PT clinical correlate Flashcards
1
Q
PTH causes of hyperCa
Meds
A
Primary hyperPTH (adenoma/hyperplasia/carcinoma) Tertiary hyperPTH (CRF- high phos/VD)
Thiazides, li, calcium antacids (milk-alkali)
2
Q
Thiazides will inc
Lithium inc setpoint of _____, so higher serum ____ needed to stop PTH
A
renal Ca resporption
PTH, Ca
3
Q
PTHrP secreted by solid tumors mimics
Extensive bone lysis assc w
can also cause
A
bone/renal effects of PTH (normal PTH is low)
MM/metastatic breast cancer
hyperCa
4
Q
VD related causes of hyperCa
MCC of hyperCa from VD
Granulomatous dz causes, which results in
Dx FHH
A
granulomatous dz- sarcoid, TB, HL
OTC VD overdose
extra renal conversion of 24OHVD to VD3, PTH
24h urinary Ca (should be low)
5
Q
Steps to narrow Ddx
with high PTH, next step
A
stop meds, run labs (PTH, Ca, VD)
PT scan
