Psychopathology: Disruptive, Impulsive, Conduct Disorders, Substance related, Neurocognitive and Personality Disorders Flashcards

1
Q

What are substance use disorders?

A

“a cluster of cognitive, behavioral, and physiological symptoms indicating that the individual continues using the substance despite significant substance-related problems”

  • can be diagnosed for all classes of substances except caffeine
  • severity is determined by number of symptoms
  • specifier based on early or sustained remission, maintenance therapy, controlled environment
  • 2 or more characteristic symptoms within a 12 month period
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2
Q

What are substance-induced disorders?

A
  • substance intoxication
  • substance withdrawal
  • substance/medication-induced mental disorder (e.g. substance-induced depressive disorder, anxiety disorder, major neurocognitive disorder, withdrawal delirium)
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3
Q

What are some of the alcohol induced disorders? (alcohol intoxication, alcohol withdrawal, alcohol-induced major neurocognitive disorder)

A

alcohol intoxication: problematic behavioral and psychological changes (e.g. inappropraite sexual or aggressive behavior, mood lability, impaired judgement) with at least 1 of 6 symptoms: slurred speech, incoordination, unsteady gait, nystagmus, impaired attention or memory, stupor, coma

alcohol withdrawal: at least 2 of 8 symptoms that develop within several hours to a few days following cessation or reduction of heavy and prolonged alcohol use - (1) autonomic hyperactivity, (2) hand tremor, (3) insomnia, (4) nausea or vomiting, (5) transient hallucinations or illusions, (6) anxiety, (7) psychomotor agitation, (8) generalized tonic-clonic seizures

alcohol-induced major neurocognitive disorder: significant decline in 1 or more cognitive domains that interferes with everyday activities. Specifier: nonamnestic-confabulatory type or amnestic-confabulatory type (Korsakoff syndrome – thiamine deficiency, anterograde and retrograde amnesia, confabulation)

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4
Q

What does opioid intoxication and opioid withdrawal look like?

A
  • Opioid Intoxication: initial euphoria followed by apathy or dysphoria and impaired judgement + pupillary constriction and at least 1 of 3 symptoms during or after opioid use – drowsiness or coma, slurred speech, impaired attention or memory. (can include or not perceptual disturbances - i.e. hallucination with intact reality testing or illusions in the absence of delirium)
  • Opioid withdrawal: 3 of 9 symptoms – dysphoric mood, nausea or vomiting, muscle aches, diarrhea, yawning, fever, insomnia

Opioids = opium, heroin, morphine, codeine (which are derived from opium poppy, synthetic and partly-synthetic drugs - methadone, oxycodone, hydrocodone, fentanyl)

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5
Q

What does stimulant intoxication and withdrawal look like?

A

stimulant intoxication: maladaptive behavioral and psychological changes (e.g. euphoria or affective blunting, hyper-vigilance, interpersonal sensitivity, anxiety or anger, impaired judgement) and 2 of 9 symptoms – tachycardia or bradycardia, pupillary dilation, elevated or lowered blood pressure, perspiration or chills, nausea or vomiting, weight loss, psychomotor agitation or retardation, respiratory depression or cardiac arrhythmia, seizures or coma

stimulant withdrawal: dysphoric mood + at least 2 of 5 physiological changes develop within a few hours to several days after cessation or prolonged stimulant use – fatigue, vivid and unpleasant dreams, insomnia or hypersomnia, increased appetite, psychomotor agitation or retardation

Stimulants – amphetamines, methamphetamines, cocaine

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6
Q

What does tobacco withdrawal look like?

A

4 of 7 symptoms that develop within 24 hours of abrupt cessation or reduction of the use of tobacco:

1 - irritability
2 - anger or anxiety
3 - impaired concentration
4 - increased appetite
5 - restlessness
6 - depressed mood
7 - insomnia

duration and severity of withdrawal symptoms - peak 48-72 hours following cessation of nicotine use and gradually wane over several weeks

craving for nicotine last longer than withdrawal and can be cause of early and late relapse

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7
Q

What is hallucinogen persisting perception disorder?

