Psychiatry Flashcards

1
Q

What are the main methods by which antidepressants work ?

A

Increasing synaptic availability of N-AD/ Serotonin (5HT)

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2
Q

How do SSRI Works?

A

SSRIs work by increasing serotonin levels in the brain.

SSRIs inhibit serotonin reuptake by nerve cells so more serotonin is available to pass further messages between nearby nerve cells.

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3
Q

Name some SSRIs?

A

Effective For Sadness Panic Compulsions

escitalopram
fluoxetine
sertraline
paroxetine
citalopram
fluvoxamine
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4
Q

Non-pharmacological Tx for depression?

A
Exercise
Counselling
Meditation- Yoga, Tai Chi
Social Clubs
Psychotherapy

Therapy is know to be as effective as anti-depressants in mild/moderate depression.

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5
Q

Common Side effects of anti-depressants?

A
Hyponatremia 
GI disturbance
Insomnia
Sexual dysfunction 
Weight gain
Dry mouth
Headaches 
Agitation/Restlesness/Anxiety
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6
Q

Causes for violent behaviour?

A

Psychiatric illness, substance misuse, personality disorder, physical illness
Adverse environments

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7
Q

What environmental changes may trigger violence in patients

A
Overcrowding
Noise
Alienation
Claustrophobia 
Removal of privileges - due to bad behaviour
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8
Q

Define rapid tranqulisation?

A

Use of medication in controlling behaviour. Used as a last resort

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9
Q

Examples of antipsychotics

A
Haloperidol
Olazapine
Quetiapine
Aripiprazole
Risperidone
Clozapine
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10
Q

What are the 3 Major criteria points for a depression diagnosis?

Time period for the criteria?

A

Persistent sadness or low mood; and/or
Loss of interests or pleasure (Anehdonia)
Fatigue or low energy (Anergia)

At least 1 of these, most days, most of the time for at least 2 weeks.

DSM-V

<5- SUBTHRESHOLD DEPRESSION

> 5 SIGECAPS + ONGOING FOR 2 WEEKS (MOST DAYS)

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11
Q

Symptoms of depression?

Time period?

A
Sleep
Appetite
Concentration
Low confidence
Suicidality
Agitation
Slowing of movements
Guilt

Symptoms should be present for a month or more and every symptom should be present for most of every day.

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12
Q

What area of the brain deals with initiating muscle contractions?

A

Basal ganglia

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13
Q

What should you consider when doing a Mental State Examination?

A
Appearance 
Speech
Memory/mood
Thoughts
Perception
Orientation

Always Send Mail Through Post Office

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14
Q

MSE - Appearance

What things do you think about?

A
  • Eye contact and rapport
  • Clothing
  • Hygiene
  • Facial expressions
  • Motor behaviours
  • Signs of autonomic arousal
  • Affect
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15
Q

Define Affect?

A

How people convey their mood by their behaviour

e.g. reactive and appropriate - that is, laughs at a joke, or cries when sad.

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16
Q

MSE - Speech

What things do you think about?

A

Content
Volume
Form - Speech rate, rhythm, fluency of speech

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17
Q

MSE - Mood

What things do you think about?

A

Elevated / Depressed?

Ask the patient to describe their mood subjectively?

Enquire about other mood states such as anxiety and panic?

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18
Q

MSE - Perceptions

What things do you think about?

A

Hallucinations? - Type/Origin

Delusions?

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19
Q

Define Delusion?

A

“A delusion is a false, unshakeable idea or belief which is out of keeping with the patient’s educational, cultural and social background; it is held with extraordinary conviction and subjective certainty.”

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20
Q

MSE - Orientation/Cognition

What things do you think about?

A

Orientation- time, person and place
General knowledge - name of prime minister, recent news items etc.
Concentration and attention? - Spelling WORLD backwards or serial sevens
Recall - repeating the new information five minutes later
Registrations - ability to repeat new information such as a name and
address

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21
Q

What’s the lifetime prevalence of mental illness?

A

25%

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22
Q

1 - What are the common types of mental disorder (6) ?

2 - Which is the most common?

A

1 - Affective disorders, dementia, psychoses, substance misuse, personality disorder, anxiety disorders (panic/OCD/PTSD)

2 - Affective (Mood) disorders

  • Depression
  • Bipolar
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23
Q

What is bipolar depression also known as

A

Manic Depression

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24
Q

What is mood congruence? Give examples

A

Symptoms experienced are in agreement with the person’s current mood.

e.g. Feeling suicidal when your dog dies
Believing you have superpowers when you are going through a manic episode

