Psychomotor Stimulants

Question 0

What are the following neurotransmitters known as? {E, NE, DA, 5-HT}

Answer 0

Biogenic amines

Question 1

Name the four neurotransmitters stimulated by psychomotor stimulants.

Answer 1

1. Epinephrine
2. Norepinephrine
3. Dopamine
4. Serotonin

Question 2

Term used for psychomotor stimulants because they stimulate sympathetic synapses and mimic sympathetic arousal.

Answer 2

Sympathomimetic

Question 3

Name the three synthetic psychomotor stimulants.

Answer 3

1. Amphetamine
2. Methamphetamine
3. Methylphenidate

Question 4

Name the three naturally occurring substances derived from plant material.

Answer 4

1. Ephedrine
2. Cocaine
3. Cathinone

Question 5

Process that separates cocaine molecule from HCL.

Answer 5

Freebasing

Question 6

Cocaine and HCL mixed with sodium bicarbonate.

Answer 6

Crack

Question 7

True or false: psychomotor stimulants cross the BBB.

Answer 7

True, I.V administration of amphetamine results in brain penetration within seconds.

Question 8

Smoking cocaine is referred to as _________.

Answer 8

Tooting

Question 9

Psychomotor stimulants are concentrated in the _______, _______ and _______.

Answer 9

Spleen, kidneys and brain

Question 10

Amphetamines are excreted in _______ and _______.

Answer 10

Sweat and saliva

Question 11

The half-life of amphetamine is between ___ and ___ hours.

Answer 11

16-34

Question 12

True or false: cocaine is excreted much faster than amphetamine

Answer 12

True

Question 13

The half-life of cathinone is ______.

Answer 13

90 minutes

Question 14

The half-life of cocaine is ______.

Answer 14

40 minutes

Question 15

The experience of extreme exhaustion, depression, lethargy and hunger following the cessation of moderate to heavy amphetamine exposure.

Answer 15

Crash

Question 16

Minor modifications in the amphetamine molecule yields a slightly more potent methamphetamine called _________.

Answer 16

Methadrine

Question 17

A form of methamphetamine that can be inhaled by smoking.

Answer 17

Hydrochloride

Question 18

A synthesized compound with similar molecule structure to amphetamine.

Answer 18

Methylphenidate (Ritalin)

Question 19

Well tolerated FDA approved drug used for the treatment of narcolepsy with only adverse side effects being headache.

Answer 19

Modafinil

Question 20

True or False: cocaine is a reuptake blocker only.

Answer 20

True, cocaine blocks reuptake

Question 21

True or False: the 3 fold effect on monoamine synapses cause neurotransmitters to leak from vesicles into synaptic cleft

Answer 21

True

Question 22

True or false: 3 fold effect increases the amount of neurotransmitter released in response to action potential

Answer 22

False, it DECREASES the amount of neurotransmitter released

Question 23

Man who used cocaine as a local anesthetic in the eye.

Answer 23

Karl Koller

Question 24

Treatment of narcotic dependence

Answer 24

Buprenorphine

Question 25

Immediate extreme allergic reaction to psychomotor stimulant

Answer 25

Anaphylactic shock

Question 26

These receptors are more enkephalin selective and induce spinal analgesia

Answer 26

Delta receptors

Question 27

These receptors have a high affinity for dynorphin and may mediate spinal analgesia and sedation

Answer 27

Kappa receptors