Psychiatry Seminar: Psychopathology Flashcards

1
Q

Psychopathology

A

Terminology:
- Symptoms vs Syndromes (Cluster of symptoms specific to particular disorder ~heart failure i.e. A disorder defined by symptoms instead of etiology (since etiology cannot be found))
- Disease / Disorder / Diagnosis

Psychopathology:
- Study of abnormal states of mind
- Systematic study of abnormal experience, cognition + behaviour / Study of the products of a disordered mind

Classification:
1. Explanatory (on top of describing the symptoms, also explain underlying mechanism of symptoms e.g. Freud)
- Psychodynamic
- Experimental (doing experiment to delineate cognitive mechanisms that lead to symptoms)

  1. Descriptive (simply describing the symptoms)
    - Observation
    - Subjective experiences
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2
Q

Descriptive psychopathology

A
  • Precise **description + **categorization of abnormal experiences as recounted by patients & and observed in his behaviour
  • Objective description of abnormal states of mind, avoiding as far as possible preconceived ideas or theories (***atheoretical) i.e. avoid theoretical explanations for psychological events
  • Concerned solely with the descriptions of ***conscious experiences + observable behaviours
  • 2 basic components: **observation (e.g. **behaviour) + **empathic assessment of subjective experience (e.g. **mood)

*this approach is also called “phenomenology” (internal / subjective experience)

Object of inquiry:
- Scientific investigation of internal (subjective) experiences of an individual…
- Mind vs. Brain
- Objective vs. Subjective
- A theoretical network meshing “observers”, “patients” & “symptoms together
- Clinicians as “observers” (recognizing patients’ subjective experience)
- Patients as “observers” (own subjective experience)
- Observation + empathic inquiry as a bridge between subjective experience & “object” under examination
- Subjective experience (mood, beliefs etc.) is in fact a reflection or manifestation of underlying neurobiological signal originated in an affected brain site
- Need to tease out layers of psychosocial noises partaking in the process of symptom formation (e.g. manipulation vs disorientation, hallucination)

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3
Q

Why is studying psychopathology important?

A
  • This is the “language” coding for the abnormalities of the mind manifesting via subjective experience or behaviours (The history of mental symptoms)
  • This is the units of analysis elicited in clinical interview and mental state examinations
  • DP is the necessary professional skill for psychiatrists
  • From symptoms to syndromes to diagnoses and disorders, then to disease entities
  • Without understanding what the psychopathologies are, how can you make an accurate diagnosis? (pattern recognition as tradition in medicine)
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4
Q

Dimensions of Psychopathology

A
  1. Form vs Content
  2. Primary vs Secondary
  3. Significance of individual symptoms
  4. Cultural variations in psychopathology
  5. Normal vs Abnormal
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5
Q

Form vs Content

A

Form:
- Description of symptom’s structure in phenomenological terms (e.g. delusion, hallucination: auditory / visual / others)
- Assist in diagnosis

Content:
- Colouring of the experience e.g. being pinpointed by classmates (persecutory delusion)
- Concerned by patient

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6
Q

Primary vs Secondary

A
  1. Temporal
  2. Causal (e.g. delusion of persecution secondary to auditory hallucinations of derogatory content, grandiose delusion secondary to manic episode)
    - Primary: Directly from pathological process
    - Secondary: Reaction to a primary symptom
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7
Q

Significance of individual symptoms

A
  • Key symptoms defining specific syndrome
  • E.g. depressed mood defining depressive disorder, first rank symptom are specific features for schizophrenia
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8
Q

Cultural variations in psychopathology

A
  • Depressed mood vs Somatisation presentation (e.g. Chinese people can present with body ache in depression)
  • Content of delusions derived from cultural + ethnic background e.g. possessed by evil spirits
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9
Q

Normal vs Abnormal

A
  • Statistical? Normal distribution?
  • Cultural / Social standard?
  • Continuum vs Discrete (categorical) model (e.g. depressed mood vs delusion)
  • Distress + Dysfunction (definition of disorder)
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10
Q

