psychopharm Flashcards
What medication causes your skin to fall off?
Lamictal
Information is conducted within the neurons through which of the following methods?
a. chemical neurotransmission
b. electrical neurotransmission
c. protein binding carriers
d. synaptic cleft
b. electrical neurotransmission
Within the neuron, neurotransmission leaves the cell body and travels along which one of the following parts of the neuron?
a. synaptic button
b. cell membrane
c. dendrite
d. axon
d. axon
Which one of the following statements is true?
a. neuron transmission is received only at the synaptic cleft
b. neuron transmission is received at the synaptic cleft, along the axon, and at the cell body
c. presynaptic and postsynaptic neurons must touch for neurotransmission to occur
d. endogenous and exogeneous neurotransmitters use different receptor sites
b. neuron transmission is received at the synaptic cleft, along the axon, and at the cell body
Which one of the following statements is false?
a. the human brain contains over 100 billion neurons
b. there are approximately 100 trillion synapses in the human brain
c. most neurons are present at birth
d. most of the original neurons are lost by age 70
d. most of the original neurons are lost by age 70
Neurotrasmission between neurons occurs by which means?
a. electrical neurotransmission
b. binding to plasma proteins
c. chemical neurotrasmission
d. via the enzymatic transport system
c. chemical neurotrasmission
absorbtion means:
a. the movement of drug from the blood to the rest of the body
b. the alternation of drugs through enzymes in the body
c. the movement of drug from administration site to the blood stream
d. the movement of drug through the hepatic system
c. the movement of drug from administration site to the blood stream
A therapy patient taking an antidepressant for depression announces during his therapy visit that he is going to stop taking the medication and started taking a natural remedy (st johns wort) because he did not like the side effects and he did not want to take synthetic drugs. THe antidepressant medication the client was taking has a long half-life. In addition to instructing him to communicate his plan to his prescribing health care provider, which one of the following is most important to include in patient education at this time?
a. You medication has a long half-life and any new treatment should begin after the drug has cleared your system because you might experience dangerous drug-drug interactions
b. natural remedies also have side effects and if you begin in the natural remedy too soon it will be difficult to tell which drug is causing you distress
c. sometimes it takes about a month or so for your body to adjust to the medication and after that time, the side effects will diminish significantly
d. the problem with natural remedies is that there are no controls to ensure consistent change
a. You medication has a long half-life and any new treatment should begin after the drug has cleared your system because you might experience dangerous drug-drug interactions
Which of the following neurotransmitters are implicated in depression?
a. dopamine
b. serotonin
c. norepinephrine
d. all of the above
e. none of the above
d. all of the above
Dirty drugs refres to:
a. street drugs
b. drugs that are excreted via the feces
c. drugs that resist with several receptors in addition to the intended receptor
d. drugs that have numerous drug-drug interaction
e. drugs that have many side effects
f. a and d
g. c andd e
h. c and e
g. c and e
Which of the following statements is false concerning SSRI’s?
a. they are effective for a braod range of depressions
b. many of them cause weight gain
d. the client must avoid foods containing tyramine
e. they are often the first line of treatment for depression
d. the client must avoid foods containing tyramine
thats MAOIs
Neurotrasmitters are destroyed via:
a. enzymes
b. receptors
c. transporters
d. neurotranmitters are not destroyed
a. enzymes
Clients may be noncompliant with taking a drug like depakote because of the need for frequent blood draws. The purpose of this intervention is to
a. monitor liver function for signs of impairment
b. check blood levels of the drug because fo the narrow therapeutic window
c. check on weight gain
d. a and c
a. monitor liver function for signs of impairment
Which one of the following choices most accurately describes the effect of drug metabolites on therapeutic treatment?
a. active metabolites may potentiate the effect of a drug
b. metabolites are always inactive by products of drug metabolites
c. metabolites are harmless and need not be considered when evaluating the clinical efficacy of drugs
d. non of the above
a. active metabolites may potentiate the effect of a drug
When trying to minimize side effects and treatment complications, which one of the following would be the best selection rank (least to greatest side effects) for the pharmacological management of depression?
a. MAOI’s, SSRIs, Tricyclics
b. SSRIs, MAOI’s, Tricyclics
c. Tricyclics, SSRIs, and MAOIs
d. SSRIs, Tricyclics, MAOIs
d. SSRIs, Tricyclics, MAOIs
What class of drugs is most commonly used to treat bipolar illness?
a. antidepressants
b. bensodiazepines
c. antipsychotics
d. anticonvulsants
d. anticonvulsants
When being treated with lithium it is important to check blood levels because
a. of it teratogenic effects
b. of its narrow therapeutic window
c. it helps to monitor side effects
d. it helps to monitor weight gain
b. of its narrow therapeutic window
Stevens Johnson Syndrome is a life threatening side effect of some medications. It is characterized by:
a. nausea and vomiting
b. memory loss
c. rash followed by sloughing of the skin
d. liver failure
c. rash followed by sloughing of the skin
What drug is most associated with mothers little helper?
a. diazepam
b. prozac
c. pamelor
d. escitalopram
a. diazepam
Which of the following statements concerning MAOIs is true?
a. there are used to treat atypical depression
b. the client must avoid foods containing tyramine
d. they habe only a few mild side effects
e. b and c
f. a and b
g. none of the above
f. a and b
Knowledge about the half-life of a drug is important because
a. it helps determine the appropriate dosage
b. it helps determine when a new drug can be started following discontinuation of a previous drug
c. it informs the clinician how the client is responding
d. a and b
d. a and b
The monoamine hypothesis of depression suggests taht depression is predominantly caused by a deficiency of serotonin
False
Many psychotropic medications are bound extensively to serum proteins, usually albumin
True
The cytochrome P450 system is involved in drug metabolism in the kidneys
False
Half-life is the amount of time required for the serum concentration of a drug to be reduced by 50%
True
A bound drug is inactive, an unbound drug in active
True
Bioequivalence is guaranteed by the FDA for all generic drugs
False
Prescriptive authority is granted in some states and Guam
True
Sexual dysfunction is a common side effect among the SSRIs
True
Pharmocokinetics refers to the body’s effect on a drug
True
Duloxetine and venlafaxine are considered SNRIs
True
alprazolam
benzo
divalproex
anticonvulsant
Zoloft
SSRI
imipramine
tricyclic antidepressant
oxcarbazepine
anticonvulsant
Strattera
SNRI
fluoxetine
SSRI
nortriptyline
tricyclic antidepressant