Psychopharm Flashcards
1
Q
Common interaction with clozapine
A
Luvox (inh of 1a2) At johns wort (decreases) Coffee (augments) Smoking (inducer 1a2 so decreases) Grapefruit increases
2
Q
Phase 2 and Renal/biliary excretion
A
LOT and desvenlafaxine, paliperidone
—- Li Gabapentin Pregabalin Topamax
3
Q
SSRIs most on proteins
SSRI least on proteins
A
Sertraline, fluox, parox
—-
Escitalopram
4
Q
Most NE of antidepressants
A
Paxil
5
Q
Most serotenergic of antidepressants
A
Cita/eacitalo
6
Q
SNRI toxicity
A
Hypotension, bowel dysmotility, tachy, diaphoresis, dilated pupils
7
Q
How do you know it’s a benign lamotrigine rash
A
Spotty, non tender, itchy
Occurs less than 5 days or more than 3 months after starting
Still hold and contact physician
Reduce dose and give antihistamine
8
Q
Lithium and NSAIDs?
Thiazides?
Spironolactone
Theophylline
A
- increase
- increase
- decrease
- decrease