Psychiatry Flashcards

1
Q

what is the definition of psychosis?

A

an individual is experiencing a reality different to everyone else (the individual does not realise they are psychotic)

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2
Q

name some symptoms of psychosis.

A
  • hallucinations
  • delusions
  • formal thought disorder
  • disorders of one self
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3
Q

what is a hallucinations?

A

the perception of an object in the absence of an external stimulus (in clear consciousness) that others cannot percieve

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4
Q

what type of hallucination is most common in psychosis?

A

auditory hallucination

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5
Q

what can olfactory halucination indicate?

A

frontal lobe pathology

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6
Q

what is pseudohallucination ?

A

‘hearing voice in my head’ - not psychosis!!

hallucinations are external, not internal

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7
Q

what is the likely diagnosis when someone is visually hallucinating?

A

delirium - usually a organic pathology

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8
Q

what is a delusion?

A

fixed, firmly held beleif that is false , that cannot be reasoned away, that is held despite evidence to the contrary is out of keeping with the persons sociiocultural norms

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9
Q

what are teh types of delusions?

A

persecutory (believe ppl coming after you)
grandiose (think your’e amazing)
reference (about urself)
erotomanic (think someones in love with you)
hypochrondriacal (health anxiety)
nihilistic (feeling you are dead)
bizarre (absolute not possible )
control (think someone/thing is controlling you)

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10
Q

what is formal thought disorder?

A

a problem of speech (+ flow of thought) which means each sentence doesnt follow on from the next

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11
Q

what is disorders of the self?

A

when an individual can no longer distinguish between themself and the world
icnludes:
- thought insertion
- thought broadcasting
- passivity phenomena

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12
Q

what organic disorders must you rule out in psychosis?

A
  • delirium
  • dementia
  • infection
  • endocrine disorders
  • TLE
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13
Q

name the three types of functional psychosis?

A
  • schizophrenic (bizarre, persecutory, 3rd person)
  • manic (graniose, 2nd person)
  • depressive (guilt, poverty, nihilism, 2nd person)
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14
Q

what is shcizophrenia?

A

a disorder or group of disorders charatcerised by psychotic episodes (positive symptoms) and negative symptoms

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15
Q

symptoms seen in schizophrenia (5 a’s)

A

Autism
flat Affect (or incongruous)
Ambivalence
loosening of Associations (thought disordeR)
Amotivation or Apathy

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16
Q

name schneiders first rank symptoms for schizophrenia

A
  • hearing ones own thouhgts spoken alou d
  • hallucinatory voices in form of statment + reply, pt hears voices speaking about them in 3rd person
  • hallucinatory voices in running commentary
  • thought broadcasting
  • thought withdrawal , thought insertion
  • influence of others on feelins, drive and volition of common events
  • delusional perception
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17
Q

prevalence of schizophrenia in Uk?

A

1%

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18
Q

name some causes ??? of schizophrenia

A
  • role of family/upbringing
  • obstetrics complications (forcep delivery)
  • winter births
  • illicit drugs (amphetamines, cannabis)
  • genetics (higher incidence in genetic twins)
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19
Q

how to know whether to treat a pt with schizophrenia informally or section them ?

A
  • dependds on risk and insight

low or high risk
if they understand they have schizophrenia then more likely to take drugs

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20
Q

how to do a biopsychosocial assessment of schizophrenia??

A

bio: blood tests, drug tests, CT - rule out organic problem, check compliance
psycho: MSE, collateral Hx
social: carers and housing

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21
Q

biopsychosocial Tx of schizophrenia?

A

bio: antipsychotics
psycho: supportive counselling, family therapy
social: debts, benefits, housing, CPN, social worker

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22
Q

name the types of mood disorders

A
  • depressive disorder
  • bipoalr disorder
  • persistant mood disorder
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23
Q

what are the core symptoms of depression?

A
  • continuous low mood for at least 2 wks
  • lack of energy
  • lack of enjoyment/interest (anhedonia)
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24
Q

what are the somatic/biological symptoms of depression?

