Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

3MB EXAM NOTES > Psychiatry > Flashcards

Psychiatry Flashcards

1
Q

Safest SSRI for cardiac issues?

A

Sertraline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Safest SSRI for epilepsy but associated with long QTC?

A

Citalopram

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

SSRI voided when using Tamoxifen & due to anticholinergic effects & intense discontinuation syndrome?

A

Paroxetine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Examples of SNRIs?

A

Venlafaxine & Duloxetine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which alpha receptor does Mirtazepine block?

A

alpha 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is a rare side effect of Mirtazepine?

A

Blood dycaryosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which antidepressant is first line if the patient has isnomnia & poor appetite?

A

Mirtazepine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which antidepressant class precipitates a “cheese reaction” or Hypertensive crisis & why?

A

MAO inhibitors (Phenelzine, Moclobemide) as accumulation of tyramine causes norepinephrine accumulation.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How do you manage a “cheese reaction” or Hypertensive crisis? What causes this?

A

Phentolamine infusion

MAO inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How do you manage neuroleptic malignant syndrome?

A

Bromocriptine (dopamine agonist reverses effects of antipsychotics - they work by inhibiting dopamine)
plus Diazepam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What drugs cause neuroleptic malignant syndrome?

A

Antipsychotics (Chlorpromazine, Quietiapine)
Levodopa
Benzodiazepenes (Haloperidol)
Metclopramide (prokinetic - also exacerbates parkinson’s)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which antidepressant is known for causing overflow incontinence

A

Amytriptilline due to anticholinergic effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which class of antidepressant is cardiotoxic in overdose & should be avoided in those with suicidal intent?

A

Tricyclics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the main side effects of atypical antipsychotics

A
  1. Motor: Parkinsonism, Acute dystonia, Akathisia & Tardive dyskinesia (extrapyramidal effects)
  2. Venous/cardiac: Increase risk of stroke/VTE in elderly, Qtc prolongation
  3. Metabolic syndrome (hyperlipidaemia, hyperprolactinaemia Etc.)
  4. Weight gain & sedation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What do the terms Acute dystonia, Akathisia & Tardive dyskinesia mean? Which class causes them?

A

Acute dystonia is sustained muscle contraction
Akathisia is severe restlessness
Tardive dyskinesia is involuntary choreoathetoid movements
Antipsychotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the first line recommendation for schizophrenia?

A

Olanzapine

17
Q

When is Clozapine used in the management of schizophrenia?

A

If the patient is resistant to at least two other anti-psychotics for at least 6-8weeks

18
Q

If Clozapine has been missed for >/48hours it must be titrated upwards from the starting dose (12.5mg) T/F?

A

True, can be titrated faster than in a clozapine niave patient, however

19
Q

Smoking cessation increases levels of Clozapine in the body T/F?

A

True

20
Q

Why is a baseline ECG required before starting Clozapine?

A

Assess risk of developing Myocarditis (adverse effect of C.)

21
Q

What symptoms MUST patients report during Clozapine use?

A

Infection (agranulocytosis)
Constipation
Fast heart beat (myocarditis)

22
Q

Aside myocarditis & agranulocytosis, what other significant side effects does Clozapine have?

A

Reduces seizure threshold
Huge weight gain & highly sedative
Hypersalivayion

23
Q

What is the first line maintenace therapy for bipolar?

A

Lithium

24
Q

If Lithium can’t be used, what are the options for maintenace therapy in bipolar?

A

Sodium valproate - but avoid in women of child-bearing age
Antipsychotics - but avoid in endocrine problems & obesity
Lamotrigine

25
Q

Manging an acute manic episode?

A
  1. Discontinue antidepressants
  2. Control symptoms - benzodiazepenes
  3. Atypical antipsychotic - olanzapine, quietiapine, resperidone
26
Q

Managing an acute depressive episode in bipolar?

A
  1. Must use antidepressants WITH an antipsychotic - olanzapine & fluoxetine.
  2. Can use quietiapine alone.
27
Q

Side effects of Lithium?

A

Endocrine: Hypothyroidism, thyroid enlargement, HYPERparathyroidism, hypercalcaemia
Renal: nephrotoxicity
Leucocytosis, weight gain, idiopathic intracranial hypertension.
GI: nausea, vomiting, diarrhoea

28
Q

How does lithium affect ECG findings?

A

T wave flattening or inversion

29
Q

What is an acute dystonic reaction & how is it managed?

A

Muscle spasms lasting hours - days

Prochlorperazine or Procyclidine

3MB EXAM NOTES (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions