Psychiatry - Differential diagnoses Flashcards

1
Q

What symptoms does the anxious patient present with?

A

Emotions: anxiety, tension, irritability

Cognitions: exaggerated fears and worries

Behaviour: avoidance of feared situation, checking, seeking reassurance

Somatic features: tight chest, hyperventilation, palpitations, decreased appetite, nausea, tremor, aches and pains, insomnia, frequent desire to urinate

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2
Q

What differential diagnosis should be considered in the anxious patient?

A
Psychiatric:
GAD
Panic disorder
Phobias
OCD
PTSD
Acute stress reaction
Depression
Substance misuse - esp withdrawal syndromes 
Personality disorder
Dementia 
Medical:
Hypoglycaemia 
Hyperthyroidism
Phaeochromocytoma 
Delirium
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3
Q

Management of the anxious patient

A

Psychiatric history and MSE
Exclude medical causes - blood pressure, glucose, FBC, TFT
Acute anxiety may be relieved by anxiolytics - e.g. BDZ, but for short courses only as patients may become dependent on them if they are used long term
Certain antidepressants can be used for treatment of anxiety disorder, even if the patient is not depressed - e.g. citalopram for panic disorder, and venlafaxine for GAD
CBT

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4
Q

What symptoms would a depressed patient present with?

A

Core features: persistent low mood, anhedonia, anergia

Cognitive features: decreased concentration and attention, low self-esteem, bleak and pessimistic views of the future, feelings of guilt or worthlessness, ideas of self harm or suicide

Somatic features: poor sleep, early morning wakening, decreased appetite leading to weight loss, decreased libido, constipation, amenorrhoea, diurnal variation of mood, psychomotor retardation

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5
Q

Differential psychoses to consider in the depressed patients

A
Psychiatric:
Depression
Severe depression with psychotic symptoms
Bipolar affective disorder
Anxiety disorder
PTSD
Schizophrenia
Schizoaffective disorder
Dementia 
Substance misuse (chronic alcohol misuse)
Personality disorder 
Medical:
Hypothyroidism
Cushing's syndrome
Hypercalcaemia (malignancy)
Infections (HIV, syphilis)
MS
PD
Medication (sedatives, anticonvulsants, beta blockers)
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6
Q

Management of the depressed patient

A

Psychiatric history and MSE (assess for suicidal ideation and manic and psychotic features)
Exclude medical causes
Antidepressants
CBT

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7
Q

What features might the elated patient present with?

A

Main features: elevation of mood, overactivity, pressure of speech, disinhibition

Other features: irritability, flight of ideas, distractibility, grandiose ideas, decreased sleep, impaired judgment, irresponsibility, decreased appetite

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8
Q

What differential diagnoses should be considered in patients presenting with elated mood?

A
Psychiatric:
Hypomania
Mania
Mania with psychotic symptoms
Schizoaffective disorder
Schizophrenia
Acute intoxication with cocaine or amphetamines 
Acute and transient psychotic disorder 
Medical:
Brain disorders affecting the frontal lobes (e.g. space occupying lesion, dementia, HIV, syphilis, infection)
Alcohol withdrawal
Corticosteroids
Anabolic androgenic steroids
Hyperthyroidism
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9
Q

Management of the elated patient

A

Psychiatric history and MSE
During the interview maintain a calm, non confrontational manner. Manic patients may become aggressive, or violent in response to even minor irritations
Exclude other medical causes
Antipsychotics and benzodiazepines are used in acute episodes
Lithium and other mood stabilisers are used as prophylaxis in bipolar effective disorder
ECT can be used in severe cases of mania resistant to other treatment

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10
Q

What symptoms might a hallucinating patient present with?

A

Auditory, visual, somatic olfactory, or gustatory hallucinations. Auditory and somatic are more likely in psychiatric disorders, while visual and olfactory suggest an organic disorder

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11
Q

Differential diagnosis to consider in the hallucinating patient

A
Psychiatric:
Schizophrenia
Schizoaffective disorder
Delusional disorder
Mania with psychotic symptoms 
Severe depression with psychotic symptoms 
Acute and transient psychotic disorder 
Alcohol and drug misuse - e.g. hallucinogenic drugs, LSD, magic mushrooms 
DT 
Medical:
Temporal lobe epilepsy
SOL
Delirium 
Metabolic disturbances, liver failure
Infection - e.g. encephalitis 
Head injury
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12
Q

Management of the hallucinating patient

A

Psychiatric history and MSE (including risk assessment)
Exclude organic causes
Antipsychotic drugs for psychosis
Consideration should be given to admitting the patient to hospital

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13
Q

Symptoms that the obsessive or compulsive patient may present with

A

Obsessions = unwanted, distressing thoughts or images that enter the patients mind even though they try to resist them. The thoughts are recognised as the patients own

Compulsions = acts performed to ease the anxiety caused by obsessions and become repetitive and are recognised as senseless

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14
Q

Differential diagnosis in the obsessive or compulsive patient

A
OCD
Anakastic personality disorder 
Depression
Schizophrenia
Anorexia nervosa
Phobic disorders
Tourette's syndrome
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15
Q

Management of the obsessive/ compulsive patient

A

Psychiatric history and mental state examination
Consider if there is any other symptoms that might suggest depression or psychosis
Antidepressants - clomipramine and SSRIs have the greatest efficacy
CBT

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16
Q

How might the unresponsive patient present?

A

Alert with eye movements only
Mutism (absent speech)
Absent movements
Decreased attention span for environmental stimuli
Speech may be present but there may be amnesia for personal identity and history

17
Q

Differential diagnoses to consider in the unresponsive patient

A
Psychiatric:
Schizophrenia (catatonic state)
Depression (depressive stupor)
Neuroleptic malignant syndrome 
Dissociative disorders 
Medical:
Hypoglycaemia 
Delirium
Encephalitis
PD
Cerebrovascular accident 
Acute intoxication, e.g. alcohol, solvents
18
Q

How do you manage the unresponsive patient?

A

ABC
Exclude life threatening brain pathology
Check vital observations - BP, pulse, GCS
Initially obtain a brief history from an informant (? known psychiatric illness, medication, illicit substances; is the patient deaf and/or blind? what languages does the patient speak?)
Perform a complete physical exam
Perform investigations guided by history and examination
Ensure adequate hydration
Once life threatening brain pathology has been excluded, obtain a full history from an informant, obtain old notes and attempt MMSE on the patient
Admit the patient; further management will depend on the underlying aetiology