Psychosis And Schizophrenia Flashcards

1
Q

How is psychosis defined?

A

A mental state in which reality is greatly distorted which typically presents with delusions, hallucinations, thought disorder

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2
Q

What are some non-organic causes of psychosis?

A

Schizophrenia, schizotypical disorder, schizoaffective disorder, acute psychotic episode, delusional disorder, secondary to mania/depression

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3
Q

What are some organic causes of schizophrenia?

A

Drug induced, iatrogenic, delirium, dementia, endocrine and metabolic disturbances, post-partum psychosis

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4
Q

What is late paraphrenia?

A

Late onset schizophrenia where hallucinations and delusions are prominent but thought disorders and catatonia are rare

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5
Q

When does post-partum psychosis occur?

A

Within the first 2 weeks following birth

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6
Q

What is schizophrenia?

A

A psychotic condition characterised by hallucinations, delusions and thought disorders which lead to functional impairment.
It occurs in the absence of organic disease, alcohol or drug-related disorders and not secondary to elevation or depression of mood

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7
Q

What are some biological risk factors for schizophrenia?

A

Family history, obstetric complications, young age, smoking cannabis or using psychostimulants

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8
Q

What are the positive symptoms seen in schizophrenia? (Delusions Held Firmly Think Psychosis)

A

Delusions, hallucinations, formal thought disorder, thought interference, passivity phenomena

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9
Q

What is a delusion?

A

A fixed false belief which is firmly healed despite evidence to the contrary and goes against their normal social and cultural belief system

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10
Q

What are schneider’s first rank symptoms for schizophrenia?

A

Delusional perception, 3rd person auditory hallucinations, thought interference (withdrawal, insertion, broadcast)

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11
Q

What are the negative symptoms of schizophrenia? (AAAAAA)

A

Avolition, asocial behaviour, anhedonia, alogia, blunted affect, attention defecits

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12
Q

What are the different classifications of schizophrenia according to ICD-10?

A

Paranoid (positive symptoms dominate)- most common
Postschizophrenic depression (depression predominates with schizophrenic episode in last 12 months with some symptoms still present)
Hebephrenic (thought disorganisation predominates)
Catatonic
Simple (negative symptoms without psychotic)
Undifferentiated
Residual

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13
Q

What are poor prognostic factors for schizophrenia?

A

Strong family history, gradual onset, low IQ, premorbid history of social withdrawal, no obvious precipitant

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14
Q

What biological treatment is used for schizophrenia?

A

Antipsychotics- atypical are 1st line, depot considered if poor compliance, clozapine after 2 others havent responded

Adjuvants- lithium and antidepressant can augment antipsychotics, benzodiazepines can be used for short term relief of insomnia, agitation

ECT- for those resistant to pharmacological agents or catatonic schizophrenia

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15
Q

What are psychological therapies used in schizophrenia?

A

CBT- reduces residual symptoms
Family therapy- psychoeducation helps families reduce high levels of expressed emotion which in turn reduces relapse rates
Art therapy- alleviates negative symptoms

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16
Q

What social management can be considered for schizophrenia?

A

Support groups- help facilitate successful rehabilitation back into community
Peer support
Supported employment programmes

17
Q

How would you treat the first episode of schizophrenia?

A

Agree on atypical anti-psychotic with family/support worker
Titration to minimum effective dose and adjust according to response and tolerability