Psych

Question 1

Anorexia approved drug

Answer 1

NONE

Question 2

Binge eating approved drug

Answer 2

Lisdexamphetamine (Vyvanse)

Question 3

Bulimia approved drug

Answer 3

Fluoxetine (Prozac)

Question 4

Tic disorder 1st line

Answer 4

alpha 2 agonists (guanfacine/clonidine)

Question 5

Tic disorder 2nd line

Answer 5

atypical antipsychotics (aripiprazole and risperidone)

Question 6

Tic disorder 3rd line

Answer 6

typical antipsychotic (haloperidol and pimozide)

Question 7

ODD and Conduct disorder 1st line

Answer 7

stimulants

Question 8

Pediatric age approved for ARIPIPRAZOLE

Answer 8

6-17 yo

Question 9

Pediatric age approved for RISPERIDONE

Answer 9

5-16 yo

Question 10

Pediatric age approved for FLUOXETINE

Answer 10

8 yo

Question 11

Pediatric age approved for escitalopram

Answer 11

12 yo

Question 12

Clozapine

Answer 12

1A2 substrate, QTc prolongation

Question 13

Olanzapine

Answer 13

1A2 substrate, high risk of metabolic syndrome

Question 14

Zyprexa Reprevv

Answer 14

post dose delirium syndrome can happen up to 24 hours after

Question 15

Quetiapine

Answer 15

3A4 substrate. boxed warning for suicidal ideation

Question 16

Risperidone

Answer 16

2D6 substrate

Question 17

Risperdal Consta

Answer 17

weekly inj. 4 week oral supplement

Question 18

Perseris

Answer 18

q4w subcutaneous abdominal injection. 3A4 substrate. Risperidone

Question 19

Rykindo

Answer 19

q2w. 1 week oral supplement

Question 20

Uzedy

Answer 20

abdominal or upper arm subcutaneous injection. Risperidone

Question 21

Paliperidone

Answer 21

RENALLY eliminated (monitor CrCl). QTc prolongation

Question 22

Invega Sustenna

Answer 22

load- booster-then every 4 weeks. IN DELTOID not gluteal

Question 23

Invega Trinza

Answer 23

q3m may be given after 4 months of Sustenna

Question 24

Invega Hafyra

Answer 24

q6m may be given after 4 months of Sustenna or after 1 dose of Trinza. GLUTEAL ONLY

Question 25

Iloperidone

Answer 25

2D6 substrate. QTc prolongation high risk for syncope

Question 26

Ziprasidone

Answer 26

3A4 substrate. QTc prolongation

Question 27

Asenapine sublingual and patch

Answer 27

1A2 substrate and QTc prolongation

Question 28

Lurasidone

Answer 28

3A4 substrate high risk for akathEsia

Question 29

Pimavanserin

Answer 29

Parkinsons + hallucinations. INVERSE agonist. 3A4 substrate

Question 30

Brexpiprazole

Answer 30

2D6/3A4 substrate

Question 31

Aripiprazole

Answer 31

2D6/3A4 substrate

Question 32

Cariprazine

Answer 32

3A4 substrate. high risk of akathesia

Question 33

Lumateperone

Answer 33

low risk of side effects. 3A4 substrate

Question 34

VMAT inhibitors

Answer 34

- Benazine treat tardive dyskinesia 2D6 substrate and 3A4 substrate

Question 35

2D6 substrates

Answer 35

DECREASE dose with fluoxetine or paroxetine

Question 36

1A2 substrates

Answer 36

INCREASE dose with cigarette smoking/ DECREASE dose with fluvoxamine

Question 37

3A4 substrates

Answer 37

INCREASE dose with carbamazepine or phenobarbital / decrease dose with conazoles

Question 38

Benzos with PTSD

Answer 38

NO

Question 39

BENZO MOA

Answer 39

increases frequency of GABA channel opening. hyperpolarizes cell with increased Cl- influx

Question 40

BARBITURATE MOA

Answer 40

increases duration of GABA channel opening. dangerous overdose!!!