Psychiatry Flashcards
Paracetamol overdose <1 hour + dose <150mg/kg - managament?
activated charcoal
Paracetamol staggered overdose or ingestion >15 hours ago - management?
Start N-acetylcysteine immediately
When do you consider a liver transplant for paracetamol overdose?
Arterial pH < 7.3, 24 hours after ingestion
OR
All of the following:
prothrombin time > 100 seconds
creatinine > 300 µmol/l
grade III or IV encephalopathy
Patients who present 8-24 hours after ingestion of an acute overdose of more than 150 mg/kg of paracetamol - management?
N-acetylcysteine
patients who present > 24 hours with paracetamol overdose if they are clearly jaundiced or have hepatic tenderness + high ALT - management?
N-acetylcysteine
Difference between type I and type II bipolar disorder?
Type I - mania and depression
Type II - hypomania and depression
Severe lithium toxicity management?
Haemodialysis
Criteria for anorexia nervosa?
DSM 5
Management of anorexia nervosa in young people?
‘anorexia focused family therapy - 1st line
CBT - 2nd line
Management of anorexia nervosa in adults?
one of:
- individual eating-disorder-focused cognitive behavioural therapy (CBT-ED)
- Maudsley Anorexia Nervosa Treatment for Adults (MANTRA)
- specialist supportive clinical management (SSCM).
Clinical features of anorexia nervosa?
- reduced body mass index
- bradycardia
- hypotension
- enlarged salivary glands
Physiological signs of anorexia nervosa?
- hypokalaemia
- low FSH, LH, oestrogens and testosterone
- raised cortisol and growth hormone
- impaired glucose tolerance
- hypercholesterolaemia
- hypercarotinaemia
- low T3
Criteria for bulimia nervosa?
DSM 5
- recurrent binge eating
- lack of control when eating
- compensatory behaviour - laxatives, vomiting
- at least once a week for 3 months.
Management of bulimia nervosa in adults?
bulimia-nervosa-focused guided self-help - 1st line
Individual eating-disorder-focused cognitive behavioural therapy (CBT-ED) - 2nd line
Management of bulimia nervosa in children?
bulimia-nervosa-focused family therapy
Pharmacological option for bulimia nervosa?
Fluoxetine
Difference between bipolar type 1 and type 2?
Type 1 - mania and depression
type 2 - hypomania and depression
How do you differentiate mania from hypomania?
psychotic symptoms (e.g.delusions of grandeur or auditory hallucinations)
Management of bipolar disorder?
Lithium - mood stabiliser (valproate is an alternative)
mania - antipsychotics e.g. olanzapine or haloperidol
depression - talking therapies, fluoxetine
Acute stress disorder vs PTSD time frame?
first 4 weeks = acute stress
>4 weeks = PTSD