A
  • sleep changes
  • appetite and weight changes
  • diurnal variation of mood (mornings are worst)
  • psychomotor retardation/agitation (dont bother getting up)
  • loss of libido
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25
what are the cognititve symptoms of depression>
- low sefl esteem - guilst/self blame - hopelessness - hypochondrical thoughts - poor concentration/attention - suicidal thoughts
26
diagnosis of depression (mild, moderate, severe, severe with psychotic symptoms)
mild - 2 core + 2 others (abel to function) moderate - 2 core + 3/4 others severe - 3 core + at least 4 others severe with psychotic symptoms (auditory hallucinations, delusions)
27
what is the incidnece of PND?
10-15% within 1-2 months post partum
28
symptoms of hypomania?
- mildly elevated, expansive or irritable mood - increased energy/activity - increased self esteeem - sociability, talkativeness over familiarity - increased sex drive - reduced need for sleep - difficulty in focussing on one task alone
29
what is hypomania?
periods of over-active and excited behaviour that can have a significant impact on your day-to-day life. Hypomania is a milder version of mania that lasts for a short period
30
symptoms of mania?
- elevated/expansive/irritable mood (1 week) - icnreased energy/activity - gradiosity//increased self-esteem - pressure of speech - flights of ideas/racing thoughts - distractibility - reduced need to sleep - increased libido - psychotic symptoms (extreme)
31
what are teh two types of persistant mood disorder?
cyclothymia: mild periods of elation/depression, early onset, chronic cause (less severe bipolar disease) dysthymia: chronic low mood not fulfilling the criteria of depression (less severe depression) ** both must be present for 2 yrs to make a diagnosis
32
what is mixed affective state?
characterised by either mixture or a rapid alternation of hypomanic, manic and depressive symptoms
33
what is the definition of bipolar I and bipolar II?
bipolar I: 1 or moe manic episodes or mixed episodes, +- 1 or more depressive episodes bipolar II: 1 or more depressive episodes with at least 1 hypomanic episode
34
causes of mood disroders? (biopsychosocial)
bio: genetic, brain illnesses, physical illnesses, psycho: childhood experiences, view of yourself and the world, personality traits social: work, housing, finances, relationships, support etc
35
Tx of mood disorders?
bio: pharm , ECT (electroconvulsive tx) , rTMS (Repetitive transcranial magnetic stimulation), tDCS (Transcranial direct current stimulation) psycho: psychoeducation, CBT, IPT, psychodynamic, mindfulness social: family, housing, finance, employment, general coping strategies
36
what pharm tx is used in psychiatry
- antidepressants (e.g. SSRIs) - mood stabilisers (lithium, valproate, carbamazepine, lamotrigine) - antipsychotics - anxiolytics
37
what are teh indications for ECT?
- severe depressive illness - life threatening illness - prolonged and severe manic episode - catatonia - high suicide risk - stupor - severe psychomotor retardation
38
what is ECT?
treatment that involves sending an electric current through the brain to trigger an epileptic seizure occurs twice a week, max of 12 treatments
39
what are personality disorders?
conditions in which a idnividual differs significantly from an average person in terms of how they think, percieve, feel or relate to others
40
how many types of personality disorders are they?
10
41
what are the cluster A group of personality disorders?
paranoid: suspicious and mistrustful, misintepreting events as persecutory, bearing grudges, strong sense of personal rights schizoid: detached, solitary, little interest in ppl or sex schizotypal: eccentric, odd behaviour and thinking, unconventional beliefs
42
what are the cluster B group of personality disorder?
borderline: emotional instability, impulsivity, chronic feelings of emptiness, parasuicidal acts, intense and unstable relationships , fear of abandonment narcissistic: present as grandiose, self-important, degrading others antisocial: present wiht unconcern for the feelings of others, disregard rules, impulsivity, low tolerance to fustration, failure to take responsibility historionic: present as theatrical, dramatic, exhibit superficial emotionality, seductiveness, suggestibility
43
what is in cluster C group of personality disorders?
obsessive compulsive: present as rigid, perfectionistic, preoccupied with rules, order and routine, higher snese of morality dependent: present as needing others to make decisions for them, fear abandonment, unable to cope alone, need for resassurance anxious-avoidant: present with persistent anxiety, sensitive to rejection, tend to avoid relationships unless acceptance is guarenteed