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25
What is mood incongruence? Give examples
Symptoms experienced are conflicting with the person's current mood. e.g. Laughing when your dog dies Believing you have superpowers despite going through a major depressive episode
26
Define Dysthymia?
Mild chronic depression. Symptoms are not severe enough to meet criteria for a mild depressive disorder.
27
What are the the 4 distinctions of depression
Mild, Moderate, Severe, Psychotic (Delusions/Hallucinations) - Should be used to classify a single depressive episode. Further episodes = Recurrent depressive disorder, with an episode of X Mild - 5 SIGECAPS (At least 1 core) - Minor functional impairment Moderate - Functional impairment between mild and severe Severe - Most symptoms present, Severe functional impairment that interferes with normal function +/- psychotic symptoms
28
What are some differential diagnoses for depression?
``` Hypothyroidism, Cushing syndrome Dysthymia Cyclothymia Bipolar disorder Schizophrenia GAD PTSD Postnatal depression OCD Eating disorder Bereavement Normal sadness Drugs side effects ```
29
Pharmacological treatment options for depression?
Antidepressants - SSRI, TCAs ,MAOi ECT CBT Counselling
30
What factors affect choosing an antidepressant?
``` Pregnancy Patient Preference Previous Treatment experience Suicidality Past history of elevated mood Age and Physical Health ```
31
On average how much earlier do people with severe mental disorders die vs. gen population?
10-25 years | Understand contributing factors can also lead to premature death -e.g. Co-mobitdities
32
Generally whose is more likely to have mental health problems Men or Women?
Women (X2)
33
Define Personality
Innate and enduring characteristics characteristics of an individual which shapes their attitudes, thoughts and behaviours in response to situations.
34
What is a personality disorder?
Enduring patterns of thinking and feeling about oneself and others that significantly and adversely affect how and individual functions in various aspects of life. Characteristics cause difficulties for themselves or relationships with others. Abnormalities must not be caused by any other condition. Out keeping with social & cultural norms.
35
What are the 3 classifications for personality disorders?
Cluster A - Odd/Eccentric Cluster B - Dramatic, Emotional & Erratic Cluster C - Fearful & Anxious MAD BAD SAD
36
What the CLUSTER A Personality disorders?
Paranoid Schizoid Schizotypical
37
What the CLUSTER B Personality disorders?
``` Histrionic Narcissistic Antisocial (dissocial) Emotionally Unstable Borderline Emotionally Unstable Impulsive ```
38
What the CLUSTER C Personality disorders?
Avoidant Dependent Anankastic (OCD)
39
Characteristics of Paranoid PD?
Suspicious of others - interprets motives as malevolent Sensitive Pervasive distrust Jealousy (Partners fidelity)
40
Characteristics of Schizoid PD?
Pattern of detachment from social relationships Excessive introspection & fantasy Wants nothing to do with social interaction
41
Characteristics of Schizotypical PD?
Strange/Odd behaviour Strange Appearance, belief & thinking Interpersonal discomfort NO PSYCHOTIC EPISODE
42
Characteristics of Antisocial PD?
Violates rights of others/ Callous lack of concern No respect for authority Aggression and Irritability
43
Characteristics of Histrionic PD?
``` Flamboyant Attention seeking Seductive Excessively emotional / Self-dramatisation Manipulating behaviour Egocentric ```
44
Characteristics of Narcissistic PD?
Grandiosity Lack of empathy Heighten importance of self Need for admiration
45
Characteristics of Borderline PD / EUPD?
Unstable self-image Unstable relationships Splitting views of individuals - All good or All Bad
46
Characteristics of Emotionally Unstable Impulsive PD?
Inability to control anger | Unpredictable affect and behaviour
47
Characteristics of Anxious/Avoidant PD?
Very timid & shy Low self-esteem Avoids social contact - Uncomfortable Afraid or rejection
48
Characteristics of Dependent PD?
Passive allow others to direct their lives Lacks self-confidence See themselves as hopeless or stupid Clingy
49
What is the management for personality disorders?
Pharmacological Intervention A & B - Antipsychotics C - Antidepressants Mood stabilisers - Li or Anticonvulsants to control affective instability or impulsivity Psychodynamic therapy DCT CBT Substance abuse treatment program referral
50
Which Personality Cluster has highest rate of suicide or violent deaths
Cluster B
51
Complications are personality disorders
Substance misuse Self-Harm and suicide Depressive disorder
52
Differentials Personality disorders?
``` Substance misuse Affective disorders Psychotic disorders Anxiety disorders (Phobia & Panic) Dementia ```
53
Characteristics of Anankastic (OCD) PD?
Perfectionist Preoccupied with trivial details Inflexible Feelings of excessive doubt or caution
54
Investigations for PD?
Clinical Interview Urine drug screen MRI/CT scan of brain Questionairres for differentials - PHQ-9, GAD-7, GAD2, SAPAS(Standardised Assessment of Personality Abbreviated Scale)
55
What are the main purposes for conducting a suicide risk assessment?
1. Establish Patients intent. 2. Assess the seriousness and perceived seriousness of attempt. 3. How the patient feel about the attempt
56
Suicide Risk Assessment? - What areas do you need to cover
1. Current Episode of self harm - Before Event, During Event, After Event 2. Previous Episodes of self-harm 4. Screen for Mental health conditions - Depression / Psychosis / Anorexia/ Alcohol Dependency 3. Past psychiatric history and remainder of normal history taking- PMH, DH FH, SH SH Needs to be focused on more!!
57
Questions MUST ask about self-cutting?
``` Location of cuts How many cuts? How deep? Feeling when they saw blood? Perceived outcome of cutting? Feelings at moment of cutting? ```
58
Questions MUST ask about OD?
``` Type of medication? How they got medication? How much medication was taken? What did you take with the medication? Perceived outcome of taking the medication? How long have you been planning taking medication? Action after taking medication? How they got to hospital? ```
59
Suicide Risk Assessment BEFORE Questions?
Trigger? Planned or impulsive? Any Final Acts? Preparative acts - Will, Note, Money transfers etc... Any precautious steps taken not to be discovered? Influenced by drugs or alcohol?
60
Suicide Risk Assessment DURING Questions?
``` Method? Alone? Location? Actions after self harming? Did they think self-harm would kill them? Thoughts at the time? ```
61
Suicide Risk Assessment AFTER Questions?
Did you call anyone? Currently feel suicidal? If you were to go home today, what would you do? Any preventative factors against future self harm? Willingness for treatment?
62
What areas of a SH need to be addressed?
``` Living situation Relationships & Dependants Occupation Drug & Alcohol Use ADLs ```
63
Possible Psychosis, Suicide Risk Assessment What questions should you ask?
Are thoughts to harm ever not your own? Do you feel that there are voices telling you to self-harm that others cannot hear? How do they know these voices are not their own worries?
64
Define Suicide?
Act of intentionally killing oneself with the primary aim of dying
65
Define attempted suicide?
Act of intentionally killing oneself with the primary aim of dying, but failing to do so.
66
What is Parasuicide?
Act that looks like suicide but doesn’t result in death as a cry for help, attention, revenge or expression of despair.
67
What is Deliberate Self Harm?
Deliberate Self Harm (DSH) Act of intentionally injuring oneself not intended to cause death but to gain relief from psychological stress / pain.
68
What are sociodenographic risk factors for suicide?
Gender - M>F Age - 15 -44 Marital status - Single, divorced, widowed Unemployed Occupations- Farmers, doctors, Vets, pharmacists Socioeconomic status- G4 & 5 Poor/no level of social support - elderly, prisoners, refugees Personal reasons - Abuse as a child, access to means Sense of hopelessness/feeling of entrapment
