Psych Flashcards
Most common cause on intellectual disability
Fetal alcohol syndrome
Most common genetic causes of intellectual disability
Down and Fragile X
Deficits in Autism spectrum disorders
Social interactions, behavior, and language
ASD is also with which perinatal infections?
Rubella and CMV
ASD patients have a higher incidence of …
abnormal ECG, seizures, and abnormal brain morphology
Which drugs are approved for tx of irritability in ASD?
Risperidone and aripiprazole
ADHD is asso w lower levels of …
dopamine
Disruptive mood dysregulation disorder (DMDD) features
Chronic, severe, persistent irritability with temper outbursts and angry, irritable, or sad mood between outbursts. Should not be dx’ed before age 6 or after 18.\
Intermitten explosive disorder features
not aggressive on a continuous basis; periods of good behavior
Tourette disorder is asso w what other psych disorders?
ADHD and OCD
MDD is asso w decreased levels of …
NE, 5HT, and DA
How is sleep affected in MDD?
Decreased REM latency, increased REM
Tx of depression + neuropathy
Duloxetine (an SNRI)
Tx of depression +/- fear of gaining weight / sexual s/e’s +/- desire to quit smoking
Bupropion
Tx of depression + insomnia + decreased appetite
Mirtazapine
Bipolar disorder is asso with increased levels of…
NE and 5HT
Bipolar disorder type I features
Mania (>1 week, affects function, warrants hospitalization) + depression
Bipolar disorder type II features
Hypomania (<1 week, does not severely affect function) + depression
Tx of acute mania
Lithium and valproate, may use atypical antipsychotics (e.g. quetiapine) and anticonvulsant lamotrigine
Tx if acute mania + severe sxs
Use atypical antipsychotics (quetiapine) d/t shorter onset of action
Tx of mania in pregnancy
Lurasidone, risk of fetal EPS in third trimester
This is never a correct answer on STEP 2
refer to psych
Persistent depressive disorder timing
> 2 years
Cyclothymic disorder features and tx
Hypomanic episodes + mild depression, >2 years, tx w lithium, valproate, antipsychotics, or psychotherapy
Tx of major depressive disorder with seasonal pattern
phototherapy and bupropion or SSRI
Seasonal affect disorders so with abnormal…
melatonin metabolism
Duration of postpartum blues or “baby blues”
birth to 2 weeks
Duration of depressive disorder with peripartum onset
within 1-3 weeks after birth
Duration of bipolar disorder with peripartum onset and brief psychotic disorder with peripartum onset
during pregnancy up to 4 weeks after birth
Bereavement duration
typically lasts less than 6 mo to 1 yr
Litium s/e’s
tremors, weight gain, GI disturbance, nephrotox, diabetes insidious, leukocytosis, teratogenic
severe tox: confusion, ataxia, lethargy, abnormal reflexes
Valproate s/e’s
Tremors, weight gain, GI disturbance, alopecia, teratogenic, hepatoxicity (elevated LFTs). Must monitor levels of the drug. Tox: hyponatremia, coma, death.
Serotonin syndrome unique feature and tx
Neuromuscular irritability (hyperreflexia and myoclonus); strop the medication and give cyproheptadine (serotonin antagonist)
Neuroleptic malignant syndrome unique feature and tx
Rigidity; most important intervention is d/c’ing the offending drug and if refractory use dantrolene or bromocriptine
Brieft psychotic disorder duration
> 1 day, <1 mo
Schizophreniform duration
> 1 mo, <6 mo
Schizophrenia duration
> 6 mo