Psychopharmacology for psychiatry Flashcards
What are types of medicine for psychiatry?
-Chemical
-Electrical stimulation
-Structural rearrangements
-Talking (psycho) therapy
What are the different ways of classifying drugs?
-Based on chemical structure
-Based on what illness they treat
-Based on their pharmacology
What are the pros of naming based on chemical structure?
Each chemical has unique structure so is easy to allocate
What are the cons of naming based on chemical structure?
No use in clinical decision making
What are the pros of naming based on the illness they treat?
Easy for doctor to choose a drug after diagnosis
What are the cons of naming based on the illness they treat?
-Many psychiatric medicined work in several disorders
-Most psychiatric disorders have many symptoms and a single medication might not treat them all
2 types of GABA receptors?
GABAa receptor= ion channel
GABAb receptor= g-protein linked receptor
Example of GABAa agonist?
Alprazolam
Example of GABAb agonist?
Baclofen
Examples of enzyme targeting medicines? (blocking enzyme activity)
-Monoamine oxidase inhibitors (MAOIs)= anxiety, depression
-Acetylcholinesterase inhibitors= dementia
-Lithum blocks glycogen synthase kinase for mood stability
Examples of receptor stimulating medicine? (agonist)
-Benzodiazepines enhance GABA= sleep
-Guanfacine enhance noradrenaline= ADHD
Examples of receptor inhibiting medicine? (antagonist)
-Dopamine receptor blockers= schizophrenia
-Serotonin receptor subtype antagonists= depression
-Histamine receptor antagonists= sleep
Examples of neurotransmitter reuptake site blockers?
-Serotonin reuptake inhibitor= depression, anxiety
-Noradrenaline reuptake inhibitor= depression
-Dopamine reuptake inhibitor= ADHD
Example of neurotransmitter reuptake site simulator?
Amfetamine for ADHD
Examples of sodium channel blocking medicines?
-Sodium valproate= epilepsy, mood stabilisation
-Carbamazepine= epilepsy, mood stabilisation