A

re-experiencing at least one of the perceptual symptoms that were experienced while intoxicated with LSD or other hallucinogen

visual disturbances: flashes of color, halos around objects are most common

episodes/flashbacks: very brief but may recur over days, weeks, months or longer

reality testing during episodes is intact (i.e. the person is aware that current symptoms are due to previous drug use)

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8
Q

General components to treatment of substance-related disorders?

A
  • usually includes individual, family and/or group interventions and medication
  • cognitive behavioral therapy, motivational interviewing, contingency management, family behavior therapy, community reinforcement approach, personalized normative feedback, text messages, relapse prevention therapy, 12-step facilitation
  • combined interventions most effective (e.g. tobacco use disorder - therapy (critical thinking skills training and social support) and medication - nicotine nasal spray & varenicline: both are effective alone, more effective together)
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9
Q

What is the community reinforcement approach (CRA) to substance use treatment?

A

Based on principles of operant conditioning and “helps people arrange their lifestyles so that healthy, drugfree living becomes rewarding and thereby competes with alcohol and drug use”

  • Community Reinforcement and Family Training (CRAFT) - for individuals who refuse treatment. Works with Concerned Significant Other (CSO). Primary Goals:
    (a) help CSO influence user to enter treatment
    (b) teach CSO procedures to help reduce user’s use
    (c) help CSO make positive life changes that improve CSO’s quality of life whether or not user gets treatment
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10
Q

What is the voucher-based reinforcement therapy (VBRT) to substance use treatment?

A

Contingency management: patients get vouchers to use for goods and services when they reach treatment goals (e.g. neg drug screens)

Effective as a standalone treatment (for cocaine, opiates, marijuana, tobacco)

VRBT can be better when combined - best for promoting abstinence at first, CBT less useful at the beginning better for maintaining abstinence and developing coping skills

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11
Q

What is the personalized normative feedback (PNF) to substance use treatment?

A

Based on the assumption that “if perceptions of the prevalence of a given behavior influence one’s own behavior…and one overestimates the prevalence of that behavior, then correcting the misperception should reduce the behavior”

  • provide users with information that allows them to compare actual frequency and perceived frequency for a typical person in their peer group with the actual average

(originally developed as a brief stand alone intervention for heavy drinking college students who tend to overestimate the amount/frequency of their peers and the misperception was associated to higher levels of drinking. also applicable to gambling, eating disorders, IPV and other problematic behaviors. Can be combined with motivational interviewing)

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12
Q

What is the text-messages approach to substance use treatment?

A

Serve four major functions:
appointment and medication reminders, health care information, support, means of self monitoring

text message smoking cessation alone higher quit rates than minimal smoking cessation support from a doctor.

similar quit rates between text alone quit rate and other stand alone interventions

higher quit rates combining text with other interventions

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13
Q

What is the relapse prevention therapy (RPT) for substance use treatment?

A

CBT approach to relapse prevention - substance addiction as a “learned habit pattern” and lapses are typically precipitated by a high-risk situation (e.g. negative emotional state, interpersonal conflict, social pressure)

Lapses likely turn into major relapse with poor coping skills, low self-efficacy, high expectations about the positive side effects of substance and responds to lapse with “abstinence violation effect” (neg emotions, guilt, sense of personal failure)

RPT uses cognitive and behavioral strategies that enable clients to recognize and deal more effectively with high risk situations. (training in coping skills, enhancing self-efficacy, challenging myths about positive outcomes, cognitive restructuring to view lapses as mistakes rather than a personal failure, altering lifestyle factors that increase exposure or reduce resistance to high-risk situations)

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14
Q

What is the Project MATCH approach to substance use treatment?

A

Project MATCH, a multisite clinical trial, compared the effectiveness of cognitive behavioral coping skills therapy, motivational enhancement therapy, and twelve-step facilitation for clients who had received a DSM-III-R diagnosis of alcohol dependence or abuse.

It also evaluated the client-treatment matching hypothesis, which predicts that client outcomes can be improved by matching clients with certain characteristics to treatments most appropriate for those characteristics.

