Neuro Flashcards
Key Points - Subdural Haematoma?
Cause: Rupture of bridging following a blunt trauma or fall
Shape: Crescent shape
Presentation: Initially asymptomatic, as haematoma grown, px develops a slow progressive headache with altered mental status
Mainly affects elderly patients
SUBway under the BRIDGE
Why are elderly patients are most increased risk of Subdural haematoma
Atrophy of the brain is more common.
More space for bridging veins to rupture.
Key Points - Epidural Haematoma?
Cause: Fracture of temporal bone, leads to rupture of the middle meningeal artery.
Shape: Convex Lens (Elipse)
Blood does not cross the suture line
Px experience Lucid Intervals & CN 3 Palsy
Key features of CN3 Palsy
Ptsois
Dilation
Down and Out movement of the eyes
Intraparenchymal Haemorrhage
Unilateral flailing of extremities
2nd most common cause of stroke after ischemia
Basal ganglia, internal capsule, thalamus, pons & cerebellum
HTN most common cause
Microaneurysms of perforating arteries ( Charcot-Bouchard)
Breakdown Stroke Classification Types
- Ischaemic
a -Thrombotic
b- embolic
c - Hypotensive
d - Hypertensive - TIA
- Haemorrhagic
-Subarachnoid
-Intraparenchymal - Haematoma
-Extradural(Epidural)
-Subdural
Subarachnoid Haemorrhage
Cause: Rupture of berry aneurysm
Signs: Worst headache of life / Thunderclap
Neck stiffness similar to meningitis
What would you expect from LP of someone who had a Subarachnoid Haemorrage
Bloody/Xanthocromic CSF
Key Points - TIA?
(Transient Ischaemic Attack)
Transient neurologic dysfunction due to a vascular cause, typically lasting less than an hour.
Caused by ischaemia (focal brain, spinal cord or retina) WITHOUT acute infarction
Symptoms usually lasts for minutes.
3 Types
1. Atherosclerotic (>70% Occlusion - Increased risk (Symptoms lasts for minutes)
2. Embolic (symptoms lasts for hours)
3. Lacunar
What RFs are most at risk for berry aneurysms
SHAME
Smoking
HTN
Acute polycystic kidney disease
Marfans syndrome
Ehlers-Danlos syndrome
Ddx for stroke
Post-ictal state (Todd’s paralysis)
Migraine headache aura
Vertigo/Meniere’s disease
MS
Brain tumour
Cerebral infection
Conversion disorder/Malingering
Whats the gold standard diagnostic investigation for a stroke
Non-contrast CT of head
(Provided the px is stable)
Differentiate between ischaemic or haemorrhagic stroke
Most accurate imaging for a stroke ?
Diffusion-weighted MRI (Takes too long in emergency)
Most common occluded artery causing stroke
MCA
Ddx of collapse?
Neurological -Generalised seizure epilepsy , TIA/stroke, vasovagal syncope, Parkinsons, Situational syncope (Cough, micturition), Raised ICP, Intracranial Haemorrhages, Neuropathy (MS)
Cardiovascular - Aortic stenosis, Postural HTN, Arrythmias, carotid sinus hypersensitivity, Subclavian steal syndrome, vertebrobasillar insufficiency, structural (cardiomyopathy)
Other causes - Diabetes/Hypoglycaemia, Drug OD/Toxicity, Alcohol, Falls Injury, Ruptured AAA, ectopic pregnancy, delirium, Sepsis
Groupings - Epilepsy, Syncope & Non-epileptic attacks
Define Syncope
Abrupt and transient LOC
Leads loss of postural tone
As result of fall in cerebral perfusion
What important areas should you consider when FOLLOWING a COLLAPSE?
[Big 6]
Eye witness account
Triggers
Prodrome
Description of collapse
Recovery
PMH/Personal Hx
What Neurological Disorders do you need to consider stopping driving/Informing the DVLA
Epilepsy/Seizures
Chronic neuro disoders - MS, MND, Narcolepsy
Brain tumour/pituitary tumour
(Complete PK1 form with DVLA)
It is the patient’s responsibility to notify the DVLA in the case of any seizure.
Driving guidelines for epilepsy/seizures?
First unprovoked/isolated seizure: 6M off if there are no relevant structural abnormalities on brain imaging and no definite epileptiform activity on EEG. 12M off if otherwise
Patients with established epilepsy or those with multiple unprovoked seizures:
May qualify for a driving licence if they have been free from any seizure for 12 months
No seizures for 5 years (with medication if necessary) a ’til 70 licence is usually restored
Withdrawal of epilepsy medication: should not drive whilst anti-epilepsy medication is being withdrawn and for 6 months after the last dose
Explain Driving guidelines for syncope?
Simple faint: no restriction
Single episode, explained and treated: 4 weeks off
Single episode, unexplained: 6 months off
Two or more episodes: 12 months off
Define Parkinsons Disease?
Chronic progressive neurodegenerative disorder characterised by motor symptoms of:
RESTING TREMOR
RIGIDITY
BRADYKINESIA
POSTURAL INSTABILITY
Onset of Parkinson’s?
Gradual
Characteristics of Migraine?
Recurrent, severe headache which is usually unilateral and throbbing in nature
May be be associated with aura, nausea and photosensitivity
Aggravated by, or causes avoidance of, routine activities of daily living. Patients often describe ‘going to bed’.
In women may be associated with menstruation
Characteristics of Tension Headache?
Recurrent, non-disabling, bilateral headache, often described as a ‘tight-band’
Not aggravated by routine activities of daily living