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PSYCH EOR > Psychoses > Flashcards

Psychoses Flashcards

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1
Q

delusional disorder

A

> 1 delusion lasting >1 MO w/o other psychotic symptoms

no significant impairment in function, no better explanation

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2
Q

brief psychotic disorder

A

> 1 psychotic symptoms with onset and remission in less than 1 month

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3
Q

schizophreniform disorder

A

schizophrenia but <6 mo duration

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4
Q

schizoaffective disorder

A

schizophrenia + mood disturbance (MDD or manic)

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5
Q

schizophrenia (general)

A

> 6 mo duration of illness along with functional decline

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6
Q

positive symptoms of schizophrenia

A

excess dopamine receptors

hallucinations or delusions, disorganized speech, thinking, abnormal behavior

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7
Q

sensory perception w.o physical stimuli

A

hallucinations

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8
Q

hallucinations (list) (6)

A
  1. auditory (MC)
  2. visual
  3. olfactory
  4. tactile
  5. somatic
  6. gustatory
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9
Q

fixed belief held with strong conviction despite other evidence

A

delusions

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10
Q

delusion (list) (8)

A
  1. persecutory
  2. reference
  3. control
  4. grandiose
  5. nihilism
    6 erotomania
  6. jealousy
  7. doubles
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11
Q

persecutory delusions

A

person/force interfering with them, observing them or wishing harm

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12
Q

delusions of reference

A

random events take on personal significance (directed at them)

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13
Q

grandiose delusions

A

unrealistic beliefs in one’s powers and abilities

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14
Q

nihilism

A

exaggerated belief in futility of everything/catastrophic events

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15
Q

doubles delusions

A

believes family member or close person replaced by identical double

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16
Q

negative symptoms of schizophrenia

A

dopamine dysfunciton

flat emotional affect, evolution

17
Q

RF of schizophrenia

A

family history***

18
Q

epidemiology of schizophrenia

A

MC in men

show in early 20s for men, late 20s for women

19
Q

management of schizophrenia (general)

A

antispsychotics – 2nd gen preferred

AKA neuroleptics

20
Q

atypical drugs MOA

A

CNS dopamine D4 receptor and serotonin antagonists

21
Q

why would I give a patient clozapine

A

resistance developed to other antipsychotics

22
Q

S/E of atypical antipsychotics

A 
extrapyramidal sxs
increased prolactin 
hyperglycemia 
hyperlipidemia 
weight gain 
NMS
23
Q

CIs of atypical antipsychotics

A

QT prolongation

24
Q

clozapine

A

atypical given if resistance develops

causes agranulocytosis and myocarditis

less incidence of EPS

25
Q

olanzapine cautions

A

marked weight gain and DM

26
Q

what are extrapyramidal symptoms?

A

rigidity
bradykinesia
tremor
akathisia

27
Q

typical/1st gen antipsychotics MOA

A

dopamine antagonists

*decreased dopamine activity causes all SEs

28
Q

typical/1st gen antipsychotics S/es

A 
extrapyramitdal symptoms 
dyskinesia 
parkonsonism 
tardive dyskinesia 
NMS
29
Q

list of 3 EPS symptoms

A
  1. dyskinesia/dystonic reaction
  2. tardive dyskinesia
  3. Parkinsonism
30
Q

dystonic reactions definition and cause

A

reversible EPS, hours to days after initiation of typical neuroleptics

caused by disruption of dopamine/ach balance = excessive AcH

31
Q

symptoms dyskinesia

A 
trismus 
protrusion of tongue 
facial grimacing 
torticollis 
difficulty speaking
32
Q

tx of dyskinesia

A

IV Diphenhydramine

add anticholinergic agent (I.e. Benztropine)

33
Q

tardive dyskinesia

A

repetitive involuntary movements

mostly involving extremities and face

I.e. lip smacking, teeth grinding, rolling of tongue

seen with LONG TERM use

34
Q

life threatening disorder due to D2 inhibitor

A

NMS

35
Q

NMS symptoms

A

mental status changes
extreme muscle rigidity
tremor
autonomic instability (tachycardia, hyperthermia, fever)

36
Q

tx of NMS

A 
d/c offending agent
dopamine agonists (bromocriptine)
37
Q

C/I for haldol

A

Parkinson disease
anticoagulant use
severe cardiac disorder

PSYCH EOR (4 decks)

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