Psychoactive Drugs

Question 1

Categories of psychoactive drugs (4)

Answer 1

Cannabis - THC
Depressants
Stimulants
Hallucinogens

Question 2

Major processes that influence the intensity of psychoactive drugs? (3)

Answer 2

Concentration
Concentration @ site
Way body responds & adapts

Question 3

Primary site of action of psychoactive drugs?

Answer 3

CNS

Question 4

Action on CNS is determined by what psychopharm processes? (ADME+2A)

Answer 4

Absorption
Administration
Action of drug
Distribution
Metabolism
Excretion

Question 5

Doses of psychoactive drugs - 3 types.

Answer 5

Effective
Toxic
Lethal

Question 6

Overdose would be an example of what type of dose…

Answer 6

Lethal

Question 7

This type of administration is slow. Must pass through stomach and into LI

Answer 7

Ingestion (Oral)

Question 8

Fast administration, to blood and directly to bran

Answer 8

Inhalation (Lungs)

Question 9

This type of administration is slow release, no highs and lows

Answer 9

Mucous Membranes

Question 10

Allows for an accurate controlled dose.

Answer 10

Injection (IM,IV,SQ)

Question 11

T/F A drug must physically interact with a cell to produce a change in cell fnxn (change in body fnxn or behaviour)

Answer 11

TRUE

Question 12

The cellular component is referred to as the drug…

Answer 12

Receptor

Question 13

4 Ways psychoactive drugs affect neurotransmission:
Fit
Block
Interfere
Release

Answer 13

Fit into receptor sites (mimic natural chemical) H,LSD CAN
Block receptors & prevent message (PCP)
Interfere with re-uptake (COC)
Release in higher amounts than normal (MA)

Question 14

The desired effect & unwanted responses

Answer 14

Main effect

Side Effect

Question 15

These effects are felt while under influence

Answer 15

Short term effects

Question 16

These effects are felt after drug has been metabolized & excreted

Answer 16

Long term effects

Question 17

Metabolism breaks down drugs 3 ways

Answer 17

Fat soluble -> water soluble, cannot enter brain
Via liver
Bloodstream -> kidneys (filter)

Question 18

Elimination is primarily through..

Answer 18

Urine

Question 19

T/F Small amounts may be excreted via lungs, bile, saliva & breastmilk

Answer 19

TRUE

Question 20

The length of time it takes body to eliminate half the amount of drug

Answer 20

Half Life

Question 21

Enhancing of drug effect?

Answer 21

Synergism

Question 22

Diminishing of drug effect?

Answer 22

Antagonism

Question 23

Reinforcement happens 3 ways. (SPA)

Answer 23

Self-rewarding (high)
Pleasure drive biological force
Activation of pleasure circuits by drug

Question 24

Reduced sensitivity by repeated exposure =

Answer 24

Tolerance - need more to get effect

Question 25

This happens when the drug effect becomes more pronounced in smaller doses.

Answer 25

Reverse Tolerance

Question 26

Reduced sensitivity to a drug due to acquired tolerance of another drug that produces similar effects

Answer 26

Cross tolerance

Question 27

A state in which the use of drug is necessary for physiological or psychological well-being

Answer 27

Dependenc

Question 28

Psychological dependence is characterized by (4)

Answer 28

Continued use to ‘function’
Intense wish to use
Compulsive use/anxiety if unavailable
Conditioned responses (Pavlov Dog)

Question 29

Tissues adjust to presence of drug that when discontinued WD symptoms occure.

Answer 29

Physical Dependence