Psychiatry MNTH Flashcards
Criteria for Bipolar 1 diagnosis
One week of elevated or irritable mood. At least three of: Grandiosity Decreased need of sleep Talkative Flight of ideas Distractibility Impulsivity Agitation
Then needs to be serious enough for severe functional consequences/hospitalization
What is the best treatment for Mania?
Lithium
Quetiapine
Divalproex
Treatment for Bipolar 1 depression
Can you use SSRI or SSNRI?
Quetiapine
No, it can lead to a bout of mania.
What is the best pharmalogical Tx for Bipolar 1 maintenance?
Quetiapine
Lithium
Lamotrigine
How is a bipolar 2 Dx different from a bipolar 1 Dx?
Hypomania instead of mania+ the current or past depression
The hypomania must last for at least 4 days.
Same need of 3 of 7 things
Not severe enough for hospitalization.
Tx for Bipolar type 2?
Quetiapine
Lithium
Lamotrigine
What is Cyclothymia?
Numerous periods with hypomanic symptoms over at least two years.
The full criteria for hypomania or depression are never met.
Which bipolar drugs are indicated and contraindicated during pregnancy?
Quetiapine is the agent of choice
Depakote is ALWAYS contraindicated for neural tube defects
Lithium is contraindicated in the 1st trimester due to Epstein’s Anomaly
What is catatonia, how is it diagnosed, and how is it treated?
Waxy Flexibility, impulsivity, posturing, rigidity
Diagnosed with a Busch-Francis Scale and a lorazepam challenge
Treated with high-dose benzodiazepines and/or ECT (Electroconvulsive Therapy)
What is the criteria for a Dx of Major Depression?
5 of the following over a 2-week period with changes from previous function.
Sleep Disturbance Interest Decreased Guilt Energy changes Concentration Appetite or weight increase or decrease Psychomotor changes Suicidal Ideation
What is Dysthymia?
Sub clinical chronic depressive disorder lasting at least 2 years.
Doesn’t meet criteria for major depression
What is Premenstrual Dysphoric Disorder?
Meets the symptoms of Major Depression plus must be present in the final week before menses onset and improve within days of onset of menses.
What are Pharmacological and Non-pharmacological Tx for Major Depressive Disorder?
SSRIs, SSNRIs, Mirtazapine, Bupropion
Cognitive Behavioral Therapy
Psychotherapy
Transcranial Magnetic Stimulation
Electroconvulsive Therapy
Which populations are at high risk for MMD?
Postpartum Women Those with family history Advanced Age Neurological Disorders Physical Illness
DSM-5 Criteria for Schizophrenia?
Two or more of the following for at least 6 months (one must be from first 3)
Delusions Hallucinations Disorganized speech Disorganized or catatonic behavior Negative symptoms (lowered emotional expression or abolition)
Must show severe loss of function.
What are the four dopamine pathways involved with SCZ?
Mesolimbic: Increase in DA causes Positive symptoms
Mesocortical: DA hypoactivity: negative and cognitive symptoms
Nigrostriatal: Drugs- EPS and TD drug side effects
Tuberohypophyseal: Drugs- Hyperprolactinemia
Dx criteria for Schizophreniform Disorder?
Same as SCZ by for duration of 1-6 months.
What is the treatment for Psychotic disorders?
D2 Blockers
LAIs for SCZ or if you are worried about compliance
Drugs to treat specific symptoms (depression, mood, anxiety)
Criteria for a delusional disorder?
One or more delusion with a duration of at least 1 month
Criteria for SCZ not met
Function isn’t impaired outside of direct impact of delusions.
What are the types of hallucinations and which disorders are they linked with?
Auditory: Psychosis Visual: Neurological syndromes Tactile: Drug withdrawal Olfactory: CNS lesion Hypnagogic/hynapompic: Sleep disorders
What are the primary and secondary psychotic disorders?
Primary: SCZ, Delusional disorder, brief psychotic disorder
Secondary: Substance-induced, due to another medical condition.
What is a schizoaffective disorder?
An uninterrupted period of illness in which there is a major mood episode concurrent with Criterior A of schizophrenia.
Delusions or hallucinations for 2 weeks or more in the absence of a major mood episode
These are overdiagnosed.
What are the components of a mental status exam?
Appearance Attitude Speech Mood Affect Though process Though content Perceptions Cognition Insight Judgment Reliability
In a mental exam, which items are added to your ROS always?
Anxiety Mood Psychosis Substance Use- Specific SI/HI
Experiments of Harry Harlow?
Monkeys deprived of contact w/ mothers. They chose cloth over food.
Studies of Mary Ainsworth?
Strange Situation Test
- Anxious-Avoidant Insecure Attachment: Avoids or ignores caregiver, won’t explore
- Secure Attachment: Explores w/ caregiver, upset when they leave
- Anxious Resistant Insecure Attachment: Distress even before separation and hard to comfort on return
Theories of Konrad Lorenz
Imprinting
Theories of John Bowlby?
