Psychiatry Flashcards
What are the main methods by which antidepressants work ?
Increasing synaptic availability of N-AD/ Serotonin (5HT)
How do SSRI Works?
SSRIs work by increasing serotonin levels in the brain.
SSRIs inhibit serotonin reuptake by nerve cells so more serotonin is available to pass further messages between nearby nerve cells.
Name some SSRIs?
Effective For Sadness Panic Compulsions
escitalopram fluoxetine sertraline paroxetine citalopram fluvoxamine
Non-pharmacological Tx for depression?
Exercise Counselling Meditation- Yoga, Tai Chi Social Clubs Psychotherapy
Therapy is know to be as effective as anti-depressants in mild/moderate depression.
Common Side effects of anti-depressants?
Hyponatremia GI disturbance Insomnia Sexual dysfunction Weight gain Dry mouth Headaches Agitation/Restlesness/Anxiety
Causes for violent behaviour?
Psychiatric illness, substance misuse, personality disorder, physical illness
Adverse environments
What environmental changes may trigger violence in patients
Overcrowding Noise Alienation Claustrophobia Removal of privileges - due to bad behaviour
Define rapid tranqulisation?
Use of medication in controlling behaviour. Used as a last resort
Examples of antipsychotics
Haloperidol Olazapine Quetiapine Aripiprazole Risperidone Clozapine
What are the 3 Major criteria points for a depression diagnosis?
Time period for the criteria?
Persistent sadness or low mood; and/or
Loss of interests or pleasure (Anehdonia)
Fatigue or low energy (Anergia)
At least 1 of these, most days, most of the time for at least 2 weeks.
DSM-V
<5- SUBTHRESHOLD DEPRESSION
> 5 SIGECAPS + ONGOING FOR 2 WEEKS (MOST DAYS)
Symptoms of depression?
Time period?
Sleep Appetite Concentration Low confidence Suicidality Agitation Slowing of movements Guilt
Symptoms should be present for a month or more and every symptom should be present for most of every day.
What area of the brain deals with initiating muscle contractions?
Basal ganglia
What should you consider when doing a Mental State Examination?
Appearance Speech Memory/mood Thoughts Perception Orientation
Always Send Mail Through Post Office
MSE - Appearance
What things do you think about?
- Eye contact and rapport
- Clothing
- Hygiene
- Facial expressions
- Motor behaviours
- Signs of autonomic arousal
- Affect
Define Affect?
How people convey their mood by their behaviour
e.g. reactive and appropriate - that is, laughs at a joke, or cries when sad.
MSE - Speech
What things do you think about?
Content
Volume
Form - Speech rate, rhythm, fluency of speech
MSE - Mood
What things do you think about?
Elevated / Depressed?
Ask the patient to describe their mood subjectively?
Enquire about other mood states such as anxiety and panic?
MSE - Perceptions
What things do you think about?
Hallucinations? - Type/Origin
Delusions?
Define Delusion?
“A delusion is a false, unshakeable idea or belief which is out of keeping with the patient’s educational, cultural and social background; it is held with extraordinary conviction and subjective certainty.”
MSE - Orientation/Cognition
What things do you think about?
Orientation- time, person and place
General knowledge - name of prime minister, recent news items etc.
Concentration and attention? - Spelling WORLD backwards or serial sevens
Recall - repeating the new information five minutes later
Registrations - ability to repeat new information such as a name and
address
What’s the lifetime prevalence of mental illness?
25%
1 - What are the common types of mental disorder (6) ?
2 - Which is the most common?
1 - Affective disorders, dementia, psychoses, substance misuse, personality disorder, anxiety disorders (panic/OCD/PTSD)
2 - Affective (Mood) disorders
- Depression
- Bipolar
What is bipolar depression also known as
Manic Depression
What is mood congruence? Give examples
Symptoms experienced are in agreement with the person’s current mood.
e.g. Feeling suicidal when your dog dies
Believing you have superpowers when you are going through a manic episode