Clients were randomly assigned to one of the three treatments, and clients in each group were categorized in terms of several characteristics (e.g., alcohol involvement, psychiatric severity, anger, and social support for drinking versus abstinence).

Results indicated that, at one-year and three-year follow-ups, all three treatments had produced significant reductions in drinking, with twelve-step facilitation having a slight advantage over the other two treatments.

The results also provided some support for the matching hypothesis. For example, at the three-year follow-up, clients whose social networks were supportive of drinking benefited most from twelve-step facilitation, while clients who were high in anger benefited most from motivational enhancement therapy (Project MATCH Research Group, 1997, 1998).

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15
Q

What is the general description of disruptive, impulse-control, and conduct disorders?

A

problems in the self-control of emotions and behaviors

includes: oppositional defiant disorder, conduct disorder, intermittent explosive disorder

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16
Q

What is diagnostic criteria for oppositional defiant disorder (ODD)?

A
  • for at least 6 months angry/irritable mood, argumentative/defiant behavior and/or vindictiveness that manifest through 4 or more symptoms with at least one person who isn’t a sibling:
  • often loses temper
  • angry and resentful
  • often deliberately annoys others
  • often blames others for their misbehavior/mistakes

in young children: more common in boys
in older kids: about equal between genders
about 30% of children with ODD (especially those with an early onset) also receive a conduct diagnosis)

17
Q

Treatment options for ODD?

A
  • multimodal and tailored to age, symptoms and comorbidities

Psychosocial interventions are first-line and same as conduct disorder treatments

18
Q

Diagnostic criteria of conduct disorders?

A

For the past 12 months has at least 3 symptoms, and at least 1 symptom in past 6 months

persistent pattern of behavior that violate basic rights of others and social norms or rules from the following symptoms:
4 categories – (1) aggression to people and animals, (2) destruction of property, (3) deceitfulness or theft, (4) serious violations of rules

  • people older than 18 and meet criteria for antisocial personality disorder can’t be diagnosed with conduct disorder
  • most often in boys, mostly emerges in middle childhood and adolescence

3 subtypes:
(1) childhood onset - for those with at least one symptom before 10 - more associated to aggressiveness and greater risk of antisocial and/or substance disorder
(2) adolescent onset for those with no symptoms before 10 - more likely to remit in adulthood
(3) unspecified onset

  • severity based on number of conduct problems and consequences (mild, moderate, severe)
19
Q

What are the possible etiology sources (five) of conduct disorder?

A
  • Heredity
  • Brain abnormalities in structure and functioning
  • Neurotransmitter and neuroendocrine abnormalities
  • Prenatal exposure to opiates, alcohol
  • Negative parenting practices (harsh and inconsistent punishment
20
Q

What neurotransmitters are connected to the etiology of Conduct Disorder (CD)?

A
  • reduced serotonin and dopamine contribute to increased aggression and reduced sensitivity to punishment, increased risk-taking behaviors
  • baseline cortisol levels were similar between adolescents with and without CD in the morning, differed significantly in the evening
  • adolescents with CD didn’t experience the typical increase in cortisol and cardiovascular response to stressful even though they have a similar negative affect to those without CD (poorer coordination between emotional and physiologic arousal)
21
Q

What are the two types of antisocial behavior profiles (by Moffitt) that align with the DSM profile of Conduct Disorder (childhood and adolescent type)?

A

1: life-course-persistent type - pattern of increasingly serious antisocial behaviors that begin in early childhood - due to a combination of neuropsychological deficits that affect temperament, cognitive abilities and others plus adverse child-rearing environment

2: adolescence-limited type - temporary and situational type of antisocial behavior that’s due to a “maturity gap” between biological and sexual maturity and their social maturity - antisocial behavior is a way to attain mature status

22
Q

What is the first line of treatment for Conduct Disorder and what are the four main categories?

A

Psychosocial interventions

1 - child focused interventions
2 - parent focused interventions
3 - family focused interventions
4 - multimodal

23
Q

What are the child focused interventions for conduct disorder and other disruptive behaviors?