69
What are the clinical factors for suicide?
Hx of DSH Mental disorder Physical illness (Chronic) / significant pain. FH of DSH
70
What are the 5 Main categories for mental illness?
``` Mood Disorders Psychosis and Schizophrenia Anxiety Disorders Eating Disorders Dementia ```
71
How can all mood disorders be divided?
Primary Mood disorders | Secondary Mood disorders (Organic)
72
What are the primary mood disorder categories?
Unipolar Depressive Disorder - Mild, Moderate, Severe, Psychotic Dysthymia Bipolar Bipolar Affective Disorder - B1 & B2 Cyclothymia
73
Define Primary mood disorder?
A mood disorder that doesn't result from another medical or psychiatric condition
74
Define secondary mood disorder?
Mood disorder that results from another medical or psychiatric condition - e.g. anaemia, hypothyroidism, substance missuse
75
What criteria must be met for a mood disorder to be classed as bipolar?
MUST HAVE HAD 1 OR MORE EPISODES OF MANIA OR HYPOMANIA
76
What is recurrent depressive disorder?
A patient that has had more than one episode of depressive disorder. Current episode - classified for a single episode
77
Define Bipolar 1?
Episodes of major depression and mania - Full blown mania lasting at least 7 days - Major depression at least 2 weeks - Symptoms of mania severe enough that hospitalisation is required
78
Define Biopolar 2?
Episodes of major depression and hypomania -No full blown manic or mixed episodes (No history)
79
Define Cyclothymia?
Recurrent episodes of mild elation and mild depressive symptoms that aren't sufficiently severe or prolonged to meet criteria for BPD Hypomanic and depressive symptoms don't meet B2 Criteria "Mild chronic bipolar affective disorder. "
80
Aetiology behind mood disorders?
Genetics Change in neurorecptors functions Neurochemical imbalances - Depletion of nAd, serotonin, dopamine Organic causes Environmental factors - Life events Neurological abnormalities - loss of volume in frontal and temporal lobes
81
What effect does cocaine and amphetamines have?
Increases the levels of monoamines in synaptic cleft + elevates mood.
82
What are organic causes?
Neurological, Endocrine, Metabolic, Neoplastic, Drugs
83
What blood level is lithium toxicity considered
>1.5 mmol/L
84
Name a fast acing sedative used in highly agitated and difficult to manage individuals
Lorazepam
85
Name some anticonvulsants
Lamotrigine, Carbamazepine, Valproate
86
Define psychomotor retardation
Slowing down of thought Reduction of physical movements in an individual Can be visible and be observed in speech and affect.
87
What are the 5 principles of the mental capacity act
1. ASSUME a person has CAPACITY unless proved otherwise. 2. Don't treat people as incapable of making unless ALL PRACTICABLE STEPS have been been taken to help make a decision 3. Don't treat a person as unable to make a decision just because they seem to make an UNWISE DECISION 4. Always take decisions in THE BEST INTERESTS of a person who lacks capacity 5. Before making a decision consider if the act can be acheived in a LEAST RESTRICTIVE way of a persons right and freedom of action
88
What requirements must a person with capacity meet to make a decision?
1. UNDERSTAND information RELEVANT to the decision 2. RETAIN information for a sufficient period to make decisions. 3. Use & WEIGH UP information as part of a process of making the decision 4. COMMUNICATE their decision
89
What are the two types of sensory deceptions
Hallucinations | Illusions
90
What are the 4 disorders of thought?
Stream of thought Possession of thought Content of thought Form of thought
91
Define Anxiety
State of psychological and physical symptoms brought about by a sense of apprehension at a perceived threat.
92
Causes of anxiety disorders
Genetic factors Neurochemical abnormalities - GABA inbalance Environmental factors - Stressful events
93
Describe the steps in the cognitive behaviour model for panic disorders
1. Initial trigger + Risk factors leads to 2. Fearful thoughts 3. Emotions of fear and anxiety 4. Body fight and flight system kicks in 5. Symptoms of anxiety occur 4a. Behavioural changes are taken to avoid panic.
94
What are the treatment options for panic disorders
TCAs, SSRI, CBT, Benzodiazepines.
95
Describe the characteristics of a panic attack Describe the features on cognition, behaviour and anxiety occurrence for panic disorders
Rapid onset of severe anxiety, lasts 20-30 minutes. Associated cognitions- Fear of symptoms Anxiety occurrence - Episodic (Occur recurrently and unexpectedly) Associated behaviour- Escape
96
What lasting complications can arise from panic attacks
Secondary Agoraphobia -Panic attack makes person avoidant of leaving the house to reduce risk of having a panic attack
97
What is generalised anxiety disorder
Persistent and excessive worry about a number of activities or events. (>- 6M, Most days) Uncontrollable and irrational worry Anxiety and worry are associated with symptoms (3+) It is neither situational or episodic. (Phobia, Panic Disorder)
98
What are the symptoms associated with GAD? (6)
``` Concentration difficulty Restlessness Irritability Muscle tension Sleep disturbance (Falling asleep, staying asleep) Being easily fatigued ```
99
What diagnostic tool is used for Generalised anxiety disorder?
GAD-7
100
Name First Rank Symptoms (Schneiders)?
Auditory hallucinations - Thought echo, 2nd Person, 3rd person, voices arguing or commenting. Thought Allienation (X3) -Thought Withdrawal, insertion, broadcasting Somatic passivity Delusional perception Made feelings, impulses or actions (volition, affect, impulse)
101
Define Delusional perception?
Attribution of a new meaning usually in sense of self reference to a normally perceived object Combines memory+ delusional significance e.g. person thinks he's from royal decscent because he remembers a spoon as boy that had a crown on it.
102
Define Passivity?
Belief that one's thoughts or actions are influenced or controlled by an external agent.
103
What is the DSM-5 Criteria for BRIEF PSYCHOTIC EPISODE?
At Least 1: Delusions, Hallucinations or disorganised speech Time period: >24H but LESS THAN 30 days n.b. - good consideration when considering a differential of delirium
104
Define Delirium
Neuropsychiatric syndrome A sudden state of severe confusion and rapid changes in brain function and mental abilities.
105
In what circumstances should Benzodiazepines be used?
Alcohol/benzo withdrawal suspected catatonia C/I to antipsychotics and extremely agitated NOTE- Can make delirium worse
106
Define Psychosis?
A symptom or feature of mental illness characterised by radical changes in personality, impaired functioning, and a distorted or nonexistent sense of objective reality. Person loses contact with reality. Loss of function Lack on insight
107
What are the main symptoms of psychosis?
Hallucinations Delusions Confused and disturbed thoughts
108
What are the investigations for psychosis?
Rule out organic causes - FBC, UE, Urine drug screen, LFTs, Kidney function, Glucose, Folate & Vitamin B Levels (12,1,3), TFTs, Blood culture ESR, ANA - (Autoimmune)
109
What are the treatments for psychosis?
Biological Psychological Social
110
Define Hallucination?
A false sensory perception experienced without external stimulus.
111
Types of hallucinations?
Auditory - False perceptions of sound Visual - False visual perceptions of sound Tactile - False perceptions of touch (Formication) Gustatory - False perceptions of taste Olfactory - False perceptions of smell
112
Mneumonic for TCA Side Effects
Can't see - Blurred vision Can't pee - Urinary retention Can't spit - Dry mouth Can't shit - Constipation
113
Risk Factors for interaction with perinatal psychiatry? Perinatal - During Pregnancy up to 1 year postpartum
``` Low socioeconomic status Lone Parent Teenage pregnancy Unwanted pregnancy Low social support Poor family relationships ```
114
Main conditions associated with perinatal psych?
``` Postnatum depression Baby Blues Postpartum (puerperal) psychosis Perinatal OCD Perinatal PTSD ```
115
What is Anorexia Nervosa? (AN)
Eating disorder chartered by restriction of caloric intake leading to: Low body weight Intense fear of gaining weight Body image disturbance
116
What is key distinction between Bulimia Nervosa vs. AN
BMI BN >21 AN<18.5 (15%+ below expected) BN - Normal/Overweight AN- Underweight
117
Treatment for AN?
1. Structured eating plan with oral nutrition 2. Psychotherapy - AN Family therapy 3. Fluid Repletion of any loss electrolytes-K, Ca2, Mg2+, Na, +- SSRI Depression (Fluoxetine) In extreme cases - NG feeding, oral feeding. Feeding as a treatment for MHA assessment Education on nutrition to challenge over-valued ideas.
118
Investigations for AN?
``` CBC UE LFTs - UP ALT, AST TFTs - Low T3 Urinalysis ECG ``` Possible additionals - Hormone levels (Test, estradiol), Bone density
119
What can cause Metabolic alkalosis & Hypokalemia results.
Vomiting
120
Why is early intervention important in AN?
Prevents long term psychiatric and physical complications of AN
121
What are the key signs and symptoms for AN?
``` Muscle loss Hypotension Bradycardia Orthostatic HTN Amenorrhea Lack of libido Halitosis Electrolytes - HypoNA, Mg, Po Fatigue/Low energy Dry scaly skin Brittle hair Peripheral neuropathy Infertility Constipation Anaemia, Leukopenia, Thrombocytopenia Brain atrophy - Ataxia, confusion Cardiac symptoms - Oedema (CHF) ```
122
Aetiology of AN?
``` Genetic/Hormonal -Abnormalities in signals that convey hunger & satiety Social/Environment -Peer groups -Popular culture/Social media -Thin societal beauty standard ```
123
Risk Factors for AN?
``` Young women Adolescence and puberty obsessive and perfectionist traits Exposure to western media Middle & upper socioeconomic status Athletes ```
124
What are the two types of AN?
Restricting - Person doesn't regularly engage in binge eating or purge behaviour No variability in diet Weight loss via dieting, exercise, fasting Binge-eating purging (Eating large amounts, then self inducing vomiting or purge) Binge/Purge - Person regularly engages in binge eating or purge behaviour
125
What is purging? Give examples
(Evacuating behaviour) Self inducing vomiting, misuse of laxatives, diuretics, diet pills
126
Examples of restricting behaviour seen in AN?
``` Refuse to eat infront of others Specific food rituals - v.small pieces, food order Purging Exercise Weight
127
Differentials for AN?
Loss of appetite - Secondary to drugs Depression/OCD GI Disorders (Crohns, UC, malabsorption syndrome) Brain Tumours
128
What is Bulimia Nervosa? (BN)
Eating disorder characterised by recurrent episode of binge eating, followed by binge compensatory behaviour.
129
What is binge eating?
Eating amount of food definitely larger than most people would eat X2 the normal amount of food ingested.
130
How long are binge-episodes typically?
At least ONCE weekly for 3 months
131
Clinically Signs & Symptoms for BN?
132
RF for Bulimia Nervosa?
``` Female gender Personality disorder FH of obesity Childhood Hx of obesity Exposure to media pressure History of sexual abuse ```
133
Treatment for BN?
CBT & Psychotherapy Nutritional and meal support SSRI -Fluoxetine / SNRI-Venlafaxine
134
Investigation for BN?
FBC UE - Hypokalemia, other electrolytes decreases LFTs Pregnancy test (Always be consider for change in symptoms) Urinalysis - (possible ketones / poor glycemic ctrl) Serum creatinine - UP
135
What are the SIGECAPS depression Symptoms?
``` Sleep Interest - Lack of interest (Anhedonia) Guilt Energy Concentration Appetite Psychomotor retardation Suicidal Ideation ``` Diurnal mood variation (Feel worst on waking and gradual improve)
136
Examples of psychotherapy?
``` CBT DBT Interpersonal Family therapy Mindfulness based therapy Cognitive analytical therapy ```
137
What factors can affect the prognosis of depression?
``` Psychotic symptoms Alcohol use Early onset Level of social support Age ```
138
Define Nihilistic delusions?
Delusions of 'nothingness' and refer to rotting death or decay. They are consistent (congruent) with depressed mood
139
What are some organic/physical causes of depression?
``` Hypothyroidism Cushing's syndrome Parathyroid disease Renal failure Folate deficiency Cerebral tumours Alcohol or drug misuse ```
140
Which antidepressant is relatively safe in overdose?
Mirtazapine
141
What are the different classifications of Schizophrenia? | 6 ICD-10
``` Paranoid schizophrenia Hebephrenic schizophrenia Catatonic schizophrenia Undifferentiated schizophrenia Residual schizophrenia Simple schizophrenia ```
142
Define Schizophrenia
Mental illness that affects how a person thinks, feels, and behaves. Functional Psychosis disorder Fragmentation of thinking Lifetime Risk - 1 in 100
143
What are positive symptoms?
Symptoms that tend to represent a change in behaviour or thought. Usually sudden with onset
144
What are Negative symptoms?
Negative symptoms usually involve a decline in normal functioning. Usually insidious
145
Name positive symptoms for schizophrenia?
``` Thought echo (hearing your own thoughts out loud)* Thought insertion or withdrawal* Thought broadcasting* 3rd person auditory hallucinations* Delusional perception * Passivity and somatic passivity* Odd behaviour/Chaotic behaviour Thought disorder Lack of insight ``` * Schneider’s First Rank symptoms [Thought Disorder]
146
Name negative symptoms for schizophrenia?
``` Blunted affect Apathy Social isolation Poverty of speech Poor self-care ```
147
Risk Factors for Schizophrenia?
``` Obstetric complications FH of schizophrenia Migrant status Cannabis use Childhood abuse Psychological stress Increased paternal age of birth (>55) ```
148
Define Avolition?
Loss of motivation
149
Define Alogia?
Poverty of speech - Struggling to give answers to brief questions.
150
Whats the most prevalent type of schizophrenia?
Paranoid Schizophrenia Characterised by paranoid delusions and auditory hallucinations.
151
What important to set out in the treatment for schizophrenia?
Care Programme Approach
152
What's involved in the care programme approach for schizophrenia?
4 Stages Assessing health and social needs Creating a care plan Appointing a key worker to be the first point of contact Reviewing treatment
153
Two classes of antipsychotics? Whats the difference? N.B- Always check lipids before starting antipsychotics
Typical Atypical Typical antipsychotic drugs act on the dopaminergic system, blocking the dopamine type 2 (D2) receptors. Atypical antipsychotics have lower affinity and occupancy for the dopaminergic receptors, and a high degree of occupancy of the serotoninergic receptors 5HT-2A Extrapyramidal (motor) S/E - Typical More More withdrawal symptoms - Atypical
154
What is required for a schizophrenia diagnosis? [ICD -10 > DSM 5)
1. At least 2 of: Hallucinations, delusions, disorganised speech, catatonic behaviour/ -ve symptoms occurring for 1 Month + and continuous problems over a 6M period. At least one +ve Symptom [DSM-5] 2. No other cause for psychosis such as drug intoxication or withdrawal, brain disease (including dementia/delirium/epilepsy), or extensive depressive or manic symptoms A first-rank symptom or persistent delusion present for at least one month [ICD-10]
155
Investigations to rule out organic causes of schizophrenia?
MSU to rule out UTI causing delirium Urine drug screen to rule out drug intoxication CT scan if an organic neurological cause is suspected HIV testing if applicable Syphilis serology if applicable Bloods including FBC, TFTs, U+Es, LFTs, CRP and a fasting glucose
156
Which neurotransmitters are involved in the neuroreceptor hypothesis of schizophrenia?
Dopamine - Excess causes overactivity in mesocorticolimbic system & causes +Ve symptoms Serotonin - Increased activity Glutamate - Decreased activity
157
1st Line Antipsychotic for acute psychotic episode (With schizophrenia)?
Risperidone/Olazanpine + IM Lorazapam - Extreme agitation, aggression/violence + Procyclidine (To reduce) extrapyramidal effects
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Differentials of Schizophrenia?
``` Schizoaffective disorder Substance induced-psychosis Dementia w/psychosis BAD w/Psychosis Hyperthyroidism Hyperparathyroidism Delusional disorder Brief psychotic disorder Poisoning - CO2, heavy metal ```
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Schizoaffective disorder?
Chronic mental illness characterised by the symptoms of schizophrenia & mood symptoms at the same time. Mood symptoms present for a great portion of psychotic disturbance =Schizophrenia (Psychosis) + Mood Disorder (Mood symptoms)
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What are the most common types of delusions? [Expand]
Delusions of persecution | Delusions of grandeur.
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Define Catatonia?
Stopping of voluntary movement or staying still in an unusual position (motor immobility) Wave flexibility - Able to stay in the same position for hours
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What are examples of traumatic events that could cause PTSD
``` War Physical Assault Sexual/physical abuse Rape Kidnapping Crashes - Car/Plane Natural disasters ```
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Who tends to be at higher risk of PTSD. Men/Women?
Women
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Benzodiazepines ACTION? INDICATIONS? Symptoms of withdrawal?
Enhance the inhibitory effect of GABA Increase the frequency of chloride channel opening Sedation, hypnotic, anxiolytics, anticonvulsant,muscle relaxant insomnia, irritability, anxiety, tremor, loss of appetite, tinnitus, perspiration, perceptual disturbances, seizures
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Lithium Monitoring Requirements?
Lithium levels should be performed weekly and after each dose change until concentrations are stable. 12 hours after the last dose (If acute) Lithium blood level should be checked every 3 months TFTs & Renal func should be checked every 6 months.
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Major side effect for ECT therapy?
Memory Loss (Retrograde)
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What are the downsides of clozapine treatment in schizophrenic patients?
Reduces seizure threshold, making seizures more likely ``` S/E hypersalivation agranulocytosis myocarditis / PE neutropaenia constipation Smoking cessation can cause a rise in clozapine blood levels ``` Last resort treatment - Once patient is resistant to other (2+) antipsychotics. FBC Moniotring prior to treatment & ECG
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Name Some Atypical antispsychotics?
``` Clozapine Olanzapine Quetiapine Risperidone Apiprazole - Best side effect profile (Good for high prolactin) ```
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Name some typical antispsychotics?
Haloperidol Chloropromzaine Zuclopentixol
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Lithium medication side effects?
``` Nausea/vomiting, diarrhoea fine tremor nephrotoxicity ECG: T wave flattening/inversion Weight gain Leucocytosis ```
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What is the name of the condition in which a patient believes that they are either dead or non-existent?
Cotard syndrome. Delusional disorder (Nihilistic delusion subtype)
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What type of medication should not be mixed with SSRIs?
Monoamine oxidase inhibitors- due to the risk of serotonin syndrome.
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Symptoms of serotonin syndrome?
``` Fever Confusion Seizures Renal and hepatic impairment Arrhythmia, Increased muscle tone Hypersecretion of sweat. ``` To avoid this, patients should be given a 14-day washout period between MAOIs and SSRIs.
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Give a timeline for presentation of Alcohol Withdrawal to DT?
Symptoms: 6-12 hours - tremor, sweating, tachycardia, anxiety Seizures: 36 hours Delirium tremens: 72 hours -coarse tremor, confusion, delusions, auditory and visual hallucinations, fever, tachycardia
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Define Agranulocytosis?
Lowering of WBC count. (Primarily Neurtrophils) Clozapine can cause this side effect.
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Name some SNRIs? MOA?
Duloxetine Venlafaxine Inhibiting the reuptake increases the concentrations of serotonin and noradrenaline in the synaptic cleft
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What are the score ranges for depression in PHQ-9 Questionnaire?
``` 0-4 no depression identified 5-9 mild depression 10-14 moderate depression 15-19 moderately severe depression 20-27 severe depression ``` MAX - 27
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Which SSRI should be avoided in pregnancy?
Paroxetine Increased risk of congenital malformations
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What actions might make you think an individual is at increased risk of completing suicide in the future?
``` Efforts to avoid discovery Planning suicide Leaving a written note Final acts - sorting out finances Violent methods for dying ```
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Clinical features of Anorexia Nervosa?
Reduced BMI Bradycardia Hypotension Enlarged salivary glands
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Physiological abnormalities of AN?
most things low G's and C's raised: GH, Gluc, Salivary glands, Cortisol, Cholesterol, Carotinaemia/Xanathaemia (Increased Beta-Carotene) ``` hypokalaemia Low sex hormones- FSH, LH, oestrogens and testosterone Raised cortisol and GH impaired glucose tolerance hypercholesterolaemia hypercarotinaemia low T3 ```
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Define Echolalia?
Repetition of someone’s speech. including the question that was asked.
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Define Neologism?
The formation of new words.
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Define Perseveration?
When ideas or words are repeated several times despite an attempt to change the topic.
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Define Tangentiality?
Wandering from a topic without returning to it.
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Define Circumstantiality?
Circumstantiality is the inability to answer a question without giving excessive, unnecessary detail. However, the person does eventually return the original point.
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What are factors suggesting diagnosis of depression over dementia?
short history, rapid onset biological symptoms e.g. weight loss, sleep disturbance patient worried about poor memory reluctant to take tests, disappointed with results mini-mental test score global memory loss (dementia characteristically causes recent memory loss)
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Side effects of antipsychotics?
Antimuscarinic: dry mouth, blurred vision, urinary Retention, constipation Sedation, weight gain Raised prolactin may result in galactorrhoea due to inhibition of the dopaminergic tuberoinfundibular pathway impaired glucose tolerance neuroleptic malignant syndrome: pyrexia, muscle stiffness reduced seizure threshold (greater with atypicals) prolonged QT interval (particularly haloperidol)
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What two conditions have an increased risk with use of antipsychotics in elderly individuals?
Stroke | VTE
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What Extrapyrdimal S/E can antipsychotics cause?
Parkinsonism acute dystonia: sustained muscle contraction (e.g. torticollis, oculogyric crisis) akathisia (severe restlessness) tardive dyskinesia (late onset of choreoathetoid movements, abnormal, involuntary, may occur in 40% of patients, may be irreversible, most common is chewing and pouting of jaw)
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How may Extrapyramidal S/E be managed?
procyclidine (anticholinergic drug)
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Why are SSRI advised against in Preganacy?
They may increase the chance of congential heart defects and malformations in children. Especially 1st Trimester use
