Psychotropics Flashcards
SSRIs function by
inhibiting the reuptake of serotonin
SNRIs increase ___
serotonin and norepinephrine
TCAs inhibit the reuptake of ____ and ___
norepinephrine and serotonin
MAOI act by ___
limiting the metabolism of monoamines such as
dopamine, serotonin and norepinephrine
First line treatments for depression are ____
SSRIs such as fluoxetine, sertraline, and paroxetine
Second line and third line treatments for depression include ___
TCA
atypical antidepressants
Fluvoxamine is a ___
SSRI
Fluoxetine should be given in the _____
am to prevent insomnia
Rasagiline (Azilect) is a ___
MAO inhibitor
Selegiline (Eldepryl, Zelapar) is a ____
MAOI
Isocarboxazid (Marplan) is a ___
MAOI
Phenelzine (Nardil) is a
MAOI
Tranylcypromine (Parnate) is a
MAOI
MAO inhibitors should be discontinued _______ before starting a new antidepressant
two weeks
If switching from another antidepressant to a MAO inhibitor a waiting period of ______ is necessary, except for fluoxetine which requires ___
two weeks
five weeks
avoid foods rich in ____ when on MAO inhibitors such as ______
tyramine
red wine, chocolate, aged cheese, smoked or processed meats, fava beans
can lead to hypertensive crisis
TCA increase the effects of ________, which may result in ____
anticholinergic drugs
dry mouth, urine retention and constipation
amitriptyline hydrochloride is a
TCA
Amoxapine is a
TCA
Clomipramine is a
TCA
Desipramine is a
TCA
Doxepin is a
TCA
Imipramine hydrochloride is a
TCA
Nortriptyline is a
TCA
Depression accompanied by weight loss, anorexia and insomnia is well treated by ___
TCA
First line treatments for anxiety are
SSRIs and SNRIs
Second line treatments for anxiety are
buspirone or imipramine
Third line therapy for anxiety includes
adjunctive therapy with pregabalin or buspirone
Buspirone’s onset of action is
2-4 weeks
Bupropion is a
atypical antidepressant
Trazodone and mirtazapine are
atypical antidepressants
