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year 5 misc > psychopharmacology > Flashcards

psychopharmacology Flashcards

1
Q

Antidepressant SE

  • nausea & vommiting
  • appetite / weight change
  • blurred vision
  • anxiety and agitation
  • insomnia, tremor, dizziness
  • headache
  • sweating
A

SSRIs

ex. fluoxetine, sertraline, paroxetine, fluvoxamine, citalopram, Escitalopram

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2
Q

Antidepressant SE

    • nausea & vommiting
  • appetite / weight change
  • blurred vision
  • anxiety and agitation
  • insomnia, tremor, dizziness
  • headache
  • sweating
  • constipation
  • hypertension
  • raised cholesterol
A

SNRIs

ex. venlafaxine, duloxetine

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3
Q

Antidepressant SE

  • sedation
  • increased appetite / weight
  • oedema
A

Noradrenergic and specific serotonin antidepressant

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4
Q

Antidepressant SE

  • tachycardia, arrhythmias
  • dry mouth
  • blurred vision
  • constipation
  • urinary retention
  • postural hypotension
  • sedation
  • nausea, weight gain
A

Tricyclic antidepressants

ex. Amitriptyline, clomipramine, Imipramine,, Lofepramine, Dosulepin

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5
Q

Antidepressant SE

  • Hypertensive crisis (tyramine)
  • postural hypotension, dizziness,
  • drowsiness, insomnia,
  • headache
  • blurred vision
  • nausea and vomiting
  • constipation
A

Monoamine oxidase inhibitors

ex. Phenelzine, tranylcypromine

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6
Q

Antidepressant SE

  • agitation / anxiety
  • nausea
  • sleep disturbance
  • hypertension
A

Reversible inhibitors of monoamine oxidase A

ex. Moclobemide

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7
Q

Trazadone

  • MOA
  • SEs
A
  • 5-HT reuptake blockade and 5-HT2 antagonist

- sedation, dizziness, postural hypotension, tachycardia, causea, constipation, diarrhoea

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8
Q

SSRIs SEs

A
  • nausea & vommiting
  • appetite / weight change
  • blurred vision
  • anxiety and agitation
  • insomnia, tremor, dizziness
  • headache
  • sweating
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9
Q

SSRIs examples

A

fluoxetine, sertraline, paroxetine, fluvoxamine, citalopram, Escitalopram

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10
Q

SNRIs SEs

A
  • nausea & vommiting
  • appetite / weight change
  • blurred vision
  • anxiety and agitation
  • insomnia, tremor, dizziness
  • headache
  • sweating
    PLUS
  • constipation
  • hypertension
  • raised cholesterol
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11
Q

SNRIs examples

A

venlafaxine, duloxetine

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12
Q

NASSAs SEs

A
  • sedation
  • increased appetite / weight
  • oedema
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13
Q

NARI examples

A

reboxetine

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14
Q

TCA SEs

A
  • tachycardia, arrhythmias
  • dry mouth
  • blurred vision
  • constipation
  • urinary retention
  • postural hypotension
  • sedation
  • nausea, weight gain
    prolonged QTc
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15
Q

TCA examples

A

Amitriptyline, clomipramine, Imipramine, Lofepramine, Dosulepin

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16
Q

MAO SEs

A
  • Hypertensive crisis (tyramine)
  • postural hypotension, dizziness,
  • drowsiness, insomnia,
  • headache
  • blurred vision
  • nausea and vomiting
  • constipation
17
Q

MAOi examples

A

Phenelzine, tranylcypromine

18
Q

Reversible inhibitors of MAO

A
  • agitation / anxiety
  • nausea
  • sleep disturbance
  • hypertension
19
Q

SE lithium

A
  • mild tremor
  • GI effects, nausea, vomiting
  • Polyuria, Polydipsia
  • arrhythmia
  • hypothyroidism
  • weight gain
20
Q

Sodium Valproate SEs

A
  • GI effects, nausea, vomiting, diarrhoea
  • liver failure
  • thrombocytopenia
  • hair loss
  • weight gain
21
Q

Carbamazapine SEs

A
  • Rash
  • leucopenia
  • dizziness, ataxia
  • drowsiness, fatigue
  • naursea, vomiting
  • oedema, fluid retention
  • weight gain
  • HYPONATRAEMIA
  • enzyme induction may decrease levels of other drugs eg OCP
22
Q

Lamotrigine SEs

A 
Skin rashes which may be life threatening
hedache, tiredness
Nausea
Dizziness
Insomnia 
Arthralgia and back pain
23
Q

Side effects of antipsychotics (10)

A 
1. Extrapyramidal side effects 
2- Hyperprolactinaemia 
3. Weight gain 
4. Sedation
5. increased risk of diabetes
6. dyslipidaemia 
7. Anticholinergic effect - dry mouth, blurred vision, constipation, urinary retention and tachycardia
8 arrhythmias (prolonged QT) 
9. lower seizure threshold 
10. neuroleptic malignant syndrome
24
Q

treatment of acute dystonia

A

procyclidine

25
Q

treatment of akathesia

A

symptomatic - BB or benzos

change to atypical

26
Q

weight gain particularly SE of which antipsychotics?

A

olanzepine and clozapine

27
Q

clozapine side effect which is particularly worrying?

A

agranulocytosis (not dose dependent)

- stop if WCC <3.0 x 10^9 or neutrophils <1.5x10^9)

28
Q

side effect of clozapine

A

hypersalivation - treated with hyoscine

29
Q

SSRI discontinuation symptoms

A 
increased mood change
restlessness
difficulty sleeping
unsteadiness
sweating
gastrointestinal symptoms: pain, cramping, diarrhoea, vomiting
paraesthesia
30
Q

NARI SEs

A 
dry mouth
constipation
excessive sweating
urinary problems
insomnia
tachycardia
31
Q

NASSA example

A

Mirtazapine

year 5 misc (5 decks)

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