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What risk condition do you need consider when prescribing citalopram?
Long QT Syndrome CI: Patients with pre-existing QT interval prolongation; or in combination with other medicines that prolong the QT interval
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Which SSRI is safer in patients who have had a myocardial infaction?
Sertraline
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Name some risk factors that may indicate a worse prognosis for schizophrenia?
``` Strong family history Gradual onset Low IQ Premorbid history of social withdrawal Lack of obvious precipitant ```
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What is flight of ideas?
Expression of rapidly shifting thoughts in an individual. e.g leaps from one topic to another but with some link between them. Feature of Mania
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Define Mania?
Persistently elevated mood state with psychotic symptoms. >7 Days severe functional impairment Psychotic symptoms -delusions of grandeur or auditory hallucinations
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What is the first line pharmacological treatment in patients with alcohol withdrawal?
Benzodiazepines: Chlordiazepoxide. Lorazepam may be preferable in patients with hepatic failure.
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# Define Pseudohallucinations? Who may present with this symptom?
False sensory perception in the absence of external stimuli when the affected is aware that they are hallucinating. Grievers Can be auditory and visual.
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What the 5 Stages of grief?
Denial, Anger, Bargaining, Depression, Acceptance
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Criteria for abnormal grief?
Prolonged grief lasting >6M to >12M
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What psychiatric symptom can occur as S/E of steroids?
Induced Psychosis ``` C – Cataracts U – Ulcers S – Striae, Skin thinning H – Hypertension, Hirsutism I – Immunosuppression, Infections N – Necrosis of femoral heads G – Glucose elevation P- Psychosis O – Osteoporosis, Obesity I – Impaired wound healing D – Depression/mood changes ``` [Glucocorticoid Excess]
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ICD-10 Criteria for OCD?
- Most days for >2 wks - Cause distress / interfere with functioning (usually by wasting time) + must have ALL the following features: FORD CAR ``` F = Failure to resist: if long term, resistance may be minimal O = Originate from person's mind RD = Repetitive + Distressing: at least 1 recognised as excessive / unreasonable CAR = CARrying out obsession / compulsion is not itself pleasurable ```
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Explain Section 2 of MHA(1983)?
Admission and Assessment section. 28 Days - Non renewable AMHP (Approved MH practitioner) + 2 Doctors (Section 12 Trained) Treatment t can be given against patient wishes.
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Explain Section 3 of MHA(1983)?
Treatment section 6 Months - Renewable Patients who have already been assessed under S2 or known service user. AMHP (Approved MH practitioner) + 2 Doctors (Section 12 Trained
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Explain Section 4 of MHA(1983)?
Emergency Admission Section 72 Hours Hold 1 Doctor + AMHP For assessment
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Explain Section5(2) of MHA(1983)?
A patient who is a voluntary patient in hospital can be legally detained by a doctor for 72 hours
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Explain Section5(4) of MHA(1983)?
Allows a nurse to detain a patient who is voluntarily in hospital for 6 hours
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Explain Section 135 & 136?
Section 135 a court order can be obtained to allow the police to break into a property to remove a person to a Place of Safety Section 136 Someone found in a public place who appears to have a mental disorder can be taken by the police to a Place of Safety 24 hours hold, whilst a Mental Health Act assessment is arranged Place of safety - Police station
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What Co-morbidities are patients with bipolar at increased of?
diabetes, cardiovascular disease and COPD
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What steps for Primary care referral should be made patients with Bipolar disorder exhibiting symptoms.
Hypomania -> Routine referral to CMHT Mania/Severe depression - Urgent CMHT referral.
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Management for Bipolar Disorder for acute episode
Psychotic Symptoms Olanzapine- Antipsychotic Lithium - Mood stabiliser / Valproate (Not in childbearing women) Depression Psychotherapy Fluoxetine - Antidepressent management In acute mania episode STOP ANTIDEPRESSANTS
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When is ECT Therapy indicated?
Severe depressiive illness Prolong or severe manic episode Catatonia Only for rapid and short term improvement of severe symptoms after other treatments have proved ineffective
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Management for Mild, Moderate & Severe Depression?
Always assess suicide risk and Identify any safeguarding issues, learning disabilities or cognitive impairments. Mild Discuss presenting problems Active monitoring and follow up (2 weeks) ``` Moderate Low intensity psychosocial intervention - IAPT (Improving access to psychological therapies) -Individual guided self help -Computer CBT -Group CBT SSRI/SNRIs ``` ``` Severe SSRI/SNRIs High intensity IAPT (Referral or Self referral) -Couples therapy -Behavioural activation -Interpersonal therapy ```
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Mania/Hypomania symptoms?
``` Persistent eleveated mood Irritability Pressured speech Flight of ideas poor attention insomnia loss of inhibitions increased appetite ```
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Name some types of psychotherapy?
``` Psychodynamic CBT -Individual -Interpersonal -Group based ``` Behavioural activation Couples therapy Counselling
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Mania VS Hypomania
FILLLLLL [Pass Med]
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What is cross-tapering medications?
Slowly reducing the drug dose of a current drug whilst slowly increasing the dose of a new drug.
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What is the SSRI of choice in children/teenagers
Fluoxetine
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Define Insomnia? [FILLLL]
Not enough or poor quality sleep Chronic: Acute:
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Define Hypersomnia?
Excessive daytime sleepiness
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Define Parasomnia?
Doing strange things in your sleep
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What is a delusional mood (Atmosphere) ? [PRIMARY DELUSION = TRUE DELUSION]
Person has belief something often terrible but of great importance is going to occur but don't know what it is. Mood state real interpretation delusional
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What is delusional perception (APOPHANOUS)?
Misinterpretation of the significance of something that's usually perceived. i.e - Traffic lights change from Red to Green == I AM GOD Perception real interpretation delusional
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What is a delusional memory (Retrospective delusions)?
Delusional interpretation of a normal memory. i.e - I was given a chocolate bar by my mum when I was younger == That's when I noticed a chip was implanted in me. Memory real interpretation delusional
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How can you tell between primary and secondary delusions?
