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Therapeutics > ANS Overview > Flashcards

ANS Overview Flashcards

1
Q

Sympathetic (ANS)

A

Fight or Flight

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2
Q

Parasympathetic (ANS)

A

Rest and Digest

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3
Q

Preganglionic neuron

A

Located in CNS

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4
Q

Postganglionic neuron

A

Peripheral neuron, and projects to the target organ

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5
Q

Acetylcholine (ACh)

A

A primary transmitter of all preganglionic neurons and also a transmitter in PSNS postganglionic neurons

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6
Q

Norepinephrine (NE)

A

Transmitter in most SNS postganglionic neurons

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7
Q

Neuron length

A

PSNS= long to short. SNS= short to long

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8
Q

Sweat gland neurotransmitter

A

Postganglionic= norepinephrine for stress or acetylcholine for thermoregulation

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9
Q

Receptor agonist

A

Mimic neurotransmitters and activate receptors

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10
Q

Receptor antagonist

A

Block neurotransmitters and block the endogenous neurotransmitters from activating receptors

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11
Q

ParasympathOMIMETIC

A

Mimic ACh (AGONIST)

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12
Q

ParasympathOLYTIC

A

Block ACh (ANTAGONIST)

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13
Q

SympathOMIMETIC

A

Mimic NE (AGONIST)

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14
Q

SympathOLYTIC

A

Block NE (ANTAGONIST)

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15
Q

Muscarinic Cholinergic Receptor (M1,3,5)

A

Signal via Gq with second messengers IP3 and DAG

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16
Q

Muscarinic Cholinergic Receptor (M2,4)

A

Signal via Gi pathway and inhibits second messenger cAMP

17
Q

Nicotinic Cholinergic Receptor

A

Ionotropic which opens ligand-gated Na+ channels

18
Q

Adrenergic Receptor a1

A

Signal via Gq pathway with second messengers IP3 and DAG

19
Q

Adrenergic Receptor a2

A

Signal through Gi which inhibits adenylyl cyclase and reduces cAMP

20
Q

Adrenergic Receptor B1,2,3

A

Signal through Gs which activates adenylyl cyclase and increases cAMP

21
Q

PSNS effect on EYE

A

Contraction of the pupil (miosis) and focusing of the lens

22
Q

PSNS effect on GLANDS

A

Increase secretion

23
Q

PSNS effect on AIRWAY

A

Constrict bronchi and secretion of mucous

24
Q

PSNS effect on HEART

A

Decrease rate (bradycardia) and decreased force

25
Q

PSNS effect on GUT

A

Stimulated

26
Q

PSNS effect on BLADDER

A

Stimulated

27
Q

SNS effect on EYE

A

Dilation of the pupil (mydriasis)

28
Q

SNS effect on AIRWAY

A

Relax bronchi

29
Q

SNS effect on HEART

A

Increase rate (tachycardia), Increased force

30
Q

SNS effect on GUT

A

Inhibition

31
Q

SNS effect on BLADDER

A

Inhibition

32
Q

SNS effect on UTERUS (premature labor)

A

Relaxation

33
Q

SNS effect on GLANDS

A

Increased secretions

Therapeutics (8 decks)

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