44
what is attachment theory?
the emotional bond between parent + child is crucial for childs survival experience of consistent + responsive caregiver gives sense that world is safe and they are loved helps brain develop and enables necessary wiring and chemical connection to allow regulation of feelings
45
Mx for personality disorders?
- harm minimisation (elastic bands or ice cubes on wrists) - emotional management - boundaries (explain expectations of the service user + be consistent and reliable)
46
Tx for personality disorders?
- psychotropic medication only to treat comorbidities - group Tx/therapeutic community - DBT (dialectical behaviourhal therapy) - mentalisation base therapy - transferance focused therapy
47
are children allowed to refuse life saving treatment?
No, they cannot
48
are children allowed to consent to procedures
yes they are - if they have capacity
49
what is the mental capacity act 2005
single test of capacity
50
principles of MCA 2005?
presumption of capacity at all times a new legal right to support individuals in making their own decisions pts have the right to make unwise decisions
51
if a pt is unconcsious and need an op, can you operate?
yes - if its in their best interest - try and consult with next of kin - try to regain pt consciousness beofre op
52
what is the two stage capacity test?
1. is there an impairment of or disturbance in the functioning of a persons mind 2. has it made the person unable to make a particular decision
53
what are the parts of capacity test to understand if a pt has capacity
- understand the information - retain the information - use or weigh up info - communicate decision
54
what are advance decisions?
they are anticipatory refusals only relate to medical tx person must be >18 and have capacity when making AD
55
what are lasting power of attorney?
enables a mentally capable person to plan to incapacity can extend to property, welfare, healthcare matters still have to make decisions in pts best interest
56
what is deprivation of liberty safeguards (DOLS)?
for patients in hospital or care homes who lack capacity - allows pts who are not allowed to leave wards have some freedom e.g. supervised walks MDT assessment
57
what is section 5(4) of the mental health act?
power granted to RMNs to detain an inpatient fro up to 6 hours for medical assessment where mental illness in suspected (cannot be used in ED, need to be admitted to hosp)
58
what is section 5(2) of mental health act?
the consultant or nominated deputy can detain an inpatient for up to 72 hrs under MHA -> to allow fuller assessment and MHA to be completed (cannot be used in ED, need to be admitted to hosp)
59
what is section 2 of the MHA?
2 doctors (1 of whom shld be section 12(2) approved) & 1 AMHP in community or inpatient (not prison) section for max 28 days for assessment + treatment of mental disorder (pt can appeal within first 14 days)
60
what is section 3 of the MHA?
2 doctors (1 of whom shld be section 12(2) approved) & 1 AMHP in community or inpatient (not prison) section for max 6 months for treatment of mental disorder (pt can have 1 appeal)
61
what is section 136 of the MHA?
police power to remove to a place of safety from a public place for an assessment by an AMHP and 1 Dr help up to 72 hrs to allow assessment police to stay with person
62
what is section 17/117 of MHA?
section 17 - whilst detained in hopsital under S2 or S3 a pt may leave under S17 (go on walks, go home) section 117 - anyone whos been under S3 is entitled to S117 aftercare from local authority
63
what is a community treatment order?
patient on S3 can be considered for a CTO pt is well enough to leave hsopital but MUST take tx under supervision of nurses otherwise can be recalled to hospital
64
definiton of suicide
a fatal act of self-injury, udnertaken with more or less conscious self-destructive intent, however vague and ambiguous
65
definition of para-suicide?
similar to suicide - but for whatever reason the victim survived the attempt
66
defintion of deliberate self-harm?
an act of self-harm where the action was not the intention of death, but to cause harm
67
why are men more successful to die from suicide than women?
the way they choose to commit suicide is mroe aggressive therefore higher chance to be successful
68
why are people most likely to commit suicide in the 14 days post discharge from psychiatric hsopital?