Primary - Delusion is ultimately un-understandable. Not occurring due to another psychopatholocial cause - i.e mood disorders Secondary - Delusions are understandable when detailed psych history/exam is taken . Occurs due to other morbid psychological phenomena (mood disorder, perceptual disturbances)
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What is parasuicide?
An apparent attempt at suicide, in which the aim is not death.
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What type of drug is Mirtazapine? (3 Marks) Main S/E? (2 Marks)
Noradrenergic and specific serotonergic antidepressant. Inhibit the inhibitory presynaptic A2-receptors on both noradrenergic and serotonergic neurons, hence increasing NA and 5-HT signallin. It doesn't affect reuptake transporters. Fewer side effects and interactions than many other antidepressants and so is useful in older people with polypharmacy. S/E - Sedation and Increased appetite.
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PTSD Management
Trauma-focused cognitive behavioural therapy or EMDR trauma-focused cognitive behavioural therapy (CBT) watchful waiting may be used for mild symptoms lasting less than 4 weeks
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PTSD Clinical Features? 4 Pillars
Present Longer than 1M (DSM-5) Re-experiencing- Flashbacks, nightmares, repetitive and distressing images Avoidance - People, situations or circumstances resembling or associated with the event Hyperarousal - hypervigilance for threat, exaggerated startle response, sleep problems, irritability and difficulty concentrating Emotional numbing - lack of ability to experience feelings, feeling detached from other people. Anger issues/ substance misuse
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What organ can Lithium cause issues?
Thyroid - lithium inhibits thyroid hormone release is poorly understood. Cause Hypothyroidism Also cause hypercalcemia -bones, stones, abdominal groans, psychiatric overtones
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Whats more common in psychiatric disorders VISUAL OR AUDITORY HALLUCINATIONS?
Auditory Visual Hallucinations are more common in 'Organic Disorders'
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Schizophrenia Management?
Bio Antipsychotics - Risperdone (1st Line) Clozapine - Last resort AS (treatment resistance to 2 other tried antipsychotics) ``` Psyco CBT (Cope w/stress / voices) DBT Psychoeducation Family therapy ``` Social Housing/Finances Education/Employment Social activities
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Schizophrenia Management?
Bio Antipsychotics - Risperdone (1st Line) Clozapine - Last resort AS (treatment resistance to 2 other tried antipsychotics) ``` Psyco CBT (Cope w/stress / voices) DBT Psychoeducation Family therapy ``` Social Housing/Finances Education/Employment Social activities
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Necessary steps dealing with Aggressive/Violent patient?
Non-pharmacological de-escalation Offer oral lorazepam 1-2mg Lorazepam 1-2mg IM (Repeat every 30-60 min) Be-aware benzo induced respiratory depression - Treat w/ Flumazenil (GABA-A receptor antagonist)
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Risk factors for completed suicides ?
``` Male Young Divorced Mental illness Chronic illness Substance misuse ```
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Fregoli’s illusion (Delusional Disorder / Schizophrenia). Give an example?
You see a stranger and believe they are your brother
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Capgras syndrome (Delusional Disorder / Schizophrenia) Give an example?
You see your brother but believe it is a stranger impersonating him.
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Erotomania/De Clerambault’s (Delusional Disorder/ Schizophrenia) Give an example?
You believe someone (usually famous) is in love with you
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ICD-10 Classification of Mild, Moderate & Severe Depression?
Mild - 2/3 symptoms present - managing most activities Moderate - 4 or more symptoms present - Struggling to do anything but essential activities Severe (With or without psychotic symptoms) - Multiple and marked symptoms - Psychotic symptoms (if present) - All activities impossible
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How long should you continue depression treatment following recovery?
6-9 months following recovery due to high risk relapse
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Name Mood Stabilisers?
Lithium, Sodium Valproate, Carbamazepine
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Name some Tricyclic antidepressants?
Amitriptyline | Clomipramine
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Anxiety features?
[FILL] Nervousness, trembling, muscular tensions, sweating, lightheadedness, palpitations, dizziness, and epigastric discomfort
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Anxiety Management?
[FILL]
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OCD Mangement
[FILL]
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Name some benzodiazepine?
``` Lorazepam Diazepam (Valium) Zoldipem (Ambien) Librium (Chlorodiazepoxide) Heminevrin (Clomethiazole) Xanax (Alprozalam) ```
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If Clozapine does has been missed for 48 hours. What Action should be taken?
Re-titrate the clozapine dose again slowly.
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Non-Compliance with Antipsychotic medication? What's the alternative?
DEPOT Injection
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Symptoms of serotonin syndrome ? Management of serotonin syndrome?
Clinical Features Neuromuscular excitation - Hyperreflexia, myoclonus, rigidity) Autonomic nervous system excitation- Hyperthermia Altered mental state Management Supportive IV fluids Cyproheptadine Chloropromazine
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Who do you need to avoid given Z-Drugs (Zolpidem, Zopiclone)
Elderly. Increases falls risk
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Define Psychosomatic?
Real physical symptoms that arise from or are influenced by the mind and emotions rather than a specific organic cause Symptoms - Somatic symptoms - Sweating, Palpitations, Tachycardia, tremor, drowsiness etc.. e.g. of Psychosomatic disorder - Somitisation disorder
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What medications may be used in chronic insomnia alongside psychiatric symptoms?
Clomipramine (TCA) | Mirtazipine (Antipsychotic)
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Define Psychosis?
Abnormal condition of mind that results in difficulties in determining what is real and what’s not. Symptoms - Hallucinations - Delusions
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MAIN Contraindication of ECT? Side-Effects of ECT? (5 Marks)
Raised ICP ``` Headache Nausea Arrhythmia Retrograde memory loss Anterograde memory loss ```
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What form of psychotherapy is good for Bordline personality disorder?
DBT - Dialectical BT
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What is important to add if SSRI is being given to someone on NSAID Medication?
PPI Medication - Increased risk of GI bleeding in px taking SSRIs
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Common symptoms of panic attacks?
Sudden onset of palpitations Chest pain Choking sensations Dizziness Feelings of unreality (depersonalisation/derealisation) Secondary fear of dying, losing control or going made.
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Define Agoraphobia?
Excessive fear of being in a situation where a person can't freely escape or where help may not be available if something goes wrong. Leads to - Avoidance - Restriction in activities Can be enclosed spaces/Open spaces (crowds)
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What are some subtypes of depression?
Dysthymia - chronic but mild symptoms of depression that can be associated with physical illness or other [2 years duration ] Atypical depression - Depression that occurs with symptoms opposite to that expected. E.g. Patient increased sleep and increased appetite. Post-Partum dépression Psychotic depression
