Psychiatry Flashcards

1
Q

Alogia

A

impoverished speech

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2
Q

Avolition

A

lack of desire drive or motivation to pursue meaningful goal

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3
Q

Avnhendonia

A

inaility to experience pleasure from normally pleasurable life events

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4
Q

Negative schizophrenia symptoms

A
  • memory and concentration
  • unusual behaviour
  • impaired communication
  • social withdrawal
  • decrease interest w/ daily activity
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5
Q

types of schizophrenia

A
Paranoid schiz
Hebephrenic schiz
catatonic schiz
undifferentiated schiz
post schiz depressiion
residual schiz
simple schiz
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6
Q

Schneider 1st rank symptoms

A

auditory hallucination
somatic passivity
delusion of passivity
delusion of perception

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7
Q

Schneider 2nd rank symptoms

A

2nd hallucionation
2nd delusions
visual tactile olfacory and gestatory hallucination
perplexity (inabilit to deal/ understand something)
emotional blunting

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8
Q

type 1 schizophenia

A
  • ACUTE
  • POSITIVE symptoms
  • functioned well before the symptoms
  • DUE TO: dopamine transmission problem
  • no neuro signs
  • good cognition
  • response well to antipyschiotics
    good prognosis
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9
Q

type 2 schizophrenia

A
  • CHRONIC
  • NEGATIVE symptoms
  • hx of poor social and education prior to it
  • DUE TO: structural brain abnormalities (CT - Dx)
  • neuro signs
  • impairment of cognition
  • response poor to antipyschiotics
  • poor prognosis
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10
Q

dopmine abnormalities in schiz

A

INCREASE dopamine release in mesolimbic stratum during lines
- correlates to positive symp and good prognosis

DECREASE in mesocortical system
- correlates with defective cognition

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11
Q

DDX of negative schiz symptoms

A

Depression
effects of neuroleptic meds
environmental under stimulation
physical illness (endocrine/ alzeihmers)
substance misuse
Schizoid or schizotypical personality disorder
autism / asperfer’s syndrome

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12
Q

Ambivalence

A

simutaneous contradictory thinking (angle and devil)

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13
Q

bleuler - four As of schizophrenia

A

Ambivalence
Autism (internal simuli)
inappropiate affect
loosening of association

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14
Q

epidemiology of schiz by sex and age

A

Males = 22 years
feamles = 26
MALES > female

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15
Q

Susceptibility genes and chromosomal abnormalities

A

Genes

  • DAOA - dopamine amino acid oxidase activator
  • dysbindin
  • neuroregulin
  • zinc finger protein 804A

Chromosomes

  • DISC1 - disrupted in schizophrenia 1
  • microdelition of chrom 22q11 (vela-cranial facial syndrome)
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16
Q

what season is schiz more common

A

babies born in spring and winter
NH: january - April
SH: Julyl - september

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17
Q

serotonin level in schizophrenia

A

INCREEASED

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18
Q

left handedness

A

increase risk of SCHIZOPHRENIA

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19
Q

why does cannibis increase schizophrenia

A

COMT gene moderates the influence of cannibis use on developing psychosis

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20
Q

brain abnormalities in schizophrenia

A

Ventricles larger >brain tissue
GREY matter loss > white
TEMPORAL lobe - esp. medial temporal lobe

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21
Q

why are males at greater risk of schizophrnia

A
Males: 
- increase obstetric problems 
- worse premorbid adjustment 
- more structural brian abnormalities 
negaitive sympto 
- worse prognosis
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22
Q

risk of suicide in schizophrenic patients

A

2%

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23
Q

schizohrenia is ass .w/

A

Smoking

Bipolar disease

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24
Q

schizotypical disorder

A

eccentric behaviour and anomalies of thinking and affect which resemble those seen in schizophrenia

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25
Q

schizoaffective disorder

A

episiodic disorger in which both affective and schizophrenic symptoms are prominent within the same episode of the illness preferably spontaneously but at least within a few days of each other