- unplanned idscharge - lack on continuity of care - unemployment - suicidal behaviour prior to admission
69
risk factors for suicide
- living alone - Hx of mental illness/suicidal behaviour - unemployment - chronic physical illness - alcohol abuse - drug abuse - FHx - hopelessness - certain professions e.g. vets, soldiers, farmers, doctors
70
what do you ask in a Hx of someone you as attempted suicide
- triggers - preparation e.g. planning in advance, final acts - circumstances e.g alone , precautions against discovery, alcohol, the acts itself, what did they think/want to happen? - after the act e.g. didnt seek help, regret failure, intent - psychiatric Hx + collateral Hx - what do they think now? guilt? ongoing thoughts? - MSE
71
which mental health illnesses have a higher associaition with homicide?
- DSPD - alchohol drug/alcohol misuse - schizophrenia (specific persecutory delusions or hallucinations, command auditory hallucinations)
72
what is anxiety?
feeling on unease, worrying, fear with physiological arousal becomes a problem when someones brain is not able to dsitinuish between physical and psychological threat e.g. false alarm
73
what effect does anxiety have?
physiological arousal racing thoughts inability concentrate cognitive bias - attentional focus
74
what are teh anxiety disorders?
- panic disorder - social anxiety disorder - specific phobias - health anxiety - OCD/BDD - PTSD - GAD
75
definition of specific phobias?
marked fear of specific object or situation e.g. spiders marked avoidance of such object or situations
76
what is panic disorder?
a fear of you own physiological and psychological reactions impending collapse, insanity or death
77
symptoms of panic disorder?
- sense of dread - shaky - feel faint - choking - rapid heart beat - wobbly legs
78
what is GAD?
specific content of (type 1) worries varies included "worries about worries" (type 2 worries) usually accompanied with low level physical symptoms ( insomnia, msucel tension, GI problems, headahce) often maintained by the belief that worry is useful (e.g. motivation, prepares for problems)
79
definition of social anxiety disorder (social phobia)?
fear of negative evaluation by others can lead to avoidance of feared situations, use of safety behaviours, with unhelpful 'port mortems' following social encounters
80
definition of OCD?
unwanted recurring distressing intrusive thoughts or images (=obsessions) e.g. being contaminated, causing harm, aggression impulses, sexual imagery to manage the stress cuased by intrusiosn the pt conducts neutralising behaviours (= compulsions) e.g. washing, checking, praying, counting, repeating words
81
definition of BDD?
characterised by preoccupation with an imagined defect in apperance -> conusuming behviours e.g. mirror gazing, comparing to others
82
definition of PTSD
caused by exposure to event of situation of exceptionally threatening or catastrophic nature which would be likely to cause pervasive distress in almost anyone e.g. warfare, car crash, terrorism
83
3 mian features of PTSD?
- re-experiencing - avoidance - hyperarousal - scan for threats, jumpy
84
common PTSD cormorbities?
substance misuse depression other anxiety disorder
85
problems associated with anxiety disorders?
- icnreased autonomic arousal - alcohol and drug dependence - impaired sleep pattern - avoidance - worry - time consuming anxiety reducing behaviours - procrastination - reduced concentration - impact on functioning - work, social, health
86
differentional diagnsis ofr anxiety
- adjustment disorders or bereavement - other functional psychiatric illnesses - organic cuases: endocrine (thyroid), drug induced (steroids, antihypertensiveS) , neurological (MS, dementia, lupus), alcohol and illicit drug misuse, infection, anaemia,
87
first line Tx of anxiety
CBT - graded expsoure/systematic desensitisation (SSRIs cna be given first line if the pt wants it)
88
side effects of adrenergics (adrenaline e.g.)
- sweating - tremor - headaches - nausea - dizziness
89
commone side effects of muscarinics (acetycholine e.g.)
- dry mouth - difficulty urinatin, urinary retention - difficulty swallowing - thirst - hot and flushed skin - dry skin
90
common side effects of histamine?
- dry mouth - drowsiness - dizziness - N+V
91
name the types of anti-depressants?
- SSRIs (most common as fewer SE) - NSRIs - mirtazapine - tricyclics - MAOIs
92
name some SSRIs
sertraline (first line) citalopram fluoxetine paroxetine vortioxetine
93
commen SE of SSRIs
- restlessness, agitation on initiation - nausea, GI disturbance - headache - weights changes - sexual dysfunction (- bleeding, suicidal ideation)
94
