Psychotropics Flashcards

1
Q

SSRIs function by

A

inhibiting the reuptake of serotonin

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2
Q

SNRIs increase ___

A

serotonin and norepinephrine

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3
Q

TCAs inhibit the reuptake of ____ and ___

A

norepinephrine and serotonin

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4
Q

MAOI act by ___

A

limiting the metabolism of monoamines such as

dopamine, serotonin and norepinephrine

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5
Q

First line treatments for depression are ____

A

SSRIs such as fluoxetine, sertraline, and paroxetine

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6
Q

Second line and third line treatments for depression include ___

A

TCA

atypical antidepressants

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7
Q

Fluvoxamine is a ___

A

SSRI

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8
Q

Fluoxetine should be given in the _____

A

am to prevent insomnia

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9
Q

Rasagiline (Azilect) is a ___

A

MAO inhibitor

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10
Q

Selegiline (Eldepryl, Zelapar) is a ____

A

MAOI

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11
Q

Isocarboxazid (Marplan) is a ___

A

MAOI

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12
Q

Phenelzine (Nardil) is a

A

MAOI

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13
Q

Tranylcypromine (Parnate) is a

A

MAOI

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14
Q

MAO inhibitors should be discontinued _______ before starting a new antidepressant

A

two weeks

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15
Q

If switching from another antidepressant to a MAO inhibitor a waiting period of ______ is necessary, except for fluoxetine which requires ___

A

two weeks

five weeks

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16
Q

avoid foods rich in ____ when on MAO inhibitors such as ______

A

tyramine
red wine, chocolate, aged cheese, smoked or processed meats, fava beans

can lead to hypertensive crisis

17
Q

TCA increase the effects of ________, which may result in ____

A

anticholinergic drugs

dry mouth, urine retention and constipation

18
Q

amitriptyline hydrochloride is a

A

TCA

19
Q

Amoxapine is a

A

TCA

20
Q

Clomipramine is a

A

TCA

21
Q

Desipramine is a

A

TCA

22
Q

Doxepin is a

A

TCA

23
Q

Imipramine hydrochloride is a

A

TCA

24
Q

Nortriptyline is a

A

TCA

25
Q

Depression accompanied by weight loss, anorexia and insomnia is well treated by ___

A

TCA

26
Q

First line treatments for anxiety are

A

SSRIs and SNRIs

27
Q

Second line treatments for anxiety are

A

buspirone or imipramine

28
Q

Third line therapy for anxiety includes

A

adjunctive therapy with pregabalin or buspirone

29
Q

Buspirone’s onset of action is

A

2-4 weeks

30
Q

Bupropion is a

A

atypical antidepressant

31
Q

Trazodone and mirtazapine are

A

atypical antidepressants