Psychology Biological Level Flashcards
What was the Avery et al study? (2001)
• SAD
Randomly assigned 95 SAD patients to one of 3 groups
1) Dawn stimulation (began 4:30am)
2) Traditional bright light therapy
3) Placebo of dim red light at dawn
Structured interview -depression rating
Found: (3) showed less improvement & more side effects & complained of insomnia significantly more than others after 4 weeks
Conclusion: SAD symptoms were related to a shift in sleep patterns
Treatments in (1) & (2) helped realign sleep patterns by encouraging inhibition of melatonin at right time - therapeutic & less side effects
Body temperature in SAD ..?
Body temperature tends to rise and fall more in SAD than normal people who are synchronised with their sleep/wake cycle
=> melatonin involved
Reserpine in depression?
Reserpine is a drug used to treat high blood pressure but also reduces seratonin as a side effect and can lead to depression
What was the Mark A Mintum et Al study?
Compared PET scans of 46 depressed brains to 29 non-depressed
Used chemical altabserin which bind to seratonin receptors compared numbers of seratonin receptors
Found: depressed brains had significantly less receptors in hippocampus
Means seratonin levels are limited => depression
Bonson et al (1996) - seratonin & depression
Used questionnaires
Found LSD users who enjoyed hallucinogenic effects BUT also had depression & were being treated with antidepressants tended to have reduced symptoms but normal LSD doses no longer had the same effect
Dopamine and Parkinson’s Disease
Dopamine affects the way the brain controls movement and controls the flow of information to the frontal lobe which is why low levels lead to a decline in cognitive functions like memory, attention, problem solving & can lead to development of Parkingson’s
L-dope drug & dopamine
L-dopa is a drug designed to relieve symptoms of Parkingson’s Disease by raising dopamine levels
Over-medicated patients developed positive symptoms like hallucinations and delusions
What is the dopamine hypothesis
That the brains of schizophrenic patients produce more dopamine than normal brains which causes thee symptoms - overactive dopamine receptors
• amphetamines can cause psychotic like episodes (only positive symptoms) and traditional antipsychotic drugs block dopamine receptors
Robert Plomin (1998) genes & intelligence
Studied 50 students with an IQ score of over 160 and compared their DNA to that of normal/average children
He found a variant of the IGF2R gene on chromosome 6 was twice as common in high IQ than average IQ children
- but small effect of only 4 IQ points intelligence is polygenic
Bouchard and McGue (1981) - genes & intelligence
If HZ twins reared apart have a higher concordance in IQ scores than DZ, then genetics are important in determining intelligence
They found DZ twins reared together had a concordance rate of 60% whereas HZ twins reared apart had a concordance rate of 72%
Cornet et al (1998) genes & intelligence
Studied ‘super bright’ kids with IQ over 136
Found that 33% had IGF2R gene while only 27% of ‘normal’ people have it
But admits that it only accounts for 2% of intelligence
Environmental factors must play a role
Bailey and Pillard (1991) genes and homosexuality
Studied how often both twins were homosexual
Found that DZ twins had a concordance rate is 22% while MZ had a rate of 52%
Strong genetic correlation but other factors but be used to explain why this is not 100%
Kanwisher et al (2012)
• Localisation of function
Aimed to investigate the functions of specific areas of Broca’s area in the brain
Scanned participants using functional magnetic resonance imaging (fMRI) as they performed tasks
• asked to read either meaningful sentences or sequences of nonwords
= A subsection lit up more when processing meaningful sentences
• performed easy and difficult versions of general cognitive tasks e.g. maths are holding a set of locations in memory
= parts of Broca’s Area lit up during the more difficult versions
Found there are two distinct regions in Broca’s area - language and (difficult) general
General region seem to be connected to a larger network across the frontal and parietal lobes and all communicate with each other
Language section also part of a larger language network across - left hemisphere
Conclusion: Broca’s area doesn’t perform one single function i.e. language
Criticism of Kanwisher study?
Peter Hagoot: only tested language and general cognitive => it is unclear if Broca’s area is involved in other areas of cognitive function
What is a life event?
A significant change in a person’s life that disrupts daily routines