psychiatry Flashcards

1
Q

mesocortical dopamine hypoactivity

A

negative symptoms in schizophrenia

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2
Q

subcortical dopamine hyperactivity

A

psychosis

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3
Q

prolactin dopamine pathway

A

tuberoinfundibular

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4
Q

extrapyramidal dopamine pathway

A

nigrostriatal

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5
Q

motivation and reward pathway

A

mesolimbic system

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6
Q

mesolimbic DA blockade

A

depression

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7
Q

mesolimbic DA agonism

A

psychosis

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8
Q

Clozapine SEs

A

agranulocytosis

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9
Q

clozapine prescribing

A

check 2 other anti-psychs then consultant can Rx

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10
Q

clozapine monitoring

A

once a week for 6/12 then once every 2 weeks for 6/12 then every 4 weeks thereafter then one month after discontinuation

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11
Q

brain changes in schizophrenia

A

reduced frontal volume, enlarged ventricles and reduced grey matter in temporal cortex

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12
Q

pressure of thought

A

abundance of ideas

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13
Q

poverty of thought

A

patient reports lack of thought

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14
Q

thought block

A

abrupt stop of stream - schizophrenia

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15
Q

flight of ideas

A

move between topic with link

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16
Q

knights move thinking

A

move between topics without link

17
Q

treat EPSE

A

procyclizine

18
Q

Mx OCD

A

SSRI
SSRI
TCA/SSRI

19
Q

borderline learning disability

A

70-80

20
Q

mild LD

A

50-69

21
Q

moderate LD

A

35-49

22
Q

severe LD

A

20-34

23
Q

profound LD

A

<20

24
Q

alcohol withdrawal

A

chloriazepoxide

25
Q

mild depression criteria

A

> 4 symptoms, 2-3 core sx

26
Q

moderate depression

A

5-6 symptoms

27
Q

severe depression

A

> 7 sx

28
Q

core symptoms of depression

A

fatigue, low mood, loss of enjoyment

29
Q

alcohol withdrawal seizures happen within

A

48 hours

30
Q

delerium tremens within

A

48-72 hours

31
Q

eosinophilic inclusions

A

Lewey bodies