Psychopharmacology

Question 1

What are the effects of THC on the EEG?

Answer 1

Increased frontal alpha and frontal coherence and decreased blood flow to all areas of the brain.

Question 2

What are the effects of LSD on the EEG?

Answer 2

Decreases alpha in a normal EEG, increases fast alpha in slow EEG, and causes little change in a low voltage fast EEG.

Question 3

What are the effects of opioids on the EEG?

Answer 3

Increase in alpha initially, then slowing of alpha and more REM sleep.

Question 4

What are the effects of alcohol on the EEG?

Answer 4

Increases slow waves, especially alpha, and epileptiform discharges with chronic overuse.

Question 5

What are the effects of PCP/angel dust on the EEG?

Answer 5

Increase in slow wave activity and paroxysmal activity with increased dosages.

Question 6

What are the effects of barbituates on the EEG? (anti-anxiety and seizure medication)

Answer 6

Increased rhythmic 18-26Hz activity. More slow activity and less beta with higher dosages.

Question 7

What are the effects of neuroleptics on the EEG? (Used as antipsychotics)

Answer 7

Increased coherence and decreased beta, increases sharp slow theta and decreases alpha blocking with persistent use.

Question 8

Anxiolytics (anti-anxiety)

Answer 8

Decreased alpha and increased beta over 20Hz and decreases paroxysmal activity.

Question 9

Imipramine (tricyclic antidepressant)

Answer 9

Increased slow activity, decreased alpha and increased beta over 20Hz

Question 10

Amitriptyline (tricyclic antidepressant)

Answer 10

Increased slow activity and increased paroxysmal discharges

Question 11

Iproniazid (anti-depressant)

Answer 11

Increase in slow, marked increase in fast wave activity with NO increase in paroxysmal activity

Question 12

MAO inhibitors (class of anti-depressants)

Answer 12

Similiar to stimulants

Question 13

SSRIs

Answer 13

Produce mild frontal and cental beta increase (18-25Hz) and decrease alpha anteriorly

Question 14

Amphetamines (stimulants)

Answer 14

Decreases slow activity and increases 12-26Hz beta and increased alpha activity.

Question 15

Methylphenadate (CNS stimulant)

Answer 15

Decreases delta and theta, increases parietal alpha and 12-15Hz beta.

Question 16

Caffeine and nicotine

Answer 16

Little research on effects, increase in theta during withdrawals that goes away with time

Question 17

Cocaine

Answer 17

Increases frontal alpha during euphoric phase. Well known epileptic potentiator. Increases slow waves with prolonged use (“burns out” dopamine system)

Question 18

Antimanics

Answer 18

Increases theta with mild decrease in alpha. Increases beta activity and is a known epileptiform potentiator

Question 19

Tuburculostatics

Answer 19

Irritant to the CNS and potentiator of paroxysmal activity

Question 20

Methanol (common chemical in products and pharmacuticals)

Answer 20

Acidosis and damage to the optic nerves

Question 21

Mercury

Answer 21

Initially increase fast activity, followed by slow activity and paroxysmal bursts

Question 22

Insecticides

Answer 22

Paroxysmal bursts and EEG slowing

Question 23

Solvents

Answer 23

Dedritic degeneration and demylination

Question 24

Lead

Answer 24

Decrease in IQ, diffused slowing and paroxysmal activity