Psych Flashcards
What drugs cause weight gain?
Mirtazapine, Olanzapine, Clozapine
What drug for depression in pregnancy?
Sertraline
What mood stabiliser in breast feeding?
Lamotrigine
Old lady who has insomnia?
Give her mirtazapine
What is the least sedating antipsychotic?
Aripirazole (atypical)
What antidepressants are not sedating?
Most SSRIs are not sedating and duloxetine is not sedating.
What antidepressant in children
Fluoxetine
What is the only antipsychotic that does not cause weight gain?
aripiprazole
What antidepressants do not cause you to gain weight?
Fluoxetine and duloxetine.
What class of antidepressants should you avoid in the elderly?
SSRIs
MAOI + SSRI can cause what
Serotonin Syndrome
What treatment for delirium? What if they have Parkinson’s /Lewy body dementia?
haloperidol, quetiapine
3 side effects of SNRIs?
venlafaxine and duloxetine,
hypertension
insomnia
cardiac arrhythmias.
TCAs
Amitriptyline, imipramine, dosulepin, clomipramine, nortriptyline, trazodone
contraindicated in post MI patients
Anti cholinergic side effects.
HPT axis in depression
TSH to TRH response blunted in 20 - 25% despite normal TSH, T3 and T4
HPA axis in major depression
50-70% fail to suppress cortisol production following administration of dexamethasone.
Brain imaging in OCD?
Increased metabolism and blood flow in orbitofrontal cortex, caudate nucleus and cingulate cortex.
Memory encoding location?
Ventrolateral pre frontal cortex and medial temporal cortex.
How do we measure white matter tracks in schizophrenia?
Diffusion tension imagine (DTI)
Mesolimbic / cortical pathway
Motivation and reward.
D1 and D5
Stimulate cAMP