Maternal Deprivation Theory: No mother causes trouble
Built off Lorenz
What are the 8 virtues of Erik Erickson?
Hope, Basic Trust vs Basic Mistrust 0-18 months
Will, Autonomy vs Shame 1-3 years
Purpose Initiative vs guilt 3-5 years
Competence, Industry vs Inferiority 6-11 years
Fidelity, Identity vs Role Confusion 12-18 years
Love, Intimacy vs Isolation 18-40 years
Care, Generativity vs Stagnation: 40-65 years
Wisdom, Ego Integrity vs Despair: 65+
What are the 4 stages of Stage Theorists?
What are the Hallmarks of each stage?
Sensorimotor 18-24 months
- Object permanence
Preoperational 24 months to 7 years
- Symbolic thinking
Concrete operational: 7-11 years
- Acquisition of Conservation Hallmark
Formal Operational Adolescence to Adulthood
-Abstract thinking, creativity, Third eye question
What are the psychosocial stages and what changes can trauma make to them?
Whose theory is this?
Sigmund Freud
Oral 0-2 Anal 2-3 Phallic 3-7 Latency 7-11 Sexual 11+
Trauma can cause fixation or regression on or to different stages.
What are the three types of anxiety based on Freud’s theories?
Neurotic Anxiety: Worry we loose control of the Id (our compulsions)
Reality Anxiety: Fear of real world events (dog bite)
Moral Anxiety: Fear of violating our own moral principles
Define a panic attack
Abrupt onset of intense fear or discomfort that peaks in minutes with at least 4 of the following:
Palpitations Sweating Short of breath Chest pain Dizziness Paresthesias Fear of loss of control Shaking Sensations of choking Nausea Chills Fear of dying
Trypanophobia Algophobia Glossophobia Ophidiophobia Nosecomephobia Arachnophobia Coulrophobia Iatrophobia
Fear of needles Fear of pain Fear of public speaking Fear of snakes Fear of hospitals Fear of spiders Fear of clowns Fear of doctors
How much is spent on anxiety each year?
42 billion
Social Anxiety Disorder DSM-5
Marked anxiety about humiliating or emabarrassing yourself in social situations for at least 6 months.
Symptoms are out of proportion to the threat
Specific Phobia
Perisitent unreasonable excessive fear cause by the presence or anticipation of a specific object or situation
Can cause panic attacks
The object or situation is generally avoided
May become GAD
Agoraphobia
Intense anxiety to or in anticipation of entering two or more situations where the person feels stuck, unable to escape, or not able to get help
Public transport Open areas Closed areas Lines or crowds Alone outside the house
For at least 6 months, fear out of proportion
Panic Disorder DSM
What is the only single social trigger?
Recurrent unexpected panic attacks followed by one or both of the following for 1 month:
Persistent concern of having more panic attacks
Maladaptive change in behavior in response to the panic attacks
Divorce/separation
Generalized Anxiety Disorder DSM-5
Excessive anxiety and worry about a number of activities or events in multiple contexts on a near daily basis for 6 months with three of the following:
Restlessness Fatigue Poor concentration Muscle tension Irritability Sleep disturbance
Explain the Tx of GAD
Trusting relationship
Cognitive behavioral therapy
Exercise
SSRIs/Benzodiazepines
- Low dosage, slow titration
What are some medical conditions with anxiety-like symptoms?
CAD, CHF, Arrhythmia, PE Asthma, pneumonia Thyroid dysfunction, Menopause, Cushing disease, Anemia Seizure disorder Substance Abuse
What are indications and contraindications of use of Benzodiazepines in anxiety disorders?
Indications:
Rapid symptom control
Lack of effect of multiple antidepressants
Infrequent symptoms
Contraindications/Risks: Chronic opiate therapy Subastance abuse disorder Memory impairment Elderly
Criteria for PTSD
Exposure to actual physical or sexual trauma With one from each group 1. Negative alterations in mood 2. Hyperarousal: Hypervigilence 3. Avoidance 4. Intrusion symptoms: Nightmares
All more than 1 month duration with impaired function
What is the treatment for PTSD?
Psychotherapy, Exposure Therapy
SSRI, SNRI, Prazosin, Clonidine, Quetiapine, TCA
Not Benzos
Acute Stress Disorder
Criteria are the same as PTSD but apply only if 3-30 days have elapsed.
Adjustment Disorder
Emotional or behavioral symptoms in response to an identifiable stressor occurring within 3 months of the onset of the stressors.
Distress out of proportion with significant impairment.
Once the stressor is gone, the symptoms leave within 6 months.
No anhedonia, they still enjoy the things they love unlike MDD