***Disorders of Mood

A
  1. Nature
    - Depressed
    - Anxiety
    - Elated
    - Irritable
  2. Variation
    - Labile mood (increased range of variation)
    - Emotional incontinence (extreme variation)
    - Blunted affect (lack of emotional sensitivity: negative symptom)
    - Flattening of affect (reduced range of emotion: negative symptom)
    - Anhedonia (loss of ability to experience pleasure)
  3. Congruity
    - Whether mood state is in keeping with person’s circumstances + thoughts
    - Incongruous **affect (feature of Schizophrenia) e.g. laugh when talking about husband’s death
    - Congruent / Incongruent **
    psychotic symptoms e.g. grandiose delusion in mania, delusion of guilt in depression

Major mood disorders:
1. Depressive disorder
2. Bipolar disorder
- Mania / Hypomania / Depressive episode

  1. Anxiety
    - Psychological component: apprehension + worries (e.g. free-floating anxiety)
    - Somatic component: muscle tension, increased respiratory rate
    - Autonomic component: palpitation, increase sweating, dry mouth (panic attack)
    - Avoidance of danger (Phobia): irrational fear + wish to avoid specific object / situation with anticipatory anxiety (e.g. social phobia, agoraphobia, specific phobia, PTSD with avoidance of reminders of event)
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11
Q

***Disorders of Perception

A
  • Process of being aware of what is presented via sensory organ
  • Can be attended to / ignored but ***cannot be terminated by will
  • Perception vs Imagery (generated within the mind)

Abnormal perception:
1. Sensory distortion
- e.g. heightened intensity (hyperacusis), changed quality (micropsia: smaller than real size)
- Illusion (misperception of external stimuli)
- Hallucination
- Pseudo-hallucination (definition of hallucination not fully met, occurs in internal subjective space (vs external in hallucinations) e.g. heard something in one’s thoughts, not perceived as auditory i.e. not come from ears)

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12
Q

Hallucinations

A
  • ***Perception without external stimuli to corresponding sensory organ
  • 2 exceptions
    —> Functional hallucinations (External stimuli triggering hallucinations e.g. water tap noise trigger 3rd person AH)
    —> Reflex hallucinations (A particular stimuli trigger hallucinations of another sense e.g. water tap noise trigger visual hallucinations)

Types:
- Visual
- Auditory (Elementary vs Complex (e.g. Musical))
- Somatic (Tactile (e.g. Formication (Formite): Sensation of insects crawling under the skin) vs Deep)
- Olfactory
- Gustatory

Healthy people can experience hallucinations occasionally
- **Hypnagogic (from wake to sleep) + **Hypnopompic (from sleep to wake) (Visual / Auditory)
- **After sensory deprivation (blindness, deafness)
- **
Bereavement (grief reaction)
- Neurological disease (e.g. Temporal lobe epilepsy (rubber burning smell), Charles Bonnet syndrome (VH associated with disease of visual pathway))
- VH: may indicate organic condition

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13
Q

Auditory hallucination (AH)

A

Auditory verbal hallucination (AVH):
1. 2nd / **3rd person
2. **
Thought echo
3. **Running commentary
4. **
Discussing among themselves / Conversing with each other
5. Commands (risk of self-harm / suicide)
6. Derogatory

***: First rank symptoms (proposed to be of first rank importance in making a diagnosis of schizophrenia)

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14
Q

***Disorders of Thinking

A

Particular kinds / Contents of thoughts:
1. Delusions
2. Obsessions
3. Over-valued ideas
4. Negative cognition

Stream and Form of thoughts:
- Speed / Pressure of thoughts
- Linking of thoughts together

Possession of thoughts (***Thought alienation: first rank symptom)
- Thought insertion
- Thought withdrawal
- Thought broadcasting