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What is Cotard's syndrome?
Mental disorder in which the affected person holds the delusional belief that they are dead, do not exist. V.Rare
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What are the 2 questions for quick screening of depression for further investigation (PHQ-2).
1. Felt low, depressed or hopeless | 2. Had little interest or pleasure in doing things
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NAME THE SYNDROME? Individual believes that a closely related person (Sibling, friend, partner) has been replaced by an exact double
Capgras Syndrome
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What's Othello Syndrome?
Individual has a delusional belief that their partner is cheating on them without any proof.
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NAME THE SYNDROME? When an individual has delusions that someone is deeply in love with them and can't live without them - Usually Famous people
De Clerambault (Ergotomania)
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Indications for ECT?
``` Catatonia Stupor Refractory to antidepressants High risk of suicide Psychotic features Food refusal, severe weight loss or dehydration Previous successful response to ECT ```
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Symptoms of Bulimia Nervosa (BN)?
``` Dental Erosion Abdo Pain Bloating Lethargy Heartburn Sore throat Halitosis ```
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Treatment for BN
CBT/interpersonal psychotherapy (IPT). Management in <18 BN- Family focused therapy – first line 18 sessions over six months encouraging regular eating and reducing bulimic behaviours CBT-ED – 18 sessions over six weeks if family therapy is ineffective. Management Adults Bulimia focused guided self-help programme Individual eating disorder focused CBT (CBT-ED) – 20 sessions over 20 weeks if self-help is ineffective.
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Incidence of: A - Postpartum Depression B - Postpartum Psychosis C - Postpartum Blues
A -10 - 15% B - 0.5% C -50 -75%
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What is the most common S/E of Clozapine? Possible Tx
Hypersalivation (Sialorrhoea) Hyoscine Others - Letheragy, Tachy, Hypotension, confusion
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Classic symptoms of Opioid OD?
Pinpoint pupils, Severe respiratory depression, Pulmonary oedema, Stupor, Pallor
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Symptoms of Opioid withdrawal?
``` Dilated Pupils Epiphora (eyes watering), Rhinorrhoea (nose running), Agitation Perspiration Piloerection (erection or bristling of hairs) Tachycardia Vomiting Shivering Yawning ```
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If Clozapine has been missed for 48H for whatever reason what actions should be taken?
Restart Clozapine at starting dose of 12.5mg. Titrate upwards accordingly.
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What are IQ Ranges for learning disability
<70 = Learning Disability <50 =Moderate <35= Severe disability
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Which SSRI is considered only in major depressive episodes?
Paroxitine
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Manic patient on an antidepressant and antipsychotic? FIRST STEP DEALING WITH TREATMENT?
Stop the antidepressant.
277
Define Pain Disorder?
Patient presenting with Intense, long-standing pain without somatic explanation. RESTRICTED TO PHYSICAL PAIN and not somatic (Somatisation disorder)
278
Define Somatisation?
Patient presenting with various physical complains that are not explained by a somatic process. Diffusie, odd mix of symptoms that can't be explained with a unifying diagnosis. [e.g pain, GI, sexual, neurological]
279
What are the Core features of ADHD?
1 - Inattention: Easily distracted, no listening, forgetful, easily losing things, unable to sustain attention for prolonged periods. 2 - Hyperactivity: Fidgety, restlessness, difficult to engage in quite activities 3 - Impulsiveness: interrupts others, can't wait, excessive talking, blurts out answers M>F
280
Define Projection?
Person assumes that an innocent, neutral character is responsible or is as guilty as the patient, for the patient's actions. e.g A cheater accusing an innocent person of doing the same thing.
281
Define Denial?
Not accepting a diagnosis or reality.
282
Define Fixation?
Person who obsesses over a thoughtcrimes, idea or object as a way of coping with a stressor.
283
Define Splitting?
Patient distinguishes between two groups of people. Those the patient loves and trusts versus those that the patient doesn't love or trust. People are considered good or bad and patient only cooperates with those people that the patient considers's good. Characteristic of borderline personality disorder.
284
Define Displacement?
Individual takes out their feelings on a neutral person. e.g. Patient displacing their feelings out on innocent people who aren not involved in the patient's situation.
285
What type of PTSD is EMDR not used?
Combat-related trauma. Trauma-focused CBT prioritised instead.
286
What are the 2 types of EUPD?
Borderline-type More difficulties with relationships, self-harming and feelings of emptiness. Impulsive-type More difficulties with impulsive behaviour and feelings of anger.
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Define Confabulation ?
Fabrication of imaginary experiences due to loss of memory. 'Confusing real events with those from their imagination' Common in patients with cognitive imparirement (e.g. dementia. Individuals are able to maintain superficial conversations through fabrication of events.
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What is shared delusion (folie a deux) ? | Best first step in management?
Shared delusional disorder where 2 co-dependent people develop a paired delusion. Separating the 2 individuals.
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What is VERY IMPORTANT part of the long-term risk management in reducing future self-harm of a patient?
Comprehensive psychosocial assessment of needs and risks (Care plan) - Identify needs of patient (Mental illness, social situation) - Form a crisis plan
290
# Define the phobias? 1. Acrophobia 2. Algophobia 3. Gamophobia 4. Agoraphobia
1. Fear of heights 2. Fear of pain 3. Fear of getting married 4. Fear of being out in public
291
When Switching SSRIs. What actions should you take?
Reducing current medication gradually over two weeks STOP - WASHOUT Period/Abstinence (4-7 days) Start new SSRI
292
Define Mood Disorder?
Set of psychological disorders where emotional state is distorted or inconsistent. Interfere with ability to function normally.
293
What class of drugs is used in the treatment of acute dystonia?
Anticholinergics
294
Which antipsychotics tend to cause EPSE?
Typical AntiPsychotics | e.g. haloperidol
295
If someone has tardive dyskinesia as a result of an antipsychotic (atypical) WHAT SHOULD BE DONE IMMEDIATELY?
Stop typical antipsychotic and switch to atypical one. e.g. Haloperidol to Olanzipine
296
Adjustment Disorder vs Major depressive disorder | Main distinction?
Experiencing symptoms of depression > 6 Months
297
What is Psychotherapy?
Form of counselling which employs various techniques to induce behavioural changes that will stay with the patient in the long term.
298
What does CBT involved?
Talking therapy exploring patient’s understanding, concepts and reactions towards a certain problem, gradually building behavioural changes to challenge the concepts and manage the problem.
299
What is imprinting?
Phase sensitive learning that is rapid and apparently independent of the consequences of behaviour. Learning occurring at a particular age or stage
300
What is classical conditioning?
Learning process that occurs through associations between an environmental stimulus and naturally occurring stimulus.