Psychopharmacology Flashcards
List 5 classifications of antidepressants
Tricyclics Monoamine Oxidase Inhibitors SSRIs SNRI (serotonin/noradrenaline reuptake inhibitors) Novel antidepressants
List 4 side potential side effects of TCAs
Antihistaminic (sedation and weight gain)
Anticholinergic (dry mouth, eyes, constipation)
Antiadrenergic (sedation, sexual dysfunction)
Long QT
What is the function of MAOIs?
Bind irreversibly to monoamine oxidase thereby preventing inactivation of amines such as norepinephrine, dopamine and serotonin leading to increased synaptic levels.
what is the function of SSRIs?
Block the presynaptic serotonin uptake
List 6 SSRIs
Paroxetine Sertraline Fluoxetine Citalopram Escitalopram Fluvoxamine
List 2 SNRIs
Venlafaxine
Duloxetine
List 3 TCAs
Amitriptyline
Nortriptyline
Doxepin
List 2 novel antidepressants
Mirtazapine
Buproprion
List the 3 classes of mood stabiliser
Lithium
Anticonvulsants
Antipsychotics
What is the only medication known to reduce suicide rate?
Lithium (mood stabiliser)
List 3 anticonvulsants
Valproic Acid
Carbamazepine
Lamotrigine
What is the difference between typical and atypical anti-psychotics?
Atypical anti-psychotics have less serious side effects (less extrapyramidal symptoms).
Typical are D2 dopamine receptor antagonists
Atypical are serotonin-dopamine 2 antagonists (SDAs)
How can extrapyramidal side effects caused by anti-psychotics be managed?
Anticholinergics
Dopamine facilitators
Beta-blockers
List some symptoms of atypical anti-
psychotics
Dyslipidaemia
Abnormal LFTs
Elevated Blood Glucose
What is akathisia?
Movement disorder characterized by a feeling of inner restlessness and inability to stay still