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15
Q
  1. Delusions
A
  • Idea, Belief
  • **Firmly held (Unshakeable / Fully convicted) on **inadequate ground
  • Not affected by ***rational argument / evidence to the contrary
  • Not a conventional belief that the person might be expected to hold given his educational + cultural background
  • NOT defined by true / false (even though 99.9% is false)
  • NOT all or none (a continuum (e.g. might not be true —> probably true —> definitely true))

Dimensions of delusion:
1. Degree of conviction (Partial delusion)
2. Emotional distress (e.g. from persecutory delusion)
3. Preoccupation
4. Acting-out (e.g. confronting by arguing with persecutory delusion)
5. Pervasiveness vs Encapsulation (pervasive across different settings e.g. at school, at work, at home vs encapsulated: at a particular setting only)
6. Bizarreness (e.g. delusional disorders tend to have delusion that is single-theme, non-bizarre, encapsulated, systematised)
7. Systematisation (e.g. delusional thoughts starting to expand to form a system e.g. persecutory delusion from neighbours only to security to teachers to public)
8. Functional level

Karl Jaspers (Concept of understandable):
1. Primary delusion: Not occurring in response to another psychopathological form
2. Secondary delusion: Understandable in present circumstances e.g. pervasive depressive mood state / AH-triggered off abnormal belief

Primary delusions:
1. Delusional intuition (autochthonous, out of the blue)
2. **Delusional perception (abnormal significance attached to a real percept without any cause that is understandable in rational / emotional terms, momentous, of overwhelming personal significance)
3. Delusional atmosphere (mood)
4. Delusional memory (retrospective delusion)
**
: First rank symptom

Content of delusions:
- Persecutory (most common)
- Referential (most common)
- Grandiose (identity / ability)
- Delusion of infidelity / jealousy
- Delusion of love / erotomanic delusion (usually subject is of higher status than patient)
- Delusion of poverty and guilt
- Nihilistic delusion (Cotard’s syndrome) (associated with very severe depression)
- Hypochondriacal delusion (belief of suffering from a disease)
- Dysmorphophobic delusion (belief of disfigurement of face)
- Delusions of misidentification (Capgras (belief that a close person has been replaced by an identical imposter i.e. faked) / Fregoli delusions (an unfamiliar person as a familiar person))
- Shared delusions (Folie a deux) (delusions transmitted from one person to another)
- **Delusion of control (passivity)
- **
Thought alienation (thought withdrawal, insertion, broadcasting)

***first rank symptoms

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16
Q
  1. Over-valued ideas
A
  • Isolated preoccupying belief
  • Neither delusional nor obsessional in nature (although some overlap with delusion)
  • Dominating person’s life, affecting his actions
  • e.g. Anorexia nervosa
17
Q
  1. Obsession (and Compulsion)
A
  • ***Recurrent, persistent thoughts, impulses, doubts, images that enter the mind despite efforts to exclude them
  • Distressing, Unpleasant (Egodystonic) (Patient will have ***insight)
  • Originating from his ***own mind (rather than Thought insertion)
  • Regarded as ***senseless / absurd
  • Associated with anxiety
  • Mostly accompanied with ***compulsive acts relevant to an obsession e.g. checking rituals, repeated hand-washing etc.

Forms:
1. Obsessional thoughts (words, phrases)
2. Obsessional doubts (uncertainty about previous actions)
3. Obsessive ruminations (themes of a more complex kinds e.g. ending of the world)
4. Obsessive impulses (urge to carry out actions)
5. Obsessive phobia

Themes / Content:
1. Dirt and contamination
2. Orderliness
3. Illness
4. Aggression
5. Sex
6. Religion

Compulsive rituals:
1. Checking
2. Cleaning
3. Counting rituals

18
Q
  1. Negative cognition (Pessimnistive thoughts) in depressive disorder
A

Cognitive triad for depression
1. Sense of guilt / self-blame (Past) (Delusion of guilt: Mood congruent)
2. Sense of worthlessness / uselessness (Present)
3. Sense of hopelessness (Future) (Very important predictor for suicidal ideation —> suicide attempt)