what is the main SE of citalopram?
QTc prolongation
95
what is serotonin syndrom ?
when switching from fluoxetine to another SSRI can get serotonin syndrome (increased serotonin) as fluoxetine has a very long half life headaches agitation hypomania confusions coma shiverin g sweating hyperthermia tachycardia hyperreflexia tremor
96
what is discontinuation syndrome?
caused when antidepressants are stopped too quickly (go slow!) - sweating - shakes - agitation - insomnia - headaches - irritability - n + v - paraesthesia - clonus most commonly in paroxetine and venlafaxine
97
name some NSRIs
- duloxetine - venlafaxine
98
SE of NSRIs?
similar to SSRIs, but greater potential for sedation, nausea and sexual dysfunction
99
SE of mirtazapine?
major SE are sedation and weight gain
100
name some tricyclics?
lofepramine nortriptyline amitriptyline
101
SE of tricyclics?
muscurinic and histamine SE + can cuase QTc prolongatio n and arrythmias
102
name the mian interaction of MAOIs
tyramine reaction = hypertensive crisis therefore avoid foods like cheese, pickled meats, wine
103
SE of antipsychotics?
- sedation - extrapyramidal side effects - weight gain - acute dystonia - oculogyric crisis
104
atypical antipsychotic SE?
weight gain dyslipidaemia and diabetes
105
typical antipsychotics SE?
extra-pyramidal SE dizziness sexual dysfunction
106
name some typical antipsychotics
haloperidol flupenthixol zuclopenthixol chlorpromazine
107
name some atypical antipsychotics?
clozapine (common!) olanzapine risperidone quetiapine
108
name the extrapyramidal SE
bradykinesia muscle stiffness tremor tardive dyskinesia akathisia (parkinsons symptoms basically)
109
what monitoring is needed for antipsychotics?
at beginning: FBC, lipids, LFT, HbA1C, weight, ECG, BP, pulse weekly: weight (they cuase weight gain and diabetes!) three months; FBC, LFT, HbA1C, weight, ECG, BP, pulse yearly:FBC, lipids, HbA1C, weight, ECG, BP, pulse
110
what is the monitoring for ppl on clozapine due to the major SE?
significant potential for agranulocytosis (severe leukopenia) therefore need monitoring of FBC weekly for first 18 weeks
111
major clozapine SEs?
agranulocytosis GI hypomobility = constipation = potentially fatal bowel obstruction hypersalivation urinary incontinence
112
indication fro clozapine
used in schizophrenia after two antipsychotics have been prescribed (because of major SEs)
113
what is neuroleptic malignant syndrome?
rare life threatening reaction to antipsychotics characterised by fever, confusion, muscle rigidity, sweating, autonomic instability death occurs by rhabdomyolysis, renal failure, seizures
114
risk factors for neuroleptic malignant syndrome?
high potency typical antipsychotics in ppl who have never taken antipsychotics high doses young men
115
what is the tx for neuroleptic malignant syndrome?
- emergency referral to A+E, - stop antipsychotics - fluid resus - reduce temp
116
what can be used to treat extra pyramidal side effects in use of antipsychotics?
anticholinergics e.g. - procyclidine (most commonly useD) - benzatropine - trihexphenidyl
117
name the anxiolytic drugs.
beta blockers benzodiazepines pregabalin antidepressants
118
most commonly used beta blocker in anxiety ?
propanolol (contraindicated in asthma !!) not very effective in long term anxiety disorder (not used v often in secondary care, more often in priamry care)
119
why do benzodiazepines have to be used cautiously?
significant potential for misuse, tolerance and dependence use for no more than six wks at once occasionally cause paradoxical disinhibition
120
why is pregabalin being used more in anxiety?
as less potential for misuse and dependence than benzodiazepines (still can be misused - should only be used fro max 6 wks)
121
first line meds for OCD?
high dose antidepressants
122
what drugs are hypnotics (used as sleeping tablets)?
- benzodiazepines (temazepam, lormatazepam nitrazepam) - non benzodiazepines (zopiclone, zolpidem)
123
how are hypnotics given to reduce misuse?
signigficant potential for misuse, dependence, rebound insomnia threefore use for only 2 weeks, take for 5/7 days each week to reduce potential for tolerance
124
what are mood stabiliser drugs?
- lithium - anticonvulsants - second generation (atypical) antipsychotics
125
what is common mental illness that mood stabilisers treat?
bipolar mood disorder
126
SE of lithium?
- GI disurbance - metallic taste and /or dry mouth - fine tremor - polydipsia - polyuria - weight gain - hypothyroidism - renal impairment
127
monitoring on lithium?
U+Es and TFTs because of renal impairments and hypothyroidism
128
symptoms of lithium toxicity?
confusion coarse tremor n+v ataxia seizures **ensure pts are well hydrated to reduce lithium toxicity
129
what is the first line tx for bipolar mood disorder?
quetiapine (a second generation antipsychotic)
130
name some anticonvulsants that can be used as mood stabilisers?
1. sodium valproate (becareful in child bearing age females) 2. carbamazepine 3. lamotrigine 4. pregabalin
131
what drugs are used for cognitive symptoms of dementia?
- acetylcholinesterase inhibitors (donepezil, rivastigmine) - memantine (NMDA receptor antagonist)
132
what drugs are used to treat ADD and ADHD ?
- methylphenidate (aka ritalin) - dextroamphetamine - atomexetine
133
what are personality disorders?
A personality disorder is a condition that affects how you think, feel, behave or relate to other people
134
what is dissocial personality disorder?
characterized by disregard for social obligations, and callous unconcern for the feelings of others, can become violent + tendancy to blame others amoral antisocial asocial psychopathic sociopathic
135
what is emotionally unstable personality disorder? (also known as borderline personality disorder)
tendency to act impulsively and without consideration of the consequences aggressive borderline explosive
136
Tx for personality disorders?
CPA (care programme approach) psychotherapy dialectal behaviour therapy only treat iwrth drugs ifthere are co-morbidities (e.g. anxiety, depression)
137
what is autism spectrum disorder?
- persistent deficits to initiate and sustain social interaction and communication - restricted, repetitive and inflexible patterns of behaviour +/- interests that are atypical or excessive for the individual's age and sociocultural context +/- Sensory differences
138
name some comorbidities with ASD?
- epilepsy - visual or hearign impairment - mental health (depression, anxiety, OCD) - learnign disability - sleep disorders
139
Mx of autism?
bio: meds for comorbidities psycho: early intensive behavioural intervention (EIBI) - interventions for behaviour that challenges - positive behavioural support (PBS) - family therapy - communications interventions (SALT) - OT (sensory integration therapy) (- music therapy) (- advise from dietician) social: social worker to work w family, school challenges, do they need to go to placements?
140
name some important variables when assessing a patients risk (dynamic and static)
static: gender, personality disorders, genetics, previous history of self harm, adverse childhood event dynamic risk factor - mental disorder, substance misuse, bereavement, unemployment, no social contact, comorbid physical conditions, age, marital status
141
what sedative would you give to a patient who has delirium and de escalation methods havent worked
IM haloperidol
142
what sedative would you give to a patient (with parkinsons or lewy body dementia) who has delirium and de escalation methods havent worked
IM lorazepam as IM haloperidol can cause extrapyramidal SE
143
what are teh highest causes of mortality due to alcohol?
- fights and falls - lvier failure - pancreatitis - overdose - withdrawal - wernikes encephalopathy
144
symptoms of alcohol toxicity?
head injury confusion shaking/seizures hallucinations vomit blood or coffee grounds severe abdo pain sudden yellow
145
signs of early alcohol withdrawal?
- tremor - sweating - nausea - anxiety - tachycardia
146
signs of late alcohol withdrawal
- delirium tremens - disorientation - hallucination -tremor - BP, pulse, fever, motor incoordination
147
signs nd symptoms of wernickes encephalopathy?
- ataxia - nystagmus - opthalmoplegia - altered consiousness - fever - hypothermia - ptosis - abnormal pupillary reflexes
148
cause fo wernickes encephalopathy?
deficiecny of vitamin B1
149
treatment of wernickes encephalopathy?
parenteral thiamine
150
what is korasakoffs syndrome?
caused from long term thiamine deficiency (long term wernickes encephalopathy) signs are same as wernickes plus short term memory loss - nroamlly need to go into care/need carer
151
sign of opiate overdose?
- pinpoint pupils - decreasing consciousness - slow breathing - death
152
Tx of opiate overdose?
naloxone IM
153
signs of opiate withdrawal?
- sweting - rhinorrhea - tachycardia - restlessness - dilated pupils - lacrimation - goosebumps later: - N+V - diarrhoea - insomnia - abdo cramps - muscle pains
154
tx for opiate withdrawal ?
- methadone
155
what is the tx for benzo withdrawl?
diazepam - as it is long acting
156
which two antidepressants are used preferred for patients who are breastfeeding?
sertraline and paroxetine