A

Problem solving skills training - focuses on cognitive processes that underlie problematic behavior and helps them:

  • perceive the feelings of others
  • understand the consequences
  • identify prosocial ways to resolve interpersonal problems and conflicts
24
Q

What are the parent focused interventions for conduct disorder and other disruptive behaviors? (3 types)

A

(1) PMTO Oregon (2) Kazdin PMT (3) PCIT

1 - Parent management training Oregon model (PMTO) - for parents with kids 2- 18 years old

Based on assumption that children’s aggressive, antisocial and other externalizing behaviors are result of escalating cycle of coercive interactions between parents and children

Helps parents replace coercive parenting practices with positive parenting (includes positive reinforcement, non-coercive discipline, setting limits, monitoring child’s behaviors)

2 - Kazdin’s parent management training (PMT) for parents with kids 2 to 17 years old

Based on principles of operant conditioning - replaces antecedents and consequences that maintain problematic behaviors with antecedents and consequences that foster desirable behaviors (positive effects on child symptoms, parent symptoms, relationships - PMT and PSST is even more effective)

3 - PCIT for parents with kids 2-7 years old with severe problems and are at risk of experiencing maltreatment - alters negative parent-child interactions - includes child-directed interaction and a parent-directed interaction (effective disciplinary practices)

25
Q

What are the family focused interventions for conduct disorder and other disruptive behaviors? (two types)

A

(1) Functional Family Therapy FFT
(2) Multidimensional family therapy MDFT

1: FFT - for families with child 11 - 18 y/o
Based on assumption that problematic behaviors within a family help regulate relational connections by fostering interdependence or independence and regulate relational hierarchies by creating power structures - primary goal is to replace problematic behaviors with non-problematic behaviors that serve same function

2: MDFT - for families with child 11 - 21 y/o substance use comorbid internalizing and externalizing and/or delinquency - incorporates elements of family systems, ecological theory, developmental psychology - primary goal to reduce or eliminate substance use, aggression and other symptoms - improve adolescent and family functioning by targeting: (1) adolescent (2) parents (3) family interactions (4) extrafamilial sources of influence

26
Q

What are the multimodal interventions for conduct disorder and other disruptive behaviors?

A

(1) Multisystemic therapy (MST): intensive family and community-based intervention for 12-18 y/o who are at imminent risk for out-of-home placement
* based on Bronfenbrenner’s ecological theory - assumes problematic behavior are result of multiple risk factors from all levels and interventions are needed at all levels (effective for families of all backgrounds) (MST-CAN is for abused children 6-17 years old)

(2) Multidimensional treatment foster care (MFTC) - alternative to residential care for children and adolescents - developing behavioral management plan that is tailored to child and administered by treatment team (home, school, community) - children live with highly trained and supervised foster parents while biological parents receive training and support for reunification

27
Q

What are the multimodal interventions for conduct disorder and other disruptive behaviors that have harmful effects?

A
  • Scared Straight (used for prevention or intervention) of conduct disorder: increases likelihood that juvenile offenders and at-risk juveniles will engage in criminal behaviors in the future
  • Confrontational “rap sessions” and nonconfrontational (educational) approaches have similar negative effects - worse outcomes for seriously delinquent youth
28
Q

What is intermittent explosive disorder?

A

Outbursts due to a failure to control aggressive impulses as manifested by one of the following:

(a) verbal or physical aggression that occurs on average, twice weekly for at least 3 months

(b) 3 behavioral outbursts in a 12 month period that resulted in damage or destruction of property and/or physical injury to other people or animals

Level of aggression must not be proportional to provocation or any precipitating social stressor - outbursts must not be pre-mediated or committed to achieve a tangible outcome

Must be at least 6 years or equivalent developmental level
Onset is usually childhood or adolescence

29
Q

What are the criteria for delirium?

A

(a) disturbance in attention and awareness that develops over a short period of time (often hours to a few days) - represents a change from baseline attention and awareness, and tends to fluctuate