Psychiatry Flashcards
1
Q
What are pharmacokinetics of lithium
A
Rapidly absorbed in gi tract Not affected by food Peak serum levels in 1-2h Not protein bound Distributed in total body water Brain level peak in 2h Not metabolised Excreted almost totally in kidneys Half life depends on renal fn - young healthy : 24h
2
Q
Contraindications to lithium
A
Renal impairment Last t pregnancy Cardiac disease sig Dehydration Sodium depletion
