Psychopharm Flashcards

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1
Q

Common interaction with clozapine

A
Luvox (inh of 1a2)
At johns wort (decreases)
Coffee (augments)
Smoking (inducer 1a2 so decreases)
Grapefruit increases
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2
Q

Phase 2 and Renal/biliary excretion

A

LOT and desvenlafaxine, paliperidone

—-
Li
Gabapentin
Pregabalin
Topamax
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3
Q

SSRIs most on proteins

SSRI least on proteins

A

Sertraline, fluox, parox

—-
Escitalopram

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4
Q

Most NE of antidepressants

A

Paxil

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5
Q

Most serotenergic of antidepressants

A

Cita/eacitalo

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6
Q

SNRI toxicity

A

Hypotension, bowel dysmotility, tachy, diaphoresis, dilated pupils

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7
Q

How do you know it’s a benign lamotrigine rash

A

Spotty, non tender, itchy
Occurs less than 5 days or more than 3 months after starting

Still hold and contact physician

Reduce dose and give antihistamine

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8
Q

Lithium and NSAIDs?
Thiazides?
Spironolactone
Theophylline

A
  • increase
  • increase
  • decrease
  • decrease
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