

(A) Exposure to a stressful event or situation of extremely threatening or catastrophic nature

(B) Persistent remembering of stressful situation

(C) Actual or preferred avoidance of similar situations resembling or associated with the stressor

(D) Either (1) or (2)

  1. Inability to recall some important aspect of the period of exposure to the stressor
  2. Persistent symptoms of increased psychological sensitivity and arousal

(E) Criteria B, C & D all occur within 6 months of stressful event or the end of period of stress

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5
Q

What is the investigations of PTSD?

A
  • Questionnaires: Trauma screening questionnaire, Post-traumatic diagnostic scale
  • CT head: if head injury suspected
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6
Q

What is the management for PTSD if symptoms presents within 3 months of trauma?

A
  • Watchful waiting may be used for mild symptoms lasting <4 weeks
  • Military personnel have access to treatment provided by the armed forces
  • Trauma-focused cognitive behavioural therapy (CBT) or eye movement desensitisation and reprocessing (EMDR) therapy may be used in more severe cases
  • Short term drug treatment may be considered in acute phase for management of sleep disturbance. Following a traumatic event single-session intervention (often referred to as debriefing) are not recommended
  • Risk assessment important to assess risk for neglect or suicide
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7
Q

What is the management for PTSD if symptoms presents after 3 months of trauma?

A
  • Offered course of trauma-focused psychological intervention. 2 options for psychological intervention are CBT and eye movement desensitization and reprocessing (EMDR). The goal of EMDR is to reduce distress in shortest period of time. Form of psychotherapy with one technique involving eye movement to help brain process traumatic events
  • Drug treatments for PTSD should not be used as a routine first-line treatment for adults. Drug treatment considered if (1) little benefit from psychological therapy; (2) patient preference not to engage in psychological therapy; (3) co-morbid depression or severe hyperarousal which would benefit from psychological interventions
  • If drug treatment is used then venlafaxine, phenelzine, sertraline, mirtazapine or amitriptyline should be tried. In severe cases, NICE recommends that risperidone may be used
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8
Q

What is the defintion of OCD?

A
  • Characterised by recurrent obsessional thoughts or compulsive acts or commonly both. Symptoms can cause functional distress or impairment.
  • Associations: depression (30%), schizophrenia (3%), Sydenham’s chorea, Tourette’s syndrome, Anorexia nervosa
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9
Q

What are obsessions and compulsions?

A
  • Obsessions: unwanted intrusive thought, images or urges that repeatedly enter individuals’ mind. They are distressing for the individual who attempts to resist them and recognizes them as absurd and a product of their own mind
  • Compulsions: repetitive, stereotyped behaviours or mental acts that a person feels driven into performing. They are overt (observable by others) or covert (mental acts not observable)
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10
Q

What is the pathophysiology of OCD?

A
  • Biological: related to ↓ serotonin and abnormalities of the frontal cortex and basal ganglia. Genetic contribution as well. Childhood group A beta-haemolytic streptococcal infection may have a role by setting up an autoimmune reaction which damages basal ganglia (PANDAS)
  • Psychoanalytic: filling the mind with obsessional thought to prevent other undesirable ideas from entering consciousness
  • Behavioural: learned and maintained by operant conditioning.
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11
Q

What are risk factors of OCD?

A
  • Most common in early adulthood and equally common in men and women
  • OCD more common in relatives of OCD patient than in general population
  • Developmental factors such as neglect, abuse, bullying and social isolation
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12
Q

What is the ICD-10 criteria for OCD?

A

(A) Either obsession or compulsion present on most days for a period of at least 2 weeks

(B) Obsessions (thoughts, ideas or images) or compulsions (acts) share a number of features, all of which must be present (FORD Car)

  • Failure to Resist
  • Originate from patient’s mind
  • Repetitive and Distressing
  • Carrying out the obsessive thought (or compulsive act) is not in itself pleasurable but reduces anxiety levels

(C) The obsessions or compulsions cause distress or interfere with subjects social or individual functioning usually by wasting time

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13
Q

What are common obsessions and compulsions of OCD?

A
  • Common obsessions: contamination, Fear of harm, excessive concern with order or symmetry, sex, violence, blasphemy, doubt
  • Common compulsions: checking (e.g., gas taps, water taps, doors), Cleaning, Washing, repeating acts (e.g., counting, arranging objects), mental compulsions (e.g., special words repeated in a set manner, hoarding
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14
Q

What are investigations for OCD?

A
  • Yale-Brown obsessive-compulsive scale (Y-BOCS) – 10 item questionnaires with each item graded from 0-4.
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15
Q

How is OCD with mild functional impairment managed?

A
  • Low-intensity psychological treatments (<10 hours of therapist input per patient): cognitive behavioural therapy (CBT) including exposure and response prevention (ERP)
  • If ineffective then offer choice of either a course of an SSRI (either fluoxetine, fluvoxamine, paroxetine, sertraline or citalopram) or more intensive CBT (including ERP)
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16
Q

How is OCD with moderate and severe functional impairment managed?

A

If moderate functional impairment:

  • Offer a choice of either a course of an SSRI (any SSRI for OCD but fluoxetine specifically for body dysmorphic disorder) and more intensive CBT (including ERP)

If severe functional impairment:

  • Offer combined treatment with an SSRI and CBT (including ERP)
  • Clomipramine is an alternative drug therapy and can be combined with citalopram in more severe cases. Antipsychotic can be added in with SSRI or Clomipramine alternatively
17
Q

What is ERP?

A
  • ERP is a psychological method which involves exposing a patient to an anxiety provoking situation (e.g. for someone with OCD, having dirty hands) and then stopping them engaging in their usual safety behaviour (e.g. washing their hands).
  • This helps them confront their anxiety and the habituation leads to the eventual extinction of the response
18
Q

How should SSRI be used in OCD?

A
  • If treatment with SSRI is effective, then continue for at least 12 months to prevent relapse and allow time for improvement. If SSRI ineffective or not tolerated, try either another SSRI
19
Q

What other help can be offered in patients with OCD?

A
  • Psychoeducation, distracting techniques and self-help books can be used
  • Potential suicide risk should be identified, and managed co-morbid depression should be identified and treated
20
Q

What is Adjustment Disorder?

A
  • Identifiable (non-catastrophic) psychosocial stressor (e.g. redundancy, divorce) within one month of onset of symptoms.
  • Symptoms are variable but can be the types found in affective disorders or neurotic disorder (but not severe enough to be classed as specific psychiatric disorder).
  • Symptoms present for less than 6 months
21
Q

What is acute stress disorder?

A
  • Acute stress reaction that occurs in the first 4 weeks after a person has been exposed to a traumatic event (threatened death, serious injury e.g. road traffic accident, sexual assault etc).
  • This is in contrast to post-traumatic stress disorder (PTSD) which is diagnosed after 4 weeks.
22
Q

What are features of Acute Stress disorders?

A
  • Intrusive thoughts e.g. flashbacks, nightmares
  • Dissociation e.g. ‘being in a daze’, time slowing
  • Negative mood
  • Avoidance
  • Arousal e.g. hypervigilance, sleep disturbance
23
Q

What is the management of Acute Stress Disorder?

A
  • 1st Line: Trauma-focused cognitive-behavioural therapy (CBT)
  • Benzodiazepines
    • sometimes used for acute symptoms e.g. agitation, sleep disturbance
    • should only be used with caution due to addictive potential and concerns that they may be detrimental to adaptation