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26
Q

schizoaffective types with best and worse prognosis

A

best - schizoaffective type w. mania

worse - schizoaffective type w/ depression

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27
Q

ICD10 criteria - how long for symptoms

A

1 month or more

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28
Q
what is the least likely to be a DDX of negative symptoms of schizophrenia 
A - cannibis excess 
2. enviromental overstimulation 
3. Alzehimers disease 
4. Depression 
4. Aspergers syndrome
A
  1. enviromental overstimulation
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29
Q

the prevalence of schizophrenia

A

1%

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30
Q

tx of tardive dyskinesia

A
  1. stop anticholinergic and decrease antipsychotic dose

CHANGE to CLozapine

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31
Q

Tx for dystonia

A

Anticholinergics

- Procyclidine and biperiden

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32
Q

parkinsonism / psurdoparkinsonism tx

A

dose reduction

change to atypical

Anticholinergics
- Procyclidine and biperiden

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33
Q

akathisia treatment

A

decrease dose
switch to atypical
NO effect with Anticholinergics

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34
Q

response to clozapine in resistant tx schizophrenia

A

30-60%

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35
Q

indications for clozapine

A
treatment resistant schiz
tardive dyskinesia 
pyschosis in PArkinson
Huntington disease
resistent mania
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36
Q

Capgras syndrome

A

illusion of doubles - thinks they are placed by an exact double
- FAMALES >males

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37
Q

Fregoli syndrome

A

believer person/ object changes their identity and follows patient

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38
Q

Intermetamorphosis

A

belief that a person swaps identity BUT same apperance

39
Q

syndrome of sugestive double

A

Doopelgnager or double of himself carrying out independent task

40
Q

Dilusion misidentity syndrome names 4

A

Capgras syndrome
Fregoli syndrome
Intermetamorphosis
Syndrome of subjective double

41
Q

lycanthropy

A

a man who believes he is transferred into an animal

42
Q

Cotard syndrome

A

nihilistic delusion in which the person holds the delusion that they are DEAD, do not exist , are putrefying or lost blood and internal organs

43
Q

Folie a deux

A

delusion believe transferred from one sister to another

44
Q

Ekbom syndrome

A

delusion parasitosis . delusion of infestation

45
Q

Erotomania

A

the person believes someone high social or professional status is in love with them

46
Q

Morbid jealously

A

believes that there partner is or will be unfaithful

47
Q

Othello syndrome

A

MORBID jealousy

more common in MEN

48
Q

Couvade syndrome

A

non psychotic syndrome
- experiencing symptoms resmbling pregnnacy 9minor weight gain, monitoring nausea, abdo swelling) in MALE when female is pregnate

49
Q

Charles bonnnet syndrome

A

non psychotic syndrome
core fearues occurrence of well formed vivid and elaborate visual hallucination in a newly sighted person - ARMD , glaucoma or cataracts

GOES away in 18 months once brain adapts to lost of vision

50
Q

Ganser syndrome

A

giving approximate answers “five legs on table”
clouding cousiouness
true hallucinations or peudohalucination
Conversion symptoms

MALE , aka prison psychosis, resolves

51
Q

Diogenes syndrome

A

aka senile sqalor syndrome
EXTREME slef neglet
hoarding of rubbish or objects

52
Q

indication ECT

A
severe depression 
catatonia 
tx resistent mania 
postnatal psycosis 
NMS
intractable seizure disorder
53
Q

Contraindications to ECT

A
  • NO ABSOLUTE CONTRAINDICATIONS
Relative contraindications 
- Post MI in last 3 months 
Cardiac arrythmia 
INCREASe ICP 
Intercranial heamorrage 
brain/ vascular anneyursm 
brain tumour 
retinal detachment 
phaochromocytoma
high anesthetic risk
54
Q

Things that increase seizure threshold

A
MALES 
OLDER AGE 
Cilateral 
POOR scalp contact with electrodes 
Low oxygen saturation in blood 
Baldness , thickness in the bones, dehydration,
55
Q

Things that decrease seizure threshold

A
Younger 
fEmales 
Unilateral 
good scalp contact 
low CO2 in blood 
caffine and hyperventilation
56
Q

Drugs that increase ECT threshold

A
BA BMP 
- barbituates 
- anticonvulsants 
Benzodiazepam 
Methohexitone dose - > 1.2mg/kg 
Profolol
57
Q

Drugs that decrease ECT threshold

A
TALA 
- theophyline 
antidepressants 
lithium 
antipsychotics
58
Q

Bilateral placement of ECT probes

A

From external ear to angle of the eye - 4cm perpendicular tot that line

59
Q

Lanster position for ECT

A

frontotemporal position and vertically to the vertex

60
Q

Unilateral electrode placement - right UL (want to put it on non dominant hemisphere

