Psychosis

Question 1

What are the side feet a of neuroleptics

Answer 1

EPSEs
Parkinsonism
Akethisia
Tardive dyskinesia
Neuroleptic malignant syndrome

Question 2

What is Neuroleptic malignant syndrome

Answer 2

Neuroleptic malignant syndrome (NMS) is a rare, but life-threatening, idiosyncratic reaction to neuroleptic medications that is characterized by fever, muscular rigidity, altered mental status, and autonomic dysfunction. NMS often occurs shortly after the initiation of neuroleptic treatment, or after dose increases

Question 3

What are the clinical presentation of neuroleptic malignant syndrome

Answer 3

Severe muscular rigidity
Hyperthermia (temperature >38°C)
Autonomic instability
Changes in the level of consciousness

Other Sx: Diaphoresis, Pallor, Dysphagia, Dyspnea, Tremor, Incontinence, Tachycardia, Shuffling gait, Psychomotor

Question 4

Management of neuroleptic malignant syndrome

Answer 4

Discontinue treatment
Supportive treatment=Treat symptoms

Question 5

What are the potential complications of neuroleptic malignant syndrome

Answer 5

Seizures
Cardiovascular arrhythmia
Renal failure
Hepatic failure
Respiratory failure
Aspiration pneumonia
DIC (disseminated intravascular coagulation)
Decompensation of psychiatric disease following withdrawal of neurotics
Pulmonary embolism and DVT