Psychoactive Drugs Flashcards
Which of the following are not characteristics of depressants? A Decrease CNS functions B. Raise processing speed C. Cause dizziness D. Lack of coordination
B. Depressants do not generally increase processing speed as they are lower the functions of the brain. Everything else is correct.
How are barbiturates and benzodiazepines similar? How are they different?
Barbiturates/tranquilizers and benzodiazepines are both depressants that function in suppressing the functions of the central nervous system. Both are prescribed to relax a patient or induce sleep, however, barbiturates are no longer used due to the high addiction potential. Barbiturates can also be used as general anesthesia or be used as an anticonvulsant (prevent or reduce the severity of epileptic fits or other convulsions) Benzos are more commonly prescribed as to treat insomnia, anxiety and seizures
Alcohol falls under the psychoactive drug class: depressants. What about alcohol makes it a little odd and doesn’t quite fit the class?
Alcohol has the ability to lower inhibitions, therefore allowing indv to commit to actions that would not normally do, therefore more likely to act on impulses and leads to impaired judgement and reduced self-awareness and self control
Name all drugs that fall under the class of stimulants.
Caffeine - Amphetamines, ex: Adderall Methamphetamines MDMA/ecstasy/mollie Cocaine Nicotine
Along with increased CNS functions, what consequences can come out of stimulants?
Along with the increased HR And BP, stimulants can increase alertness leading to an energetic feeling. However, it can cause jitteriness and even nervousness.
What about nicotine makes it an oddball in the class of stimulants?
Nicotine can cause relaxation, but it can also make a person more alert. [sounds contradicting, but no!]
After a long night out, you and Juan are sitting at a diner and realize that he has an interview in an hour. Still heavily drunk, he insists on sobering up with coffee. What should you tell him?
He should reschedule his interview. Alcohol and coffee does have polar opposite effects, however, they do not cancel one another out as they do not mechanistically function in the same way. Therefore he will simply be a more drunk person.
Besides having the ability to create hallucinations, what other properties does hallucinogens also have? Which other class of psychoactive drugs have the additional characteristics?
Hallucinogens also have the ability to excite or calm the indv as well mirroring stimulants or depressants respectively
Hallucinogens also create a sense of connectedness and can induce intense mood swings in a person.
What is the experience of hallucinogens dependent on?
The exact experiences perceived by an indv, maybe different for another indv because a lot of hallucinogens and their effect are based on indv personalities, where they are, and who they are with.
Opiates/opioids are known for their pain relief. However, what other characteristics can they have to cause them to be potentially classified as another class?
Opiates can depress the CNS as well leading to a decrease in HR and BP. This is why some drugs under this class are in fact classified as depressants instead. HOWEVER!! The mechanism of action is different. Opiates/opioids bind to endorphin receptors while depressants bind to GABA receptors
Which of the following drugs are not opiates? A. Codeine B. Oxycodone C. Barbiturates D. Vicodin
C. Barbiturates. These drugs are a part of depressants and represent the classic definitions of depressants: depress the CNS by decreasing HR, BP, and RR through binding of GABA receptors. [remember, opiatea/opiods also act like depressants as well]
You find a new drug used recreationally among the projects. What properties must this drug contain in order to be classified as an opioid?
It has to be synthetically made to be termed opioids [note: opiates are naturally occurring, though there are used interchangeably; Mneumonic: “at” - n”at”ural - opi”at”es] This new drug has to also depress the central nervous system (therefore decrease HR and BP) and also bind endorphin receptors to create an analgesic effect.
Though psychoactive drugs can be classified based on many things, what are the most common classifications?
There are many drug classifications that can be denoted, therefore not all a single drug can fit nicely into one category as it may share many similar characteristics of different groups. But the most common classifications are:
Legal system
Likelihood of abuse
Biological effect of drugs (classic classification in psych)
What psychoactive classifications (biological effect) does marijuana fall under?
None of the commonly listed ones as it shares characteristics of different ones. Marijuana can cause hallucinations but also it can decrease central nervous systems to cause relaxation.
Alcohol is known to be a disrupter of sleep. Explain why.
Alcohol causes disturbances of REM sleep. This in turn can lead to lack of REM sleep overall and play a role in inhibiting you ability to form memories and new synapses
What negative consequence does both depressants: barbiturate and alcohol share together?
Both can potentially reduce memory, judgement and concentration. Both do have the ability to reduce anxiety (barbiturates induce sleep while alcohol reduces your inhibitions)
As you assess a new benzodiazepine on the market, you are attempting to recall the mechanism of benzos in the body. What happens once the drug has bound onto its receptor?
Benzo binds to GABA receptors of neurons, leading to activated chloride channels in neurons to open. This leads to more chloride entering the neurons creating a negative membrane. This low membrane potential leads to the neurons resilience in excitation, hence why they are good rxs for sleep or anxiety.
What kind of psychoactive drugs are prescribed for insomnia A Stimulants, Oxycodone B. Depressants, Barbiturates C. Depressants, Benzodiazepines D. Depressants, Alcohol
C. Depressants, Benzodiazepines - Short and intermediate acting benzos are prescribed for insomnia only. Long acting benzodiazepines are Rx for anxiety as it has a longer effect. Historically, tranquilizers/barbiturates were Rx for all of these disorders, however, this class of drugs had very addictive potential, leading to the discontinue and occasional use of it only now
In terms of prescription, what is one diagnosis that both stimulants and depressants can be prescribed to an individual?
Anxiety. Molly/Ecstasy and long acting barbiturates can be Rx to an indv to treat their anxiety
What are endorphins and what mimics these?
Endorphins are the body’s natural pain reducing neurotransmitters. Opiates mimic these neurotransmitters leading to a decreased in perception of pain
What about opiates leads to this class of psychoactive drug to have addictive potentials?
With high doses of opiates, indv will have a sense of euphoria leading to recreational uses
Nicotine and caffeine are both physiologically addictive chemicals. What do they both share in terms of withdrawal symptoms?
Without the substances in the body, users can experience irritability, distractibility, and mood changes (depression for caffeine users and anxiety with nicotine users) They do differ in some symptoms such as caffeine users tend to experience headaches which nicotine users tend to experience insomnia.
How does the neurochemical mechanism of cocaine differ from amphetamine?
Cocaine causes the release of dopamine, serotonin and norepinephrine which amphetamine (and methamphetamine) causes the release of dopamine only. All 3 causes a sense of euphoria
What do most recreational stimulants share in common during the crash stages of substance use?
Cocaine, methamphetamine, and amphetamine all depletes their respective neurotransmitters. Once the effect wears off, the crash is experience, where emotional disturbances (such as irritability and depression) and convulsions/seizures can be experienced by users