Psychophysiological Research Methods Flashcards

1
Q

How does MRI work?

A

MR signals from Hydrogen - appears brighter than other parts

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2
Q

What reduces the MR signal in fMRI?

A

de-oxyHb

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3
Q

What is reverse inference in fMRI?

A

If the activation of a given brain area is associated with a psychological process, then finding activation in that area indicates the presence of the process

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4
Q

What is the logic of reverse inference?

A
  • It reasons backwards
  • One infers the engagment of a cognitive process based on the presence on a brain activation
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5
Q

What are the pros of BOLD fMRI?

A
  • Safest neuroimaging method
  • High spatial resolution
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6
Q

What are the cons of BOLD fMRI?

A
  • Blood flow changes associated with the neuronal activity are slow
  • Scanner space is tight/noisy
  • People with metal in their body can’t ne scanned
  • Inferior to electrophysiological methods e.g. EEG
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7
Q

What is the fundamental limitation of neuroimaging techniques?

A

It is difficult to be certain which activations are necessary for a a given process or task as they co-occur

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8
Q

What is TMS?

A

Transcranial Magnetic Stimulation

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9
Q

How does TMS work?

A
  • A large current is discharged into a coil of wire held on subjects head
  • The current generates a rapidly increasing magnetic field, which passes into brain
  • In the cortex, the magnetic field generates electric currents through neurons’ membranes
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10
Q

What is the effect of TMS?

A
  • Depending on intensity and number of pulses, TMS can increases or decrease excitability
  • In goal directed behaviour, this almost inevitably results in a disrupted pattern of neural activity, impairing performance
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11
Q

What is TMS offered reffered to as?

A

Virtual lesion technique (Similar to a neurological lesion)

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12
Q

What are the challenges of TMS?

A
  • Associated with confounds, hard to control
  • Pulse is associated with a large click, muscle twitches and scal sensations - all have a strong effect on performance
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13
Q

What are the pros of TMS?

A
  • Potential to determine causation and link between brain and behaviour
  • High spatial resolution
  • Excellent temporal resolution, capable of chronometric inference
  • Reversible, allows different conditions to be compared witin the same group
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14
Q

What is the main con of TMS?

A

Limited effects of the brain, can’t stimulate deeper cortical structures

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15
Q

What is an EEG?

A

The change in voltage (electricity) recorded from sensors in the scalp

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16
Q

What are ERPs?

A

Event related potentials - segments of the EEG, time-locked to particular events stimuli

17
Q

How do you visualise ERP data?

A
  • ERP data from a visual Lexical Decision Task - Ps presented with words and non-words and asked to respond with one keypress if the stimulus is a real word
  • Words diverge from non-words at about 250 ms and are clearly different by 400 ms
18
Q

What are the strengths of EEG?

A
  • High temporal resolution
  • Time course of a particluar component in the ERP along with scalp topography can be seen as the spatio-temporal ‘signature’ of certain processes
19
Q

What are the limitations of EEG?

A
  • Limited spatial resolution so it is difficult to pinpoint the exact source of an effect observed on the scalp
20
Q

What is the fovea?

A

Part of the retina with the smallest receptive fields (best acuity) and highest concentration of cone receptors

21
Q

What is there a correspondence between within the eye?

A

Spatial structure of the primary visual cortex and spatial structure of the real world

22
Q

What is cortical magnification?

A

Disproportionately large area of the visual cortex dedicated to the centre of the visual field

23
Q

How are eyes tracked?

A

Most common way relies on monitoring pupil position by emittinf an infrared beam and detecting its reflection from the cornea - reflection is weaker where the pupil is

24
Q

What are the strenghts of eye tracking?

A
  • Safe measurement of position of gaze with very high temporal/spatial resolutionW
25
Q

What are the limitations of eye-tracking?

A

Challenging for individuals who have corrected vision (must wear glasses or contact lenses).