A

b/w frontotempral region and the mastoid

61
Q

Mental Health Act - form 1

A

spouse or family

62
Q

Mental Health Act - form 2

A

Authorized officer (designated officer of HSE

63
Q

Mental Health Act - form 3

A

Gardai

64
Q

Mental Health Act - form 4

A

Stranger

65
Q

Mental Health Act - form 5

A
GP , in 24 hours, expiries 1 week 
GP CANNOT BE 
- spouse 
Gardai 
- money value 
- work in the centre in which they are being detained
66
Q

Who cannot fill out STEP 1 of Mental Health Act

A
67
Q

How long do you have for step 1

A

48 hours

68
Q

Step 3 - what form

A

Form 6 - by consultant psychiatrist - within 24 hours

Expiry 21 days

69
Q

Form 7

A

renewal order

1st renal

70
Q

form 14

A

discharge from approved centre - when the patient no longer suffers from mental illness

71
Q

comments of mental health tribunal

A

chairperson
consultant psychiatrist
3rd person - not a registered medical practitioner - usually a lay person

72
Q

Age of anorexia va. bulimia

A

anoreexia - 16-17 (female), 12 (male)

Bulemia - adolescent 20 years old

73
Q

criteria for admission

A
Medical 
- BMI 5 years 
co morbid with impulsive type 
intolerable family 
social situation 
personality disorder
74
Q

poor prognosis of anorexia

A
male 
chronicity for 6 or more years 
bulimic behaviour 
excessive weight loss 
premorbid heavy weight 
personality disorder
75
Q

obsetiy - leptin and grelin

A

increase leptin - due to increase fat mass

decrease grelin = slows body ability to burn fat

76
Q

early menarche is a risk factor for

A

anorexia narvosa

77
Q

least likely sign of anorexia nervosa

A

gastric contrsictors

78
Q

kleine levin syndrome

A

hypersomnea, hyperphagia and hypersexuality

79
Q

kluver bucy syndrome

A

hyperorality (objects in moth9 , hyperphagia, hyperseculatiy

80
Q

risk factor for baby blues

A

BIOLOGICAL

  • postpartum decrease in level of estrogen, progesterone and prolactin
  • premenstrual tension
  • primigravida status
  • increase degradation of tryptophan to kyneurenine (often occurring after the immunity

PSYCHSOCIAL (SASP)
- poor relation with partner
Physical and emotional stress of birthing
awareness and stress about increase responsibility
fatigue and sleep deprivation

81
Q

biological factors of postnatal drepression

A
older age 
severe baby blues 
past history of depresson during pregnancy or postpartum 
fam history of depression 
sensative to hormonal milieu
82
Q

physiological rf for postnatal depression

A
single mom 
marital instability 
adverse life event 
ambivalence towards pregnancy 
bonding difficulties 
sleep disturbances in LATE pregnancy
83
Q

symptoms of postnatal psychosis

A
RRIID 
Restless 
refusal for food 
irritablity 
insomnia 
depression
84
Q

risk factor for postnatal psychosis – biological

A
Dx BPD (25-50%) , schizophrenia, 
fam history of major psychiatry disorder 
decreae in P E C 
postnatal thryoiditis 
Primigravid status 
older age 
c-section 
HIGH SES 
HX POSTNATAL PSYCHOSIS - 74$
85
Q

pyschosocial RF postnatal psychosis

A

perinatal death of the baby
lack of social supper
psychodynamic factors - motherhood conflict, unwanted , trapped unhappy relationship

86
Q

risk of developing non puerperal BPA after having postnatal psychosis

A

20%

87
Q

risk of developing another pschosis episode having postnatal psychosis

A

57%

88
Q

sings of poor prognosis for post natal psychosis

A

family historyy physicatric disorder
schizophrenia
neurotic personality
presence of serve marital problems

89
Q

which antipsychotic is represented during pregnancy

A

trifluroperazine
ALSO:
- chlorpromazine, haloperiodol, olanzapine and clozapine

90
Q

high or low SES is a risk factor for postpartum depression

A

HIGH

91
Q

antipsychotic safe in breastfeeding

A

Olanzapine

92
Q

Antidepressant safe in breastfeeding

A

paroxetine and reboxetine

93
Q

antidepressant safe in pregnancy

A

fluoxetine
amitryptyline
imipramine
fluoxetine

94
Q

sedatives in pregnancy

A

chlorpromazine and amitriptyline