19
Q

Stream and Form of thoughts

A

Stream of thoughts (linking up of ideas):
1. Thought block
2. Pressure of speech (more akin to mania)
3. Poverty of speech (thoughts) / Retardation (negative symptoms)
4. Perseveration (repeated thought, indicative of organic cause e.g. dementia, lesion of PFC)

Form of thoughts:
1. Flight of ideas (have logical links but too fast) (Mania)
2. Loosening of association (derailment, no observable logical links at all, tangential response, cannot reach goal) (Schizophrenia)
3. Word salad
4. Circumstantial thinking (too much background / unnecessary detail, can reach goal)
5. Others
- Neologism
- Over-inclusion
- Concrete thinking

20
Q

Depersonalisation and Derealisation

A

Depersonalisation (人格解體 / 失自我感): A change of **self-awareness such that the person feels **unreal, ***detached from his own experience + unable to feel emotion (使人覺得在觀察自己的行為)

Derealisation (失現實感): A similar change in relation to the **environment such that **objects appear unreal, ***people appear as lifeless, 2-dimensional card-board figures (感受到周遭環境不真實)

  • Both are described by patients as highly ***unpleasant
  • Not uncommon in ***mood disorders even in psychotic disorders
  • Quite common as transient phenomena in healthy individuals esp. when tired
21
Q

Motor signs in psychiatric disorders

A

Grouped together —> ***Catatonia: a syndrome not specific to any particular psychiatric disease e.g. schizophrenia, more common in mood disorders, can occur in neurological conditions / medication-induced

Examples:
1. Tics
2. Mannerism (repeated movements with some functional significance)
3. Stereotypes (repeated movements without obvious significance)
4. Posturing (adoption of an unusual body posture continuously for a long time)
5. Waxy flexibility (person’s limbs can be placed in a position in which they remain for long periods)
6. Negativism (person does the opposite of what is asked and actively resist efforts to persuade them to comply)
7. Echopraxia (imitation of an interviewer’s movement automatically even when asked not to do so)
8. Ambitendance (alternate between opposite movements and so on repeatedly)

Treatment:
- BDZ
- ECT

22
Q

Disorders of the Awareness of the Body / Physical complaints without identifiable organic causes

A
  1. Somatic complaint without identifiable organic cause (somatisation)
  2. Hypochondriasis (disease)
  3. Dysmorphophobia (bodily shape or form)
  4. Distorted body image as in AN
  5. Conversion (dissociation) (hysteria 歇斯底里)
    - Symptoms are psychogenic; causation thought to be unconscious; symptom may carry some sort of an advantage to the patient (secondary gain)
    - Mass hysteria

Intentional production or feigning of symptoms:
1. Malingering (with external reward)
2. Factitious disorder (attributed to a sick role)

23
Q

Insight

A
  • Can be partial (not an all-or-none phenomenon / dimensional construct)
  • State or Trait?
  • Key feature in **Psychotic disorders, **Mania

Assessing insight:
1. Is an individual **aware of phenomenon that others have observed?
2. Does he recognize the phenomenon as **
abnormal?
3. Does he consider the phenomenon caused by **mental illness?
4. **
Consequence of illness
5. Does he think that he needs ***treatment?

24
Q

Disorders of Memory + Consciousness

A

Disorders of consciousness:
1. Disorientation, stupor, confusion (better avoid using as the term is imprecise)
2. Delirium (to replace acute confusional state) (can have hallucination but cannot be regarded as schizophrenia)

Memory:
- Immediate registration
- Short-term memory
- Recent memory
- Long-term memory

Process:
- Registration, Retention, Retrieval, Recall, Recognition

Disorders of memory:
1. Amnesia
- Retrograde / Antegrade amnesia

  1. Identifying paramnesia
    - Jamais vu (failure to recognize events that have been encountered before)
    - Déjà vu (conviction that an event repeats one that has been experienced in the past when in fact it is novel)
  2. Confabulation
    - falsification of memory occurring in clear consciousness (associated with amnesia —> fill the memory gaps)
    - suggestibility as a prominent feature (a person will accept the suggestions of another person)