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841 LAB FORMULARY > Psychiatric Medication Formulary CYP and SE > Flashcards

Psychiatric Medication Formulary CYP and SE Flashcards

1
Q

Amitriptyline (Elavil)

A

2D6 substrate

Anticholinergic effects, cardiovascular, wt gain

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2
Q

Aripiprazole (Abilify)

A

3A4/2D6 substrate

akathisia/anxiety

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3
Q

Asenapine (Saphris)

A

1A2 substrate

wt gain, QTc prolongation

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4
Q

Bupropion (Wellbutrrin/Zyban)

A

2B6 substrate

insomnia/appetite suppression

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5
Q

Chlorpromazine (Thorazine)

A

2D6 substrate/inhibitor

EPS, drowsiness, or rash

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6
Q

Citalopram (Celexa)

A

2C19 substrate

akathisia, sedation, sexual dysfunction

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7
Q

Clozapine (Clozaril)

A

1A2 substrate

Agranulocytosis, cardiomyopathy

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8
Q

Desvenlafaxine (Pristiq)

A

renal excretion

sedation, nausea, increased bp, GI upset

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9
Q

Fluvoxamine (Luvox)

A

1A2 inhibitor

indicated for OCD, sedation, sexual dysfunction

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10
Q

Levomilnacipran (Fetzima)

A

3A4 substrate

sedation, nausea, increased bp, GI upset

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11
Q

Lurasidone (Latuda)

A

3A4 substrate

take with food, prominent akathisia

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12
Q

Milnacipran (Savella)

A

renal excretion

not indicated for depression, sedation, nausea, increased BP

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13
Q

Olanzapine (Zyprex)

A

1A2 substrate

significant wt gain, metabolic syndrome risk

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14
Q

Quetiapine (Seroquel)

A

3A4 substrate

QTc prolongation, abuse potential

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15
Q

Risperidone (Risperdal)

A

2D6 substrate

EPS, hyperprolactinemia

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16
Q

Sertraline (Zoloft)

A

2C19/2D6 substrate

GI at higher doses, sexual dysfunction, sedation

17
Q

Trazodone (Desyrel)

A

3A4 substrate

priapism, clinically more useful for insomnia

18
Q

Venlafaxine (Effexor)

A

3A4/2D6 substrate

dose must be > 150mg for NE effects, elevated BP, sexual dysfunction

19
Q

Vilazodone (Viibryd)

A

3A4 substrate

insomenia, nausea, diarrhea

20
Q

Vortioxetine (Brintellix)

A

2D6 substrate

N/V, constipation

21
Q

Ziprasidone (Geodon)

A

aldehyde oxidase

must take with food, QTc prolongation

841 LAB FORMULARY (5 decks)

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