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Psychos Flashcards

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1
Q

How do first generation (Typical) antipsychotics work?

A

D2 antagonists

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2
Q

What are examples of typical antipsychotics?

A

Chlorpromazine

Haloperidol

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3
Q

What are the side effects of typical antipsychotics?

A

Extrapyramidal side effects

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4
Q

What are Extrapyramidal side effects?

A

Tardive dyskinesia
Acute dystonic reaction
Parkinsonism
Akathisia

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5
Q

What is Tardive dyskinesia?

A

Orofacial involuntary movements e.g. Lip smacking

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6
Q

What is an acute dystonic reaction?

A

Oculogyric crisis

Torticollis

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7
Q

What is an oculogyric crisis?

A

Sustained, unwanted upward deviation of the eye

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8
Q

What is torticollis?

A

Painful muscular contraction of the sternocleidomastoid muscle - L side

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9
Q

How is torticollis treated?

A

procyclidine

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10
Q

What is thought attention?

A

Thought insertion

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11
Q

What are the 1st rank symptoms of schizophrenia?

A

Auditory Hallucinations
Thought interference
Passivity
Delusional perception

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12
Q

What types of auditory hallucinations are heard in schizophrenia?

A

hearing thoughts spoken out loud

3rd person hallucinations discussing pt / a running commentary

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13
Q

What is thought interference?

A

Thought insertion, withdrawal, interruption or broadcasting

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14
Q

What is thought broadcasting?

A

The idea that the patients thoughts can be heard / known by those around them

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15
Q

What is Passivity in schizophrenia?

A

feelings, impulses or actions controlled by an external force

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16
Q

What is Loosening of associations?

A

Formal thought disorder

No clear links between successive thoughts

17
Q

What is Flight of ideas?

A

Clear links between successive thoughts despite topic changes

18
Q

What is the management for schizophrenia?

A 
Oral antipsychotic (Typical at first) - Clozapine after 2 failed drugs
CBT to all patients
19
Q

What is BAPD

A

Bipolar affective personality disorder

20
Q

What are the two types of BAPD?

A

Type 1 - Mania + Depressive

Type 2 - Hypomania + Depressive

21
Q

What are the treatments for BAPD?

A 
Mood stabilisers (Lithium / Sodium Valproate)
Dialectical behavioral therapy
22
Q

What are the side effects of Long term lithium use?

A

Hypothyroidism
Irreversible nephrogenic diabetes insipidus
Hyperparathyroidism
Hyperglycaemia

23
Q

How long after first Lithium treatment should the readings be measured?

A

1 week later, 12hrs after dose

24
Q

What tests should be run when on lithium treatment?

A

Lithium levels every 3mo

Thyroid tests every 6mo

25
Q

How can Lithium cause hypercalcaemia?

A

Hyperparathyroidism > Hypercalcaemia

26
Q

What are atypical antipsychotics?

A

2nd generation antipsychotics used after typical ones

27
Q

Why do we use atypical antipsychotics?

A

Due to the impact of EPSEs

28
Q

What are examples of atypical antipsychotics?

A 
Risperidone
Aripiprazole
Clozapine
Quetiapine
Olanzapine
29
Q

What are the worryomg side effects of clozapine?

A

Neutropenic sepsis

Constipation

30
Q

What are the common side effects of olanzapine?

A

Weight gain

31
Q

How do we treat neutropenia in closapine treatment?

A

Lithium!

32
Q

How do we treat weight gain from atypical antipsychotics?

A

Metformin!

33
Q

What are the side effects of sodium valproate?

A

Hair loss
Weight gain
Nausea

Psych (5 decks)

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