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Therapeutics > Psych > Flashcards

Psych Flashcards

1
Q

Anorexia approved drug

A

NONE

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2
Q

Binge eating approved drug

A

Lisdexamphetamine (Vyvanse)

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3
Q

Bulimia approved drug

A

Fluoxetine (Prozac)

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4
Q

Tic disorder 1st line

A

alpha 2 agonists (guanfacine/clonidine)

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5
Q

Tic disorder 2nd line

A

atypical antipsychotics (aripiprazole and risperidone)

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6
Q

Tic disorder 3rd line

A

typical antipsychotic (haloperidol and pimozide)

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7
Q

ODD and Conduct disorder 1st line

A

stimulants

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8
Q

Pediatric age approved for ARIPIPRAZOLE

A

6-17 yo

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9
Q

Pediatric age approved for RISPERIDONE

A

5-16 yo

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10
Q

Pediatric age approved for FLUOXETINE

A

8 yo

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11
Q

Pediatric age approved for escitalopram

A

12 yo

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12
Q

Clozapine

A

1A2 substrate, QTc prolongation

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13
Q

Olanzapine

A

1A2 substrate, high risk of metabolic syndrome

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14
Q

Zyprexa Reprevv

A

post dose delirium syndrome can happen up to 24 hours after

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15
Q

Quetiapine

A

3A4 substrate. boxed warning for suicidal ideation

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16
Q

Risperidone

A

2D6 substrate

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17
Q

Risperdal Consta

A

weekly inj. 4 week oral supplement

18
Q

Perseris

A

q4w subcutaneous abdominal injection. 3A4 substrate. Risperidone

19
Q

Rykindo

A

q2w. 1 week oral supplement

20
Q

Uzedy

A

abdominal or upper arm subcutaneous injection. Risperidone

21
Q

Paliperidone

A

RENALLY eliminated (monitor CrCl). QTc prolongation

22
Q

Invega Sustenna

A

load- booster-then every 4 weeks. IN DELTOID not gluteal

23
Q

Invega Trinza

A

q3m may be given after 4 months of Sustenna

24
Q

Invega Hafyra

A

q6m may be given after 4 months of Sustenna or after 1 dose of Trinza. GLUTEAL ONLY

25
Q

Iloperidone

A

2D6 substrate. QTc prolongation high risk for syncope

26
Q

Ziprasidone

A

3A4 substrate. QTc prolongation

27
Q

Asenapine sublingual and patch

A

1A2 substrate and QTc prolongation

28
Q

Lurasidone

A

3A4 substrate high risk for akathEsia

29
Q

Pimavanserin

A

Parkinsons + hallucinations. INVERSE agonist. 3A4 substrate

30
Q

Brexpiprazole

A

2D6/3A4 substrate

31
Q

Aripiprazole

A

2D6/3A4 substrate

32
Q

Cariprazine

A

3A4 substrate. high risk of akathesia

33
Q

Lumateperone

A

low risk of side effects. 3A4 substrate

34
Q

VMAT inhibitors

A
  • Benazine treat tardive dyskinesia 2D6 substrate and 3A4 substrate
35
Q

2D6 substrates

A

DECREASE dose with fluoxetine or paroxetine

36
Q

1A2 substrates

A

INCREASE dose with cigarette smoking/ DECREASE dose with fluvoxamine

37
Q

3A4 substrates

A

INCREASE dose with carbamazepine or phenobarbital / decrease dose with conazoles

38
Q

Benzos with PTSD

A

NO

39
Q

BENZO MOA

A

increases frequency of GABA channel opening. hyperpolarizes cell with increased Cl- influx

40
Q

BARBITURATE MOA

A

increases duration of GABA channel opening. dangerous overdose!!!

Therapeutics (8 decks)

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