Psych Flashcards

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1
Q

What drugs cause weight gain?

A

Mirtazapine, Olanzapine, Clozapine

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2
Q

What drug for depression in pregnancy?

A

Sertraline

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3
Q

What mood stabiliser in breast feeding?

A

Lamotrigine

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4
Q

Old lady who has insomnia?

A

Give her mirtazapine

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5
Q

What is the least sedating antipsychotic?

A

Aripirazole (atypical)

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6
Q

What antidepressants are not sedating?

A

Most SSRIs are not sedating and duloxetine is not sedating.

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7
Q

What antidepressant in children

A

Fluoxetine

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8
Q

What is the only antipsychotic that does not cause weight gain?

A

aripiprazole

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9
Q

What antidepressants do not cause you to gain weight?

A

Fluoxetine and duloxetine.

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10
Q

What class of antidepressants should you avoid in the elderly?

A

SSRIs

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11
Q

MAOI + SSRI can cause what

A

Serotonin Syndrome

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12
Q

What treatment for delirium? What if they have Parkinson’s /Lewy body dementia?

A

haloperidol, quetiapine

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13
Q

3 side effects of SNRIs?

A

venlafaxine and duloxetine,

hypertension
insomnia
cardiac arrhythmias.

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14
Q

TCAs

A

Amitriptyline, imipramine, dosulepin, clomipramine, nortriptyline, trazodone

contraindicated in post MI patients

Anti cholinergic side effects.

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15
Q

HPT axis in depression

A

TSH to TRH response blunted in 20 - 25% despite normal TSH, T3 and T4

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16
Q

HPA axis in major depression

A

50-70% fail to suppress cortisol production following administration of dexamethasone.

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17
Q

Brain imaging in OCD?

A

Increased metabolism and blood flow in orbitofrontal cortex, caudate nucleus and cingulate cortex.

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18
Q

Memory encoding location?

A

Ventrolateral pre frontal cortex and medial temporal cortex.

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19
Q

How do we measure white matter tracks in schizophrenia?

A

Diffusion tension imagine (DTI)

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20
Q

Mesolimbic / cortical pathway

A

Motivation and reward.

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21
Q

D1 and D5

A

Stimulate cAMP

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22
Q

D2, D3, D4

A

inhibit Ca2+, open K+ channels

23
Q

Borderline learning difficulty

A

70-80

24
Q

Mild LD

A

50-69

25
Q

Moderate LD

A

35-49

26
Q

Severe LD

A
27
Q

Profound

A
28
Q

How do we calculate IQ?

A

mental age/chronological age x 100

29
Q

Schizophrenia is 3x more common in people who have learning difficulties

A

Depression is 3x more common in people who have learning difficulties.

30
Q

Functional hemiparesis brain imaging

A

Increased rCBF bilaterally in frontal and parietal cortex in resting states.

31
Q

First rank symptoms

A

Delusional perception

Passivity (Delusions of control)

Auditory Hallucination

Delusions of though interference

32
Q

Social anxiety treatment

A

Moclobemide

33
Q

Social phobia imaging

A

increased bilateral activation of amygdala that normalises after treatment

34
Q

Treatment of neuroleptic malignant syndrome?

A

Dantrolene and bromocriptine (dopamine agonist)

35
Q

Selective abstraction

A

Focus on one -ve detail, colours entire experience.

36
Q

Schizophrenia Dx?

A

Diagnosed after 6 months of symptoms:

1 first rank
OR
2 negative symptoms

37
Q

CAGE

A

C ut down
A angry when people talk about your drinking
G uilty
E ye opener, drink in morning

38
Q

Orbitofrontal cortex

A

Key creator of motivation to act

Addicts show increased activation of OFC when presented with drug cues.

The changes persist into abstinence.

39
Q

End of life medication

A

Resp secretions = buscopan

Nausea = Levopromazine

Distress = midazolam

Pain / SOB = Morphine

40
Q

Increase of what in alcohol dependence?

A

Increased levels of GABA.

41
Q

Withdrawal alcohol seizures?

A

0 - 48 hours

42
Q

Delirium Tremens

A

48 - 72 hours.

43
Q

What is the only atypical antipsychotic not to cause EPSE?

A

Clozapine (only antipsychotic to act on D4)

44
Q

What atypical is more likely to cause hyperprolactinaemia?

A

Risperidone

45
Q

Treatment of Borderline PD

A

DBT

46
Q

Treatment of Avoidant PD

A

Social Skills training

47
Q

Cluster A personality Disorder

A

Schizoid
Paranoid
Schizotypal

48
Q

Cluster B Personality Disorder

A

Borderline
Histrionic
Antisocial

49
Q

Cluster C

A

Obsessive compulsive
Avoidant
Dependent

50
Q

Carbamazepine side effects?

A
Dizzy and drowsy
N & V
Dry mouth and swollen tongue
Hypothyroid
Aplastic anaemia
51
Q

Lamotrigdine side effects

A

SJS
Sedation
Ataxia
Insomnia

52
Q

B Blockers side effects

A

Fatigue, cold peripheries, erectile dysfunction

53
Q

Statins side effects

A

Myalgia

54
Q

Autism Treatment

A

Risperidone for short term aggression
Ritalin for ADHD symptoms
Melatonin